Pathophysiology of the Integumentary System: Dr. Elina Psara

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64 Questions

What is the primary function of carotene in the epidermis?

Providing protection against UV radiation

In which population group is melanin most dominant?

Dark-skinned humans

Which region of the body has the highest concentration of melanin?

Cheeks

What is the primary function of haemoglobin when bound to oxygen?

Transporting oxygen in the bloodstream

Which of the following is a primary function of the sweat glands?

Producing perspiration for evaporative cooling

Which type of tissue primarily makes up the dermis?

Strong, fibrous collagen

Where are melanocytes found in the skin?

Stratum basale

What is the primary function of the sebaceous glands?

Secretes lipid coating that lubricates hair shaft and epidermis

Which skin appendage serves as a protective agent against bacteria and lubricates the hair shaft?

Sebaceous glands

Which sweat gland type is primarily functional in early life and secretes mostly water and NaCl?

Eccrine glands

Which layer of the epidermis is responsible for protecting the skin against abrasion and penetration?

Stratum corneum

Where are Merkel cells predominantly found in the body?

Fingertips

What is the primary function of arrector pili muscles?

Insulating the body in cold conditions

What is the main function of Langerhan’s cells?

Help activate the adaptive immune system

What is the primary mode of secretion for eccrine sweat glands?

Secretion onto skin surface

What skin structure is made of hard keratin and grows from the nail matrix?

Nails

Which layer of the epidermis is visible only in thick skin?

Stratum lucidum

What causes dandruff on the scalp?

Excessive shedding of cells from the outer layer of skin

What determines the severity, morbidity, and mortality of burn injuries?

All of the above

Why does swimming in fresh water for an extended period cause epidermal swelling?

The hypotonic (freshwater) environment causes skin cells to swell.

What does a prolonged hypotension, infection, or edema lead to in the zone of stasis in burn injuries?

Necrosis occurs

Why do paper cuts hurt so bad but do not bleed?

The paper cuts damage nerve endings but not blood vessels.

A splinter that penetrates to the 3rd layer of the epidermis of the palm is lodged in which layer?

Stratum spinosum

Some criminals sand or cut skin off the tips of their fingers so as not to leave recognizable fingerprints. Would this practice permanently remove fingerprints? Why or why not.

No, because fingerprints are determined by underlying dermal ridges, not just the epidermal layer.

What is the thickness range of the skin (integument)?

0.5-3.0mm

What is the growth rate of nails?

0.1 mm/d

What is the average life span of scalp hair?

4 years

Which component comprises 12-15% of body weight?

Skin

What is the primary function of the integumentary system?

Protection

How does the skin protect from mechanical and chemical damage?

Barrier of tough, keratinized cells

What do pain receptors in the skin warn the body about?

Possible damage

What absorbs UV light and prevents it from reaching deeper layers?

Melanin

What is the process by which the skin helps cool down through sweating?

Evaporative cooling (sweating)

What is the process by which the skin helps warm up through increased blood flow?

Increased blood flow through skin (increases heat loss)

What is the primary function of Langerhan’s cells?

Sensory perception of light touch on the skin

Where are Merkel cells predominantly found in the body?

Around hair follicles in the dermis

What absorbs UV light and prevents it from reaching deeper layers?

Melanin

Which component comprises 12-15% of body weight?

Adipose tissue

What is the average life span of scalp hair?

5-7 years

Why do paper cuts hurt so bad but do not bleed?

Paper cuts activate pain receptors but do not penetrate blood vessels

Some criminals sand or cut skin off the tips of their fingers so as not to leave recognizable fingerprints. Would this practice permanently remove fingerprints? Why or why not?

No, it does not permanently remove fingerprints because they regenerate over time

What determines the severity, morbidity, and mortality of burn injuries?

Depth of the burn and body surface area affected

What is the process by which the skin helps warm up through increased blood flow?

Thermoregulation

What do pain receptors in the skin warn the body about?

Injury or potential tissue damage in the skin

What is the growth rate of nails?

2-3 mm per week

What causes dandruff on the scalp?

Fungal overgrowth due to scalp skin cell turnover

What is the average life span of scalp hair?

4 years

What is the primary mode of secretion for eccrine sweat glands?

Sweat

What do pain receptors in the skin warn the body about?

Potential injury

What is the primary function of carotene in the epidermis?

Providing color to skin

Which skin appendage serves as a protective agent against bacteria and lubricates the hair shaft?

Sebaceous glands

What causes dandruff on the scalp?

Blocked sebaceous glands

What absorbs UV light and prevents it from reaching deeper layers?

Melanin

What is the primary function of haemoglobin when bound to oxygen?

Transporting O2

What component comprises 12-15% of body weight?

Skin

Which layer of the epidermis is responsible for producing a lipid coating that lubricates the hair shaft and epidermis?

Stratum granulosum

What is the primary function of the hypodermis (subcutaneous layer) in the integumentary system?

Nourishes the epidermis

What is the major function of Merkel cells in the integumentary system?

Function as mechanoreceptors

Why does dandruff mainly consist of cells from the superficial layer of the skin on the scalp?

Accumulation of cells in the stratum corneum

What happens if a splinter penetrates to the 3rd layer of the epidermis of the palm?

Innervation provides sensation and initiates an immune response

What is the primary mode of secretion for sebaceous glands in the integumentary system?

Secrete lipid coating that lubricates the hair shaft and epidermis

Why does swimming in fresh water for an extended period cause epidermal swelling?

Freshwater is hypotonic, causing skin cells to swell with water

What function does sweating primarily serve in the integumentary system?

To regulate body temperature through evaporative cooling

What is the primary function of Langerhan’s cells in the integumentary system?

Help activate the adaptive immune system

Learn about the components and fun facts of the integumentary system, including the skin, hair, and nails. Understand its functions such as protection, sensation, thermoregulation, excretion of wastes, and synthesis of vitamin D.

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