Pathogenesis of Osteoarthritis and Rheumatoid Arthritis Quiz

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Questions and Answers

Which of the following best describes eburnation in the context of joint pathology?

  • Formation of new bone at a joint
  • Inflammation of the synovial membrane
  • Bone articulating against bone (correct)
  • Degradation of cartilage by proteolytic enzymes

What is a common autoimmune characteristic of Rheumatoid Arthritis?

  • Presence of autoantibodies to IgG (correct)
  • Weakness and low-grade fever
  • Elevated levels of C-reactive protein
  • Enlargement of joints due to synovitis

Which laboratory test can be used to detect the specific antibody in the blood associated with Rheumatoid Arthritis?