Pathology Quiz
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Questions and Answers

Which measurement increases in cases of Neural tube disorder?

  • Acetylcholinesterase (correct)
  • Phosphotidylinositol
  • Lecithin/sphingomyelin
  • Bilirubin
  • Which condition is often associated with Albuminuria?

  • Glomerulonephritis (correct)
  • Dehydration
  • Strenuous exercise
  • Cardiac failure
  • What type of effusion is typically seen in cases of UTI?

  • Inflammatory effusion
  • Exudative effusion (correct)
  • Hemorrhagic effusion
  • Transudative effusion
  • Is the presence of RBC in urine always pathologic?

    <p>False</p> Signup and view all the answers

    Which parasite is considered a 'true urinary parasite'?

    <p>S. haematobium</p> Signup and view all the answers

    Which type of urine sample is best suited for culture of urinary bacilli?

    <p>Mid-stream urine sample</p> Signup and view all the answers

    What type of transport involves a carrier?

    <p>Active transport</p> Signup and view all the answers

    What is the significance of the 'Diamond yellow sign'?

    <p>Instability</p> Signup and view all the answers

    Which of the following is a correctly matched pair?

    <p>Tyrosinuria - Rancid</p> Signup and view all the answers

    What is the Principle of 'protein error of indicator'?

    <p>Protein error of indicator</p> Signup and view all the answers

    What is the average volume of urine excreted by a normal adult within 24 hours?

    <p>1200ml</p> Signup and view all the answers

    Which type of cast cannot be found physiologically after strenuous exercise?

    <p>WBC cast</p> Signup and view all the answers

    Pyridium can cause a false positive reaction in which test?

    <p>Bilirubin</p> Signup and view all the answers

    What is the normal fecal color due to, except?

    <p>Bilirubin</p> Signup and view all the answers

    What is the ratio of velocity of light in the air over the velocity of light in the solution referred to as?

    <p>Refractive index</p> Signup and view all the answers

    What is detected by Polarizing Microscopy?

    <p>Crystals and lipids</p> Signup and view all the answers

    What is the cause of clay-colored stool?

    <p>Urobilinogen</p> Signup and view all the answers

    What is associated with kidney stones?

    <p>Uric acid</p> Signup and view all the answers

    What is the typical serum glucose level that corresponds to a CSF glucose level of 80 mg/dl?

    <p>120 mg/dl</p> Signup and view all the answers

    What is associated with ovarian tumors?

    <p>CA 125 positive, CEA negative</p> Signup and view all the answers

    What is the term for the presence of increased numbers of normal cells considered abnormal?

    <p>Pleocytosis</p> Signup and view all the answers

    Which of the following is NOT a pigment that can affect the color of urine?

    <p>NOTA</p> Signup and view all the answers

    What is the maximum amount of amniotic fluid that can be collected through amniocentesis?

    <p>30 mL</p> Signup and view all the answers

    What is the term for the smallest diameter of a type of tube?

    <p>Levine</p> Signup and view all the answers

    What is the test used to measure tubular secretion?

    <p>PSP test</p> Signup and view all the answers

    What is the term for the abnormal increase in urobilinogen and normal bilirubin?

    <p>Obstructive jaundice</p> Signup and view all the answers

    What is the term for a technique used to diagnose meningitis?

    <p>Limulus lysate</p> Signup and view all the answers

    What is the term for the appearance of oval fat bodies in the urine, indicative of?

    <p>Nephrotic syndrome</p> Signup and view all the answers

    What is the unit of measurement for creatine clearance?

    <p>mL/min</p> Signup and view all the answers

    What is the term for the thick-walled glass inserted in the rectum for stool collection?

    <p>Jellife tube</p> Signup and view all the answers

    What is the most common site of origin for seminal fluids?

    <p>Seminal vesicles</p> Signup and view all the answers

    What type of fat is typically found in urine?

    <p>Oval fat globules and free fat globules</p> Signup and view all the answers

    What is the principle of reagent strip automation?

    <p>Reflectance spectrophotometry</p> Signup and view all the answers

    What is the primary organic constituent of urine?

    <p>Urea</p> Signup and view all the answers

    What is the characteristic of the fluid leaving the glomerulus?

    <p>Specific gravity of 1.010</p> Signup and view all the answers

    What is the significance of the presence of triglycerides in urine?

    <p>Indicates a chylous or pseudochylous effusion</p> Signup and view all the answers

    What is the characteristic of bilirubin?

    <p>It is a degradation product of heme catabolism</p> Signup and view all the answers

    What is the characteristic of Tamm-Horsfall protein?

    <p>It is a protein found in the urine</p> Signup and view all the answers

    What is the characteristic of Urobilinogen?

    <p>It is a pigment found in the urine</p> Signup and view all the answers

    What is the characteristic of the CSF glucose level?

