Podcast
Questions and Answers
What is the treatment of choice for PBC patients with end-stage liver disease?
What is the treatment of choice for PBC patients with end-stage liver disease?
- Kidney dialysis
- Lung transplant
- Liver transplantation (correct)
- Heart bypass surgery
Which autoimmune disease is a well-known cause of chronic liver disease in childhood?
Which autoimmune disease is a well-known cause of chronic liver disease in childhood?
- Rheumatoid arthritis
- Autoimmune hepatitis (correct)
- Systemic lupus erythematosus
- Type 1 diabetes
What supported the diagnosis of PBC in the patient according to the AASLD guidelines?
What supported the diagnosis of PBC in the patient according to the AASLD guidelines?
- Low serum alkaline phosphatase levels
- Positive AMA, raised serum alkaline phosphatase, and bilirubin levels (correct)
- Normal bilirubin levels
- Negative AMA test
Who performed the liver transplantation procedure for the patient?
Who performed the liver transplantation procedure for the patient?
What is not known about PBC in childhood according to the text?
What is not known about PBC in childhood according to the text?
Why is there a need for more awareness regarding PBC in the pediatric age group?
Why is there a need for more awareness regarding PBC in the pediatric age group?
Which age group is predominantly affected by Primary Biliary Cirrhosis (PBC)?
Which age group is predominantly affected by Primary Biliary Cirrhosis (PBC)?
What is the approximate annual incidence of PBC?
What is the approximate annual incidence of PBC?
What is the role of anti-mitochondrial antibodies (AMA) in diagnosing PBC?
What is the role of anti-mitochondrial antibodies (AMA) in diagnosing PBC?
What is the initial autoimmune process in PBC that leads to the disease progression?
What is the initial autoimmune process in PBC that leads to the disease progression?
Why is it important to report further cases of PBC in the pediatric age group?
Why is it important to report further cases of PBC in the pediatric age group?
What is the outcome mentioned for the patient who underwent hepatic transplantation?
What is the outcome mentioned for the patient who underwent hepatic transplantation?
What are the four successive patho-morphologic stages of PBC?
What are the four successive patho-morphologic stages of PBC?
What are the criteria defined by the American Association for the Study of Liver Diseases (AASLD) for patients suspected to have PBC?
What are the criteria defined by the American Association for the Study of Liver Diseases (AASLD) for patients suspected to have PBC?
What is the hallmark histologic finding in PBC?
What is the hallmark histologic finding in PBC?
What is the FDA-approved medication for PBC patients?
What is the FDA-approved medication for PBC patients?
In the advanced stage of PBC, which treatment combinations can be considered along with Ursodeoxycholic acid?
In the advanced stage of PBC, which treatment combinations can be considered along with Ursodeoxycholic acid?
Why is staging with a needle biopsy rarely helpful in PBC?
Why is staging with a needle biopsy rarely helpful in PBC?
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