29 Questions
What is the primary benefit of heliox therapy in reducing the work of breathing?
Conversion of turbulent flow to laminar flow
What is a condition that may delay the normal relaxation of the pulmonary bed?
All of the above
What is a key characteristic of helium that makes it safe for use in medical treatments?
It is inert and non-toxic
What is the therapeutic aim of iNO administration to pediatric patients with ARDS?
To reduce PH and intrapulmonary shunting
What is the purpose of combining helium with oxygen in medical treatments?
To make the mixture compatible with life
What percentage of neonates with persistent pulmonary hypertension of the newborn do not respond or sustain a response to iNO?
40%
What is the purpose of the iNOmax DSIR?
To provide a constant dose of iNO to the inspiratory limb of the circuit
What is the consequence of failing to maintain a reliable air or oxygen gas source when using a blending system?
Administration of 100% helium
What is the Reynold's number (Re) that describes turbulent flow through a tube?
Re >4000
What should be considered if oxygenation and hemodynamic parameters do not improve despite interventions?
ECMO
What has been demonstrated by multiple large studies regarding the effect of iNO?
An improvement in oxygenation and a reduction in the need for ECMO
What is the mixture of helium and oxygen often referred to as?
Heliox
What is a condition associated with hypoxic respiratory failure that may be treated with heliox therapy?
Persistent pulmonary hypertension of the newborn
What is the molecular weight of helium?
4 grams
What is the relationship between the density of a gas and its benefit to gas flow during ventilation under turbulent conditions?
The lower the density, the greater the benefit
What is the measure of the magnitude to which a fluid in motion resists flow?
Viscosity
What is the viscosity of heliox 80/20?
203.6 poise (μP)
What are the components that make up the tracheobronchial tree?
Trachea, carina, left and right mainstem bronchi, lobar bronchus, segmental bronchus, bronchi, and the alveolar ducts and sacs
What is the typical weaning process for iNO?
Stepwise dose reductions
What is the recommended time period between iNO dose changes during weaning?
4 hours
Why is it important to optimize alveolar recruitment during iNO administration?
To increase the dilation effect on the pulmonary vasculature
What is a common limitation of iNO therapy?
It has a high cost and requires a complex delivery system
What medication has been shown to ameliorate rebound PH during weaning and discontinuation of iNO therapy?
Sildenafil
What may be necessary when iNO reaches 1 ppm or is discontinued?
Increasing the FiO2
What is a potential complication of discontinuing iNO therapy?
Rebound PH
What happens to endogenous NO production during iNO therapy?
It decreases
What can occur shortly following discontinuation of iNO therapy?
Increase in pulmonary artery pressure and decrease in PaO2
What is the duration of the transitional period after discontinuation of iNO therapy?
30 minutes
What can be used to prevent rebound PH during the transitional period?
Sildenafil administration and increased FiO2
This quiz covers the topic of helium-oxygen mixtures, also known as heliox, in pediatric respiratory care. It explores the properties of helium and its use in medical therapy.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