    <p>It is lower than the serum glucose level</p> Signup and view all the answers

    What is the normal volume of urine excreted by a normal adult within 24 hours?

    <p>1200mL</p> Signup and view all the answers

    Which type of cast cannot be found physiologically after strenuous exercise?

    <p>WBC cast</p> Signup and view all the answers

    What is the significance of Pyridium in a laboratory test?

    <p>Causes a false positive reaction in a bilirubin test</p> Signup and view all the answers

    What is the normal fecal color due to, except?

    <p>Bilirubin</p> Signup and view all the answers

    What is the ratio of velocity of light in the air over the velocity of light in the solution referred to as?

    <p>Refractive index</p> Signup and view all the answers

    What is detected by Polarizing Microscopy?

    <p>Crystals and lipids</p> Signup and view all the answers

    What is the cause of clay-colored stool?

    <p>Urobilinogen</p> Signup and view all the answers

    What is associated with kidney stones?

    <p>Uric acid</p> Signup and view all the answers

    What is the typical serum glucose level that corresponds to a CSF glucose level of 80 mg/dl?

    <p>120 mg/dl</p> Signup and view all the answers

    What is associated with ovarian tumors?

    <p>CA 125 and negative CEA</p> Signup and view all the answers

    What is the term for the abnormal increase in urobilinogen and normal bilirubin?

    <p>Hemolytic Anemia</p> Signup and view all the answers

    What is the test used to measure tubular secretion?

    <p>PSP Test</p> Signup and view all the answers

    What is the term for the appearance of oval fat bodies in the urine, indicative of?

    <p>Nephrotic Syndrome</p> Signup and view all the answers

    What is the unit of measurement for creatine clearance?

    <p>mL/min</p> Signup and view all the answers

    What is the term for the thick-walled glass inserted in the rectum for stool collection?

    <p>Jelliffe's Tube</p> Signup and view all the answers

    What is the maximum amount of amniotic fluid that can be collected through amniocentesis?

    <p>30 mL</p> Signup and view all the answers

    What is the term for the smallest diameter of a type of tube?

    <p>Levine's Diameter</p> Signup and view all the answers

    What is the term for the abnormal increase in WBCs in the urine?

    <p>Pyuria</p> Signup and view all the answers

    What is the term for the technique used to diagnose meningitis?

    <p>Limulus Lysate Test</p> Signup and view all the answers

    What is the term for the presence of increased numbers of normal cells considered abnormal?

    <p>Pleocytosis</p> Signup and view all the answers

    What is the significance of increased Acetylcholinesterase in amniotic fluid?

    <p>Neural tube disorder</p> Signup and view all the answers

    What is the term for the abnormal increase in urobilinogen and normal bilirubin?

    <p>Hemolytic jaundice</p> Signup and view all the answers

    Which of the following conditions is most likely to cause Albuminuria?

    <p>Glomerulonephritis</p> Signup and view all the answers

    What is the characteristic of exudative effusion?

    <p>High protein content</p> Signup and view all the answers

    What is the characteristic of the fluid leaving the glomerulus?

    <p>Specific gravity of 1.010</p> Signup and view all the answers

    What is the primary organic constituent of urine?

    <p>Urea</p> Signup and view all the answers

    What is the significance of RBC in urine?

    <p>Sometimes pathologic</p> Signup and view all the answers

    What is the principle of reagent strip automation?

    <p>Reflectance spectrophotometry</p> Signup and view all the answers

    What is the habitat of Schistosoma haematobium?

    <p>Urinary tract</p> Signup and view all the answers

    What is the characteristic of bilirubin?

    <p>Degradation product of heme catabolism</p> Signup and view all the answers

    What is the best type of urine sample for culture of urinary bacilli?

    <p>Midstream sample</p> Signup and view all the answers

    What is the characteristic of Tamm-Horsfall protein?

    <p>Found in urine</p> Signup and view all the answers

    What type of transport involves a carrier protein?

    <p>Active transport</p> Signup and view all the answers

    What is the significance of the Diamond yellow sign?

    <p>Instability</p> Signup and view all the answers

    What is the characteristic of Urobilinogen?

    <p>Found in urine</p> Signup and view all the answers

    What is the term for the appearance of oval fat bodies in the urine?

    <p>Steatorrhea</p> Signup and view all the answers

    What is the principle of protein error of indicator?

    <p>Protein interferes with indicator</p> Signup and view all the answers

    What is the effect of Alkaline Buffered pH on reagent strip?

    <p>False negative</p> Signup and view all the answers

    What is the significance of triglycerides in urine?

    <p>Indicates fat malabsorption</p> Signup and view all the answers

    What is the characteristic of the CSF glucose level?

