Pathopharma Daily Live Session: Cardiovascular System and Rheumatic Fever
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Questions and Answers

What is essential for the diagnosis of rheumatic fever according to the text?

  • Blood test for glucose levels
  • X-ray of the chest
  • Throat swab and antibiotic testing
  • ESR and CRP blood levels (correct)
  • Which one of the following is considered a major criterion for diagnosing rheumatic fever?

  • Raised WBC levels
  • Increased PR interval on ECG
  • Involvement of the heart (correct)
  • Arthralgia
  • Where are Ashoff nodules typically found in rheumatic heart disease?

  • Subcutaneous tissue
  • Endocardium
  • Myocardium (correct)
  • Pericardium
  • What will you find on the heart walls in rheumatic heart disease?

    <p>Vegetations</p> Signup and view all the answers

    What is NOT involved in the GAS criteria for diagnosing rheumatic fever?

    <p>MRI of the heart</p> Signup and view all the answers

    What is the most common valve affected in rheumatic fever?

    <p>Mitral valve</p> Signup and view all the answers

    What is the primary focus of Dr. Priyanka Sajdev's daily live session series?

    <p>Pathopharmacology for university exams</p> Signup and view all the answers

    What is the minimum number of pages required for a detailed response in long questions?

    <p>5 pages</p> Signup and view all the answers

    What is rheumatic fever, according to Dr. Priyanka?

    <p>A multi-system disease affecting five organs due to an autoimmune response</p> Signup and view all the answers

    How many major criteria are there for diagnosing rheumatic fever?

    <p>5 major criteria</p> Signup and view all the answers

    What is emphasized in the revised Jones criteria in 2016?

    <p>Need for a history of tonsillitis</p> Signup and view all the answers

    What is NOT a minor criterion for diagnosing rheumatic fever?

    <p>Respiratory rate</p> Signup and view all the answers

    Study Notes

    • Dr. Priyanka Sajdev is starting a daily live session series at 9:00 a.m. focusing on high-yield topics in pathopharma for university exams.
    • Today's topic is the cardiovascular system, specifically rheumatic fever and rheumatic heart disease.
    • In exams, questions can be direct (describing rheumatic fever) or indirect clinical questions related to the topic.
    • Short questions may range from 2 to 5 marks, while long questions require detailed responses of at least 5 pages.
    • Key short question topics include Jones criteria, Aschoff nodules, rheumatic carditis, and pancarditis.
    • Dr. Priyanka emphasizes the importance of understanding the distinction between rheumatic fever (an umbrella term) and rheumatic heart disease (one of the specific diseases under rheumatic fever).
    • Rheumatic fever is a multi-system disease affecting five organs due to an autoimmune response triggered by a streptococcus bacteria infection.
    • The five major criteria for diagnosing rheumatic fever include symptoms in the heart, brain, skin, subcutaneous tissue, and joints.
    • There are also minor criteria like fever, arthralgia, previous history of rheumatic fever, elevated ESR, CRP, and WBC count, and prolonged PR interval in ECG.
    • Dr. Priyanka introduces the concept of revised Jones criteria in 2016, which emphasizes the need for a history of tonsillitis in diagnosing rheumatic fever.- The text discusses the criteria for diagnosing rheumatic fever, including major and minor criteria.
    • Recurrent history of rheumatic fever, arthritis, raised blood levels of ESR, CRP, WBC, and increased PR interval on ECG are key factors in the diagnosis.
    • Throat swab, culture, and testing for anti-streptolysin O and anti-DNA antibodies are part of the GAS criteria for diagnosis.
    • Diagnosis requires at least two major criteria to be present, with the option of looking at minor criteria if only one major criterion is met.
    • The five major criteria for rheumatic fever involve the heart, brain, joints, skin, and subcutaneous tissue.
    • The four minor criteria include fever, arthralgia, raised blood levels of ESR, CRP, WBC, and increased PR interval on ECG.
    • GAS criteria involve throat swab, antibody testing, and are essential for diagnosis.
    • Rheumatic heart disease involves all three layers of the heart (endocardium, myocardium, pericardium).
    • Vegetations are nodules formed on the heart walls, known as vegetations in rheumatic heart disease.
    • MacCallan patch is a thick, rough patch found in the left atrium in rheumatic heart disease.
    • Ashoff nodules are granulomas found in the myocardium in rheumatic heart disease.
    • Fibrinous pericarditis causes a 'bread and butter' appearance in the pericardium.
    • Hormones involved in rheumatic fever include molecular mimicry and cross-reactivity.
    • The most common ball involved in rheumatic fever is the mitral valve.
    • Antihop cells are modified macrophages seen in rheumatic heart disease.
    • The speaker offers to help students with exam preparation and provides contact information for further assistance and guidance.
    • Students are encouraged to share the lecture content with their peers for wider benefit.
    • The speaker ends the session by wishing students success and emphasizing the importance of being a good human being before becoming a good doctor.

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    Description

    Join Dr. Priyanka Sajdev's daily live session series focusing on high-yield pathopharma topics for university exams, with today's topic being the cardiovascular system, specifically rheumatic fever and rheumatic heart disease. Explore key concepts like Jones criteria, Aschoff nodules, and distinctions between rheumatic fever and rheumatic heart disease.

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