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Questions and Answers
What is the study of structure and function of the body in disease?
What is the study of structure and function of the body in disease?
- Physiology
- Biochemistry
- Anatomy
- Pathology (correct)
What is the object of pathology?
What is the object of pathology?
- To acquaint the student with the changes occurring in tissues as the result of disease (correct)
- To study the symptoms of disease
- To develop treatment plans for disease
- To understand the causes of disease
What is the role of pathology in veterinary medicine?
What is the role of pathology in veterinary medicine?
- To study the causes of disease
- To develop treatment plans for disease
- To bridge basic science and clinical practice (correct)
- To diagnose diseases
What is the term for suffering or disease?
What is the term for suffering or disease?
What is the study of structure and function of the body in health?
What is the study of structure and function of the body in health?
What is the importance of studying pathology in veterinary medicine?
What is the importance of studying pathology in veterinary medicine?
What is the meaning of the term 'disease'?
What is the meaning of the term 'disease'?
What is the significance of pathology in correlating pre-pathology courses?
What is the significance of pathology in correlating pre-pathology courses?
Who is considered the most outstanding figure in European medicine after Galen and before Harvey?
Who is considered the most outstanding figure in European medicine after Galen and before Harvey?
At what age did Andreas Vesalius become a professor of anatomy at the University of Padua?
At what age did Andreas Vesalius become a professor of anatomy at the University of Padua?
Which century is often referred to as the century of anatomy?
Which century is often referred to as the century of anatomy?
Who described the blood vascular system and made the discovery of blood circulation?
Who described the blood vascular system and made the discovery of blood circulation?
How many different species of animals did William Harvey dissect to describe the vascular system?
How many different species of animals did William Harvey dissect to describe the vascular system?
What was the earlier name for 'artery' due to a mistaken belief?
What was the earlier name for 'artery' due to a mistaken belief?
What is the study of the origin and history of words and their meanings called?
What is the study of the origin and history of words and their meanings called?
What was the impact of William Harvey's discovery of blood circulation on pathology?
What was the impact of William Harvey's discovery of blood circulation on pathology?
What is the number of protons in the nucleus of an atom of oxygen?
What is the number of protons in the nucleus of an atom of oxygen?
How are electrons arranged in orbitals?
How are electrons arranged in orbitals?
What is the minimum number of electrons required in the inner orbital for an atom to be stable?
What is the minimum number of electrons required in the inner orbital for an atom to be stable?
What is the result of two atoms sharing electrons?
What is the result of two atoms sharing electrons?
What is the most stable electron configuration for an atom?
What is the most stable electron configuration for an atom?
What is the normal concentration of calcium in cytosol compared to extracellular calcium?
What is the normal concentration of calcium in cytosol compared to extracellular calcium?
What is the number of electrons in the outer orbital of an atom of oxygen?
What is the number of electrons in the outer orbital of an atom of oxygen?
Where is most of the intracellular calcium normally sequestered?
Where is most of the intracellular calcium normally sequestered?
Why does an atom of hydrogen react with another atom of hydrogen?
Why does an atom of hydrogen react with another atom of hydrogen?
What is the effect of ischaemia and toxins on cytosolic calcium concentration?
What is the effect of ischaemia and toxins on cytosolic calcium concentration?
What is the term for the group of atoms linked together by covalent bonds?
What is the term for the group of atoms linked together by covalent bonds?
What is activated by increased cytosolic calcium?
What is activated by increased cytosolic calcium?
What is the effect of phospholipases activated by increased cytosolic calcium?
What is the effect of phospholipases activated by increased cytosolic calcium?
What is the effect of proteases activated by increased cytosolic calcium?
What is the effect of proteases activated by increased cytosolic calcium?
What is the effect of ATPases activated by increased cytosolic calcium?
What is the effect of ATPases activated by increased cytosolic calcium?
Is loss of calcium homeostasis always a necessary preceding event in irreversible cell injury?
Is loss of calcium homeostasis always a necessary preceding event in irreversible cell injury?
What is a prion?
What is a prion?
What is the main difference between prions and viruses?
What is the main difference between prions and viruses?
What is the name of the protein that prions are made of?
What is the name of the protein that prions are made of?
Why are prions resistant to many agents that inactivate viruses?
Why are prions resistant to many agents that inactivate viruses?
Who won the Nobel Prize in Physiology and Medicine for discovering prions?
Who won the Nobel Prize in Physiology and Medicine for discovering prions?
What is the name of the diseases caused by prions in domestic animals and humans?
What is the name of the diseases caused by prions in domestic animals and humans?
What is the current phase of pathology?
What is the current phase of pathology?
What are diseases increasingly being explained by?
What are diseases increasingly being explained by?
Study Notes
Definition of Pathology
- Pathology is the study of the structure and function of the body in disease
- It deals with the structural and functional changes in cells, tissues, and organs that underlie disease
- Pathology bridges basic science and clinical practice
History of Pathology
- Andreas Vesalius (1514-1564) was a Belgian who made anatomy a living, working science
- William Harvey (1578-1657) described the blood vascular system and made the discovery of blood circulation in 1628
- Discovery of blood circulation had a significant impact on pathology and changed the course of medicine
- The 16th century is often called the century of anatomy
Prions
- Prions are proteinaceous infective particles that cause diseases in domestic animals and humans
- Prions lack nucleic acid (RNA or DNA) and do not produce inflammatory or immune reactions in the host
- Prions are resistant to many agents that normally inactivate viruses, such as ultraviolet light and standard disinfectants
- Stanley Prusiner discovered prions and won the 1997 Nobel Prize in Physiology and Medicine
Cell Injury and Cell Death
- Calcium homeostasis is maintained at extremely low concentrations in cytosol
- Intracellular calcium is sequestered in mitochondria and endoplasmic reticulum
- Ischaemia and toxins increase cytosolic calcium concentration, leading to cell injury and death
- Increased cytosolic calcium activates enzymes that cause membrane damage, protein breakdown, ATP depletion, and chromatin breakdown
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Description
This quiz covers the concept of pathology, the study of disease and its effects on the body's structure and function.