    <p>Lower than serum glucose level</p> Signup and view all the answers

    Which of the following is NOT a characteristic of exudative effusion?

    <p>Transudative</p> Signup and view all the answers

    What is the significance of the presence of bilirubin in urine?

    <p>It indicates impaired liver function</p> Signup and view all the answers

    What is the most common site of origin for urinary parasites?

    <p>Bladder</p> Signup and view all the answers

    What is the principle of protein error of indicator?

    <p>The indicator reacts with the protein in the solution</p> Signup and view all the answers

    What type of cast is typically seen in cases of strenuous exercise?

    <p>None of the above</p> Signup and view all the answers

    What is the term for the presence of increased numbers of normal cells considered abnormal?

    <p>Hyperplasia</p> Signup and view all the answers

    Which of the following is NOT a pigment that can affect the color of urine?

    <p>Chlorophyll</p> Signup and view all the answers

    What is the maximum amount of amniotic fluid that can be collected through amniocentesis?

    <p>30-40 mL</p> Signup and view all the answers

    What is the term for the smallest diameter of a type of tube?

    <p>Caliber</p> Signup and view all the answers

    What is the test used to measure tubular secretion?

    <p>Phenolsulfonphthalein test</p> Signup and view all the answers

    What is the likely cause of a false positive reaction in a bilirubin test?

    <p>Pyridium</p> Signup and view all the answers

    Which of the following casts is not typically found in the urine after strenuous exercise?

    <p>WBC cast</p> Signup and view all the answers

    What is the normal fecal color due to?

    <p>Stercobilin and urobilin</p> Signup and view all the answers

    What is the ratio of velocity of light in the air over the velocity of light in the solution referred to as?

    <p>Refractive index</p> Signup and view all the answers

    What type of microscopy can detect crystals and lipids?

    <p>Polarizing microscopy</p> Signup and view all the answers

    What is the likely cause of a clay-colored stool?

    <p>Urobilinogen</p> Signup and view all the answers

    What is the primary laboratory test used to diagnose hemolytic anemia?

    <p>Flow cytometry</p> Signup and view all the answers

    What is associated with kidney stones?

    <p>Uric acid</p> Signup and view all the answers

    What is the term for the abnormal increase in urobilinogen and normal bilirubin?

    <p>Obstructive jaundice</p> Signup and view all the answers

    What is the typical serum glucose level that corresponds to a CSF glucose level of 80 mg/dl?

    <p>120 mg/dl</p> Signup and view all the answers

    What is associated with ovarian tumors?

    <p>CA 125 and negative CEA</p> Signup and view all the answers

    What is the unit of measurement for creatine clearance?

    <p>mL/min</p> Signup and view all the answers

    What is detected by the nitroso-naphthol test?

    <p>Tyrosinuria, maple syrup disease, and lead poisoning</p> Signup and view all the answers

    What is the term for the appearance of oval fat bodies in the urine, indicative of?

    <p>Nephrotic syndrome</p> Signup and view all the answers

    What is the test used to measure tubular secretion?

    <p>PSP test</p> Signup and view all the answers

    What is the maximum amount of amniotic fluid that can be collected through amniocentesis?

    <p>30 mL</p> Signup and view all the answers

    What is the term for the thick-walled glass inserted in the rectum for stool collection?

    <p>Jelliffe tube</p> Signup and view all the answers

    What is the characteristic of the CSF glucose level?

    <p>Lower than serum glucose level</p> Signup and view all the answers

    What is the term for the presence of increased numbers of normal cells considered abnormal?

    <p>Pleocytosis</p> Signup and view all the answers

    What is the term for the smallest diameter of a type of tube?

    <p>Levine tube</p> Signup and view all the answers

    What is the correlation of a positive test for bilirubin in strip testing with?

    <p>Urobilinogen</p> Signup and view all the answers

    What is the characteristic of the fluid leaving the glomerulus?

    <p>It has a specific gravity of 1.010</p> Signup and view all the answers

    What is the primary organic constituent of urine?

    <p>Urea</p> Signup and view all the answers

    What is the significance of triglycerides in urine?

    <p>It is a sign of steatorrhea</p> Signup and view all the answers

    What is the characteristic of bilirubin?

    <p>It is a degradation product of heme catabolism</p> Signup and view all the answers

    What is the principle of reagent strip automation?

    <p>Reflectance spectrophotometry</p> Signup and view all the answers

    What is the characteristic of Tamm-Horsfall protein?

    <p>It is a glycoprotein produced by the kidneys</p> Signup and view all the answers

    What is the characteristic of Urobilinogen?

    <p>It is a pigment produced by the breakdown of bilirubin</p> Signup and view all the answers

    What is the characteristic of the CSF glucose level?

    <p>It is lower than the serum glucose level</p> Signup and view all the answers

    What is the significance of the presence of 5-HIAA in urine?

