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Questions and Answers
What is one of the proposed pathophysiological mechanisms for age-related changes in smooth muscle?
What is one of the proposed pathophysiological mechanisms for age-related changes in smooth muscle?
- Reduced activity of muscarinic receptors in the detrusor smooth muscle
- Hyper-excitability of muscarinic receptors in the detrusor smooth muscle (correct)
- Increased activity of nicotinic receptors in the urothelium
- Decreased activity of adrenergic receptors in the neurovascular structures
Which structure shows hyper-excitability of muscarinic receptors according to the proposed pathophysiological mechanisms?
Which structure shows hyper-excitability of muscarinic receptors according to the proposed pathophysiological mechanisms?
- Neurovascular structures
- Sensory group C fibres
- Adrenergic receptors
- Detrusor smooth muscle (correct)
What contributes to atropine resistance according to the proposed pathophysiological mechanisms?
What contributes to atropine resistance according to the proposed pathophysiological mechanisms?
- Hyper-excitability of adrenergic receptors in the detrusor smooth muscle
- Increased afferent (sensory group C fibres) nerve activity (correct)
- Reduced activity of nicotinic receptors in the urothelium
- Decreased afferent (sensory group C fibres) nerve activity
Which level experiences denervation resulting in hyperactive voiding according to the proposed pathophysiological mechanisms?
Which level experiences denervation resulting in hyperactive voiding according to the proposed pathophysiological mechanisms?
What is the proposed pathophysiological mechanism for age-related changes in smooth muscle that leads to hyperactive voiding?
What is the proposed pathophysiological mechanism for age-related changes in smooth muscle that leads to hyperactive voiding?
Which structure exhibits hyper-excitability of muscarinic receptors based on the proposed pathophysiological mechanisms?
Which structure exhibits hyper-excitability of muscarinic receptors based on the proposed pathophysiological mechanisms?
What contributes to atropine resistance according to the proposed pathophysiological mechanisms?
What contributes to atropine resistance according to the proposed pathophysiological mechanisms?
