Podcast
Questions and Answers
What is the recommended treatment duration for aminoglycoside therapy in penicillin-resistant cases of infective endocarditis?
What is the recommended treatment duration for aminoglycoside therapy in penicillin-resistant cases of infective endocarditis?
- Exactly 2 weeks
- More than 2 weeks (correct)
- Can vary based on patient stability
- Less than a week
What is recommended when a patient with infective endocarditis caused by resistant isolates is clinically stable after 10-14 days of therapy?
What is recommended when a patient with infective endocarditis caused by resistant isolates is clinically stable after 10-14 days of therapy?
- Increase the dosage of antibiotics
- Continue the same treatment indefinitely
- Consider switching to daptomycin therapy
- Consider OPAT or outpatient oral antibiotic therapy (correct)
What percentage of patients in the retrospective series were treated with penicillin or ceftriaxone for infective endocarditis caused by penicillin-resistant streptococci?
What percentage of patients in the retrospective series were treated with penicillin or ceftriaxone for infective endocarditis caused by penicillin-resistant streptococci?
- 78% (correct)
- 10%
- 30%
- 50%
What is indicated if a patient has infective endocarditis caused by resistant isolates and is not clinically stable after 10-14 days of therapy?
What is indicated if a patient has infective endocarditis caused by resistant isolates and is not clinically stable after 10-14 days of therapy?
What is the incidence of resistant S.mitis and Streptococcus oralis reported in large strain collections?
What is the incidence of resistant S.mitis and Streptococcus oralis reported in large strain collections?
Which antibiotic therapy is not recommended for short-term regimens in penicillin-resistant cases?
Which antibiotic therapy is not recommended for short-term regimens in penicillin-resistant cases?
What is the recommended treatment for penicillin-susceptible strains without meningitis?
What is the recommended treatment for penicillin-susceptible strains without meningitis?
In cases of meningitis, why should penicillin be avoided?
In cases of meningitis, why should penicillin be avoided?
For infective endocarditis caused by group A streptococci, what is their susceptibility to beta-lactams?
For infective endocarditis caused by group A streptococci, what is their susceptibility to beta-lactams?
What is recommended when treating infective endocarditis due to the Streptococcus anginosus group?
What is recommended when treating infective endocarditis due to the Streptococcus anginosus group?
After 10-14 days of therapy for meningitis cases, what treatment option should be considered if the patient is clinically stable?
After 10-14 days of therapy for meningitis cases, what treatment option should be considered if the patient is clinically stable?
What is the recommended treatment when encountering penicillin-resistant strains without meningitis?
What is the recommended treatment when encountering penicillin-resistant strains without meningitis?
What is the mortality rate associated with group B infective endocarditis?
What is the mortality rate associated with group B infective endocarditis?
Which streptococci induce infective endocarditis with large vegetations and high rates of complications?
Which streptococci induce infective endocarditis with large vegetations and high rates of complications?
What antibiotic is no longer recommended for staphylococcal native valve endocarditis due to increased renal toxicity?
What antibiotic is no longer recommended for staphylococcal native valve endocarditis due to increased renal toxicity?
In penicillin-allergic patients with MSSA endocarditis, what antibiotic can be used if beta-lactams are contraindicated?
In penicillin-allergic patients with MSSA endocarditis, what antibiotic can be used if beta-lactams are contraindicated?
In infective endocarditis caused by Staphylococcus aureus, what is the preferred treatment if vancomycin is deemed inferior to beta-lactams?
In infective endocarditis caused by Staphylococcus aureus, what is the preferred treatment if vancomycin is deemed inferior to beta-lactams?
What is the rationale behind adding rifampin after 3–5 days of effective antibiotic therapy once the bacteraemia has been cleared in Staphylococcus aureus endocarditis?
What is the rationale behind adding rifampin after 3–5 days of effective antibiotic therapy once the bacteraemia has been cleared in Staphylococcus aureus endocarditis?