    <p>It is a sign of carcinoid syndrome</p> Signup and view all the answers

    Study Notes

    Measurements in Neural Tube Disorders

    • Acetylcholinesterase measurement increases in case of Neural tube disorders

    Albuminuria

    • Albuminuria is more common in cases of glomerulonephritis, cardiac failure, strenuous exercise, and dehydration

    Effusions

    • Exudative effusions are more common in cases of infections, inflammations, malignancies, and hemorrhages

    Urine Analysis

    • Presence of RBCs in urine is always pathologic (FALSE)
    • Midstream urine is used for culture of urinary bacilli

    Transport Mechanisms

    • Active transport involves a carrier

    Diamond Yellow Sign

    • Indicates instability

    Tyrosinuria

    • Characterized by a rancid smell

    Principles of Protein

    • Protein error of indicator

    Urine Analysis

    • Alkaline buffered pH can cause false negative results in reagent strip tests

    Anticoagulants

    • Powdered EDTA is not acceptable for synovial fluid

    Urine Volume

    • Average volume of urine excreted by a normal adult within 24 hours is 1200 mL

    Urinary Casts

    • WBC cast cannot be found physiologically after strenuous exercise

    Interference in Tests

    • Pyridium can cause a false positive reaction in bilirubin tests

    Fecal Color

    • Normal fecal color is due to Stercobilin and Urobilin, but not Bilirubin

    Light

    • Refractive index is the ratio of velocity of light in air over the velocity of light in the solution

    Nitroso-naphthol Test

    • Used to screen for Tyrosinuria, Maple syrup disease, and Argentaffinoma

    Microscopy

    • Polarizing microscopy is used to detect crystals and lipids

    Clay Colored Stool

    • Caused by Urobilinogen

    Uric Acid

    • Associated with Gout

    Intestinal Perforation

    • ALP and amylase are increased in peritoneal fluid

    Sodium Nitroprusside

    • Tests for ketones

    Urine and Kidney

    • Ureter connects the kidney to the bladder

    WBCs in Urine

    • Not always indicative of bacterial infection

    HDN Testing

    • Zone I of Liley Graph indicates within normal limits

    Urine Analysis

    • Unpreserved urine collected at midnight and stored at room temperature will cause a decrease in glucose and ketones

    Diuretics

    • Can lead to polyuria

    CSF Glucose

    • If serum glucose is 120, CSF glucose is 80 mg/dL

    Peritoneal Fluid

    • CA 125 and negative CEA are associated with ovarian tumor

    Ketosis

    • Associated with Diabetes mellitus

    Tumor Markers

    • Increased cystine and melanin in urine are associated with tumors

    Urine pH

    • Clinically significant in detecting acid-base disorders and presence of crystals

    Ketones

    • Reagent strips react most strongly with Acetoacetic acid

    Organic Constituents

    • Both Creatinine and Urea are organic constituents of urine

    Urine Color

    • Orange color in urine indicates medication in UTI

    Hemolytic Anemia

    • Characterized by abnormally high Urobilinogen and normal bilirubin

    Flow Cytometry

    • Forward scatter indicates size

    Meningitis

    • Limulus lysate is used to diagnose gram-negative Meningitis

    Intestinal Perforation

    • ALP and amylase are increased in peritoneal fluid

    Prostate Infection

    • 3-glass collection, 3rd glass contains WBCs and bacteria, indicating prostate infection

    Crush Injury

    • Characterized by negative urine blood test and increased Urobilinogen

    Diabetes Insipidus

    • Specific gravity of urine is 1.005

    PSP Test

    • Used to measure Tubular Secretion

    Sperm Motility

    • Grade 3 indicates slow motility and lateral movement

    Creatine Clearance

    • Measured in mL/min

    Meconium

    • Greens discoloration of amniotic fluid

    Stool Collection

    • Jellife's thick-walled glass tube is used for stool collection

    RBCs in Urine

    • Dissolved with 10% HAc

    Nephrotic Syndrome

    • Characterized by oval fat bodies

    Cryptococcus

    • Detected in CSF using India ink/latex agglutination test

    Bence Jones Protein

    • Detected using electrophoresis

    Fetal Amniotic Fluid

    • Blood in fetal amniotic fluid may interfere with L/S ratio and foam stability

    Levines Rû, and Sawyer's Tubes

    • Smallest diameter is Levines

    Tyrosine

    • Forms fine needles that clump and rosette in severe liver disease

    Cryptococcus

    • Detected in CSF using India ink/latex agglutination test

    Amniotic Fluid

    • Maximum amount of amniotic fluid that can be collected through amniocentesis is 30 mL

