Podcast
Questions and Answers
What is the treatment of choice for PBC patients with end-stage liver disease?
What is the treatment of choice for PBC patients with end-stage liver disease?
Which autoimmune disease is a well-known cause of chronic liver disease in childhood?
Which autoimmune disease is a well-known cause of chronic liver disease in childhood?
What supported the diagnosis of PBC in the patient according to the AASLD guidelines?
What supported the diagnosis of PBC in the patient according to the AASLD guidelines?
Who performed the liver transplantation procedure for the patient?
Who performed the liver transplantation procedure for the patient?
Signup and view all the answers
What is not known about PBC in childhood according to the text?
What is not known about PBC in childhood according to the text?
Signup and view all the answers
Why is there a need for more awareness regarding PBC in the pediatric age group?
Why is there a need for more awareness regarding PBC in the pediatric age group?
Signup and view all the answers
Which age group is predominantly affected by Primary Biliary Cirrhosis (PBC)?
Which age group is predominantly affected by Primary Biliary Cirrhosis (PBC)?
Signup and view all the answers
What is the approximate annual incidence of PBC?
What is the approximate annual incidence of PBC?
Signup and view all the answers
What is the role of anti-mitochondrial antibodies (AMA) in diagnosing PBC?
What is the role of anti-mitochondrial antibodies (AMA) in diagnosing PBC?
Signup and view all the answers
What is the initial autoimmune process in PBC that leads to the disease progression?
What is the initial autoimmune process in PBC that leads to the disease progression?
Signup and view all the answers
Why is it important to report further cases of PBC in the pediatric age group?
Why is it important to report further cases of PBC in the pediatric age group?
Signup and view all the answers
What is the outcome mentioned for the patient who underwent hepatic transplantation?
What is the outcome mentioned for the patient who underwent hepatic transplantation?
Signup and view all the answers
What are the four successive patho-morphologic stages of PBC?
What are the four successive patho-morphologic stages of PBC?
Signup and view all the answers
What are the criteria defined by the American Association for the Study of Liver Diseases (AASLD) for patients suspected to have PBC?
What are the criteria defined by the American Association for the Study of Liver Diseases (AASLD) for patients suspected to have PBC?
Signup and view all the answers
What is the hallmark histologic finding in PBC?
What is the hallmark histologic finding in PBC?
Signup and view all the answers
What is the FDA-approved medication for PBC patients?
What is the FDA-approved medication for PBC patients?
Signup and view all the answers
In the advanced stage of PBC, which treatment combinations can be considered along with Ursodeoxycholic acid?
In the advanced stage of PBC, which treatment combinations can be considered along with Ursodeoxycholic acid?
Signup and view all the answers
Why is staging with a needle biopsy rarely helpful in PBC?
Why is staging with a needle biopsy rarely helpful in PBC?
Signup and view all the answers
