Peptide Bond Resonance and Rotations Quiz
18 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which type of amino acid is most likely to disrupt the α-helix structure due to impossible bond rotation?

  • Leucine
  • Alanine
  • Proline (correct)
  • Glycine
  • In an α-helix, which amino acids are considered strong helix formers?

  • Phenylalanine and Tryptophan
  • Proline and Glycine
  • Alanine and Leucine (correct)
  • Lysine and Arginine
  • Which type of amino acid is known to have a positive charge on its side chain?

  • Lysine (correct)
  • Valine
  • Serine
  • Glutamine
  • How does the sequence of amino acids affect the stability of an α-helix?

    <p>It affects the formation of hydrogen bonds within the helix</p> Signup and view all the answers

    Which feature of the peptide bond contributes to the large macroscopic dipole moment of the α-helix?

    <p>The amide group having a negative charge</p> Signup and view all the answers

    Why are peptide bonds aligned roughly parallel with the helical axis in an α-helix?

    <p>To maximize hydrogen bonding potential</p> Signup and view all the answers

    What type of structure is formed by hydrogen bonds between the backbone amides in different strands of a β sheet?

    <p>Sheet</p> Signup and view all the answers

    Which type of β sheet has strands that are oriented in the same direction?

    <p>Parallel sheet</p> Signup and view all the answers

    What creates a pleated sheet-like structure in a β sheet?

    <p>Tetrahedral geometry of the α carbon</p> Signup and view all the answers

    In antiparallel β sheets, how are the H-bonded strands oriented?

    <p>In opposite directions</p> Signup and view all the answers

    What type of interactions are called sheets in β structures?

    <p>Hydrogen bonds</p> Signup and view all the answers

    How do the hydrogen bonds between strands in parallel β sheets differ from antiparallel β sheets?

    <p>They are linear in parallel sheets and bent in antiparallel sheets.</p> Signup and view all the answers

    Which factor contributes to peptide bonds being less reactive compared to esters?

    <p>Rigidity and stability</p> Signup and view all the answers

    Why is rotation around the peptide bond not permitted?

    <p>Resonance structure</p> Signup and view all the answers

    In a fully extended polypeptide, what are the angles for rotation around the α carbon—amide nitrogen bond and the α carbon—carbonyl carbon bond?

    <p>(180°, 180°)</p> Signup and view all the answers

    What determines the secondary structure of a protein?

    <p>Organization around the peptide bond and identity of the R groups</p> Signup and view all the answers

    What is the energy change (ΔGº') for peptide bond hydrolysis?

    <p>-10 kJ/mol</p> Signup and view all the answers

    What defines oligopeptides compared to polypeptides?

    <p>Number of residues</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Browser