    WBCs in Urine

    • Neutrophils are the most common WBCs found in urine

    End-Stage Renal Disease

    • Characterized by Isosthenuria, Electrolyte imbalance, and Azotemia

    Watson Schwartz Test

    • Used to detect Urobilinogen

    Ketone Bodies

    • Not positive after eating

    Pleocytosis

    • Presence of increased numbers of normal cells, considered abnormal

    Urine pH

    • Helpful in identifying some types of urine crystals

    CSF

    • Requires three tubes, and tube 2 is used for microbiological tests

    Urine Analysis

    • Urine specimen should be analyzed within 2 hours

    Gastric Tube

    • Smallest size is Levine's, and largest is Boa's (Edwald's)

    Synovial Fluid

    • Normal length of rope test is 4-6 cm

    Urine Analysis

    • Refractometry is used to measure specific gravity of urine

    Urinary Crystal Core

    • Constituent is Tamm-Horsfall protein

    Billirubin

    • Positive test in strip testing correlates with Urobilinogen

    Steatorrhea

    • Evaluated when droplets of large colored neutral fats are seen per HPF

    CSF Glucose

    • Lower than serum glucose

    Multiple Sclerosis

    • Characterized by Basic myelin protein and oligoclonal banding

    Urobilinogen

    • Classic Ehrlich reaction is based on the reaction of Urobilinogen with p-dimethylaminobenzaldehyde

    Feces Analysis

    • Clinitest and muscle fiber test are done, but not Iontophoresis pilocarpine

    Hoesch Reagent

    • Components include Ehrlich's in 6M HCL

    Synovial Fluid

    • RA cell (Ragocyte) is seen in synovial fluid

    Seminal Fluid

    • Majority originates from the seminal vesicles

    Bacterial Meningitis

    • Rapid presumptive diagnosis is done using Gram stain

    Crystals

    • pH of the urine is the most valuable aid in identifying crystals

    Automated Reagent Strips

    • Quality control is necessary

    hCG Levels

    • Not exhibited in ectopic pregnancy

    Bilirubin

    • Bilirubin is a degradation product of heme catabolism

    Fat in Urine

    • Oval fat globules and free fat globules are forms of fat found in urine

    Chylous and Pseudochylous Fluid

    • Differentiated using triglyceride

    Angiotensin II

    • Mechanism involves vasoconstriction of renal arterioles and release of aldosterone in adrenal cortex

    Renal Function

    • Tubular reabsorption is affected first in renal disease

    Reagent Strip Automation

    • Principle involves reflectance spectrophotometry

    Degree of Hydration

    • Specific gravity is used to determine the degree of hydration

    Calcium Oxalate

    • Described as octahedral with 2 diagonal lines like X

    Tumor Markers

    • Increased cystine and melanin in urine are associated with tumors

    Primary Organic Constituent

    • Urea is the primary organic constituent of urine

    Severity of Hemolysis

    • Plotted in zone 1 of Liley graph indicates within normal limits

    Fluid Leaving Glomerulus

    • Specific gravity is 1.010

    Urine Composition

    • Urea and creatinine are used to identify if it's really urine

    Albuminemia

    • Orthostatic proteinemia occurs while standing and stops with bed rest

    Hartnup's Disease

    • Characterized by metabolism of tryptophan

    Carcinoma

    • Enterochromaffin cells have increased urinary 5-HIAA

    Measurements in Neural Tube Disorders

    • Acetylcholinesterase measurement increases in case of Neural tube disorders

    Albuminuria

    • Albuminuria is more common in cases of glomerulonephritis, cardiac failure, strenuous exercise, and dehydration

    Effusions

    • Exudative effusions are more common in cases of infections, inflammations, malignancies, and hemorrhages

    Urine Analysis

    • Presence of RBCs in urine is always pathologic (FALSE)
    • Midstream urine is used for culture of urinary bacilli

    Transport Mechanisms

    • Active transport involves a carrier

    Diamond Yellow Sign

    • Indicates instability

    Tyrosinuria

    • Characterized by a rancid smell

    Principles of Protein

    • Protein error of indicator

    Urine Analysis

    • Alkaline buffered pH can cause false negative results in reagent strip tests

    Anticoagulants

    • Powdered EDTA is not acceptable for synovial fluid

    Urine Volume

    • Average volume of urine excreted by a normal adult within 24 hours is 1200 mL

    Urinary Casts

    • WBC cast cannot be found physiologically after strenuous exercise

    Interference in Tests

    • Pyridium can cause a false positive reaction in bilirubin tests

    Fecal Color

    • Normal fecal color is due to Stercobilin and Urobilin, but not Bilirubin

    Light

    • Refractive index is the ratio of velocity of light in air over the velocity of light in the solution

    Nitroso-naphthol Test

    • Used to screen for Tyrosinuria, Maple syrup disease, and Argentaffinoma

    Microscopy

    • Polarizing microscopy is used to detect crystals and lipids

    Clay Colored Stool

    • Caused by Urobilinogen

    Uric Acid

    • Associated with Gout

    Intestinal Perforation

    • ALP and amylase are increased in peritoneal fluid

    Sodium Nitroprusside

    • Tests for ketones

    Urine and Kidney

    • Ureter connects the kidney to the bladder

    WBCs in Urine

    • Not always indicative of bacterial infection

    HDN Testing

    • Zone I of Liley Graph indicates within normal limits

    Urine Analysis

    • Unpreserved urine collected at midnight and stored at room temperature will cause a decrease in glucose and ketones

    Diuretics

    • Can lead to polyuria

    CSF Glucose

    • If serum glucose is 120, CSF glucose is 80 mg/dL

    Peritoneal Fluid

    • CA 125 and negative CEA are associated with ovarian tumor

    Ketosis

    • Associated with Diabetes mellitus

    Tumor Markers

    • Increased cystine and melanin in urine are associated with tumors

    Urine pH

    • Clinically significant in detecting acid-base disorders and presence of crystals

    Ketones

    • Reagent strips react most strongly with Acetoacetic acid

    Organic Constituents

    • Both Creatinine and Urea are organic constituents of urine

    Urine Color

    • Orange color in urine indicates medication in UTI

    Hemolytic Anemia

    • Characterized by abnormally high Urobilinogen and normal bilirubin

    Flow Cytometry

    • Forward scatter indicates size

    Meningitis

    • Limulus lysate is used to diagnose gram-negative Meningitis

    Intestinal Perforation

    • ALP and amylase are increased in peritoneal fluid

    Prostate Infection

    • 3-glass collection, 3rd glass contains WBCs and bacteria, indicating prostate infection

    Crush Injury

    • Characterized by negative urine blood test and increased Urobilinogen

    Diabetes Insipidus

    • Specific gravity of urine is 1.005

    PSP Test

    • Used to measure Tubular Secretion

    Sperm Motility

    • Grade 3 indicates slow motility and lateral movement

    Creatine Clearance

    • Measured in mL/min

    Meconium

    • Greens discoloration of amniotic fluid

    Stool Collection

    • Jellife's thick-walled glass tube is used for stool collection

    RBCs in Urine

    • Dissolved with 10% HAc

    Nephrotic Syndrome

    • Characterized by oval fat bodies

    Cryptococcus

    • Detected in CSF using India ink/latex agglutination test

    Bence Jones Protein

    • Detected using electrophoresis

    Fetal Amniotic Fluid

    • Blood in fetal amniotic fluid may interfere with L/S ratio and foam stability

    Levines Rû, and Sawyer's Tubes

    • Smallest diameter is Levines

    Tyrosine

    • Forms fine needles that clump and rosette in severe liver disease

    Cryptococcus

    • Detected in CSF using India ink/latex agglutination test

    Amniotic Fluid

    • Maximum amount of amniotic fluid that can be collected through amniocentesis is 30 mL

    WBCs in Urine

    • Neutrophils are the most common WBCs found in urine

    End-Stage Renal Disease

    • Characterized by Isosthenuria, Electrolyte imbalance, and Azotemia

    Watson Schwartz Test

    • Used to detect Urobilinogen

    Ketone Bodies

    • Not positive after eating

    Pleocytosis

    • Presence of increased numbers of normal cells, considered abnormal

    Urine pH

    • Helpful in identifying some types of urine crystals

    CSF

    • Requires three tubes, and tube 2 is used for microbiological tests

    Urine Analysis

    • Urine specimen should be analyzed within 2 hours

    Gastric Tube

    • Smallest size is Levine's, and largest is Boa's (Edwald's)

    Synovial Fluid

    • Normal length of rope test is 4-6 cm

    Urine Analysis

    • Refractometry is used to measure specific gravity of urine

    Urinary Crystal Core

    • Constituent is Tamm-Horsfall protein

    Billirubin

    • Positive test in strip testing correlates with Urobilinogen

    Steatorrhea

    • Evaluated when droplets of large colored neutral fats are seen per HPF

    CSF Glucose

    • Lower than serum glucose

    Multiple Sclerosis

    • Characterized by Basic myelin protein and oligoclonal banding

    Urobilinogen

    • Classic Ehrlich reaction is based on the reaction of Urobilinogen with p-dimethylaminobenzaldehyde

