Pathophysiology of Indigestion

Pathophysiology of Indigestion

• Infectious and non-infectious etiologies contribute to indigestion
• Gastric motility disorders can lead to indigestion
• Genetic factors play a role in the development of indigestion
• Visceral hypersensitivity and altered sensation can cause indigestion
• Psychosocial factors, such as stress, can exacerbate indigestion
• Certain drugs can trigger or worsen indigestion
• Environmental, dietary, and lifestyle factors, including ethanol, tobacco, and caffeine, can contribute to indigestion

Risk Factors for Indigestion

• Poor eating habits increase the risk of indigestion
• H. Pylori infection is a risk factor for indigestion
• Depression and anxiety can increase the risk of indigestion
• Use of analgesics (NSAIDs) can increase the risk of indigestion
• Tobacco, caffeine, and alcohol consumption can contribute to indigestion
• Pregnancy increases the risk of indigestion
• Obesity is a risk factor for indigestion

Differential Diagnosis of Indigestion

• GERD (Gastroesophageal Reflux Disease) can be mistaken for indigestion
• Functional Dyspepsia can be confused with indigestion
• Ulcer Disease may mimic indigestion
• Malignancy can be misdiagnosed as indigestion
• Opportunistic fungal or viral esophageal infections can be mistaken for indigestion
• Eosinophilic esophagitis can be misdiagnosed as indigestion