    Feces Analysis

    • Clinitest and muscle fiber test are done, but not Iontophoresis pilocarpine

    Hoesch Reagent

    • Components include Ehrlich's in 6M HCL

    Synovial Fluid

    • RA cell (Ragocyte) is seen in synovial fluid

    Seminal Fluid

    • Majority originates from the seminal vesicles

    Bacterial Meningitis

    • Rapid presumptive diagnosis is done using Gram stain

    Crystals

    • pH of the urine is the most valuable aid in identifying crystals

    Automated Reagent Strips

    • Quality control is necessary

    hCG Levels

    • Not exhibited in ectopic pregnancy

    Bilirubin

    • Bilirubin is a degradation product of heme catabolism

    Fat in Urine

    • Oval fat globules and free fat globules are forms of fat found in urine

    Chylous and Pseudochylous Fluid

    • Differentiated using triglyceride

    Angiotensin II

    • Mechanism involves vasoconstriction of renal arterioles and release of aldosterone in adrenal cortex

    Renal Function

    • Tubular reabsorption is affected first in renal disease

    Reagent Strip Automation

    • Principle involves reflectance spectrophotometry

    Degree of Hydration

    • Specific gravity is used to determine the degree of hydration

    Calcium Oxalate

    • Described as octahedral with 2 diagonal lines like X

    Tumor Markers

    • Increased cystine and melanin in urine are associated with tumors

    Primary Organic Constituent

    • Urea is the primary organic constituent of urine

    Severity of Hemolysis

    • Plotted in zone 1 of Liley graph indicates within normal limits

    Fluid Leaving Glomerulus

    • Specific gravity is 1.010

    Urine Composition

    • Urea and creatinine are used to identify if it's really urine

    Albuminemia

    • Orthostatic proteinemia occurs while standing and stops with bed rest

    Hartnup's Disease

    • Characterized by metabolism of tryptophan

    Carcinoma

    • Enterochromaffin cells have increased urinary 5-HIAA

    Measurements in Neural Tube Disorders

    • Acetylcholinesterase measurement increases in case of Neural tube disorders

    Albuminuria

    • Albuminuria is more common in cases of glomerulonephritis, cardiac failure, strenuous exercise, and dehydration

    Effusions

    • Exudative effusions are more common in cases of infections, inflammations, malignancies, and hemorrhages

    Urine Analysis

    • Presence of RBCs in urine is always pathologic (FALSE)
    • Midstream urine is used for culture of urinary bacilli

    Transport Mechanisms

    • Active transport involves a carrier

    Diamond Yellow Sign

    • Indicates instability

    Tyrosinuria

    • Characterized by a rancid smell

    Principles of Protein

    • Protein error of indicator

    Urine Analysis

    • Alkaline buffered pH can cause false negative results in reagent strip tests

    Anticoagulants

    • Powdered EDTA is not acceptable for synovial fluid

    Urine Volume

    • Average volume of urine excreted by a normal adult within 24 hours is 1200 mL

    Urinary Casts

    • WBC cast cannot be found physiologically after strenuous exercise

    Interference in Tests

    • Pyridium can cause a false positive reaction in bilirubin tests

    Fecal Color

    • Normal fecal color is due to Stercobilin and Urobilin, but not Bilirubin

    Light

    • Refractive index is the ratio of velocity of light in air over the velocity of light in the solution

    Nitroso-naphthol Test

    • Used to screen for Tyrosinuria, Maple syrup disease, and Argentaffinoma

    Microscopy

    • Polarizing microscopy is used to detect crystals and lipids

    Clay Colored Stool

    • Caused by Urobilinogen

    Uric Acid

    • Associated with Gout

    Intestinal Perforation

    • ALP and amylase are increased in peritoneal fluid

    Sodium Nitroprusside

    • Tests for ketones

    Urine and Kidney

    • Ureter connects the kidney to the bladder

    WBCs in Urine

    • Not always indicative of bacterial infection

    HDN Testing

    • Zone I of Liley Graph indicates within normal limits

    Urine Analysis

    • Unpreserved urine collected at midnight and stored at room temperature will cause a decrease in glucose and ketones

    Diuretics

    • Can lead to polyuria

    CSF Glucose

    • If serum glucose is 120, CSF glucose is 80 mg/dL

    Peritoneal Fluid

    • CA 125 and negative CEA are associated with ovarian tumor

    Ketosis

    • Associated with Diabetes mellitus

    Tumor Markers

    • Increased cystine and melanin in urine are associated with tumors

    Urine pH

    • Clinically significant in detecting acid-base disorders and presence of crystals

    Ketones

    • Reagent strips react most strongly with Acetoacetic acid

    Organic Constituents

    • Both Creatinine and Urea are organic constituents of urine

    Urine Color

    • Orange color in urine indicates medication in UTI

    Hemolytic Anemia

    • Characterized by abnormally high Urobilinogen and normal bilirubin

    Flow Cytometry

    • Forward scatter indicates size

    Meningitis

    • Limulus lysate is used to diagnose gram-negative Meningitis

    Intestinal Perforation

    • ALP and amylase are increased in peritoneal fluid

    Prostate Infection

    • 3-glass collection, 3rd glass contains WBCs and bacteria, indicating prostate infection

    Crush Injury

    • Characterized by negative urine blood test and increased Urobilinogen

    Diabetes Insipidus

    • Specific gravity of urine is 1.005

    PSP Test

    • Used to measure Tubular Secretion

    Sperm Motility

    • Grade 3 indicates slow motility and lateral movement

    Creatine Clearance

    • Measured in mL/min

    Meconium

    • Greens discoloration of amniotic fluid

    Stool Collection

    • Jellife's thick-walled glass tube is used for stool collection

    RBCs in Urine

    • Dissolved with 10% HAc

    Nephrotic Syndrome

    • Characterized by oval fat bodies

    Cryptococcus

    • Detected in CSF using India ink/latex agglutination test

    Bence Jones Protein

    • Detected using electrophoresis

    Fetal Amniotic Fluid

    • Blood in fetal amniotic fluid may interfere with L/S ratio and foam stability

    Levines Rû, and Sawyer's Tubes

    • Smallest diameter is Levines

    Tyrosine

    • Forms fine needles that clump and rosette in severe liver disease

    Cryptococcus

    • Detected in CSF using India ink/latex agglutination test

    Amniotic Fluid

    • Maximum amount of amniotic fluid that can be collected through amniocentesis is 30 mL

    WBCs in Urine

    • Neutrophils are the most common WBCs found in urine

    End-Stage Renal Disease

    • Characterized by Isosthenuria, Electrolyte imbalance, and Azotemia

    Watson Schwartz Test

    • Used to detect Urobilinogen

    Ketone Bodies

    • Not positive after eating

    Pleocytosis

    • Presence of increased numbers of normal cells, considered abnormal

    Urine pH

    • Helpful in identifying some types of urine crystals

    CSF

    • Requires three tubes, and tube 2 is used for microbiological tests

    Urine Analysis

    • Urine specimen should be analyzed within 2 hours

    Gastric Tube

    • Smallest size is Levine's, and largest is Boa's (Edwald's)

    Synovial Fluid

    • Normal length of rope test is 4-6 cm

    Urine Analysis

    • Refractometry is used to measure specific gravity of urine

    Urinary Crystal Core

    • Constituent is Tamm-Horsfall protein

    Billirubin

    • Positive test in strip testing correlates with Urobilinogen

    Steatorrhea

    • Evaluated when droplets of large colored neutral fats are seen per HPF

    CSF Glucose

    • Lower than serum glucose

    Multiple Sclerosis

    • Characterized by Basic myelin protein and oligoclonal banding

    Urobilinogen

    • Classic Ehrlich reaction is based on the reaction of Urobilinogen with p-dimethylaminobenzaldehyde

    Feces Analysis

    • Clinitest and muscle fiber test are done, but not Iontophoresis pilocarpine

    Hoesch Reagent

    • Components include Ehrlich's in 6M HCL

    Synovial Fluid

    • RA cell (Ragocyte) is seen in synovial fluid

    Seminal Fluid

    • Majority originates from the seminal vesicles

    Bacterial Meningitis

    • Rapid presumptive diagnosis is done using Gram stain

    Crystals

    • pH of the urine is the most valuable aid in identifying crystals

    Automated Reagent Strips

    • Quality control is necessary

    hCG Levels

    • Not exhibited in ectopic pregnancy

    Bilirubin

    • Bilirubin is a degradation product of heme catabolism

    Fat in Urine

    • Oval fat globules and free fat globules are forms of fat found in urine

    Chylous and Pseudochylous Fluid

    • Differentiated using triglyceride

    Angiotensin II

    • Mechanism involves vasoconstriction of renal arterioles and release of aldosterone in adrenal cortex

    Renal Function

    • Tubular reabsorption is affected first in renal disease

    Reagent Strip Automation

    • Principle involves reflectance spectrophotometry

    Degree of Hydration

    • Specific gravity is used to determine the degree of hydration

    Calcium Oxalate

    • Described as octahedral with 2 diagonal lines like X

    Tumor Markers

    • Increased cystine and melanin in urine are associated with tumors

    Primary Organic Constituent

    • Urea is the primary organic constituent of urine

    Severity of Hemolysis

    • Plotted in zone 1 of Liley graph indicates within normal limits

    Fluid Leaving Glomerulus

    • Specific gravity is 1.010

    Urine Composition

    • Urea and creatinine are used to identify if it's really urine

    Albuminemia

    • Orthostatic proteinemia occurs while standing and stops with bed rest

    Hartnup's Disease

    • Characterized by metabolism of tryptophan

    Carcinoma

    • Enterochromaffin cells have increased urinary 5-HIAA

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    Description

    A set of multiple-choice questions covering various topics in pathology, including neural tube disorders, albuminuria, and effusions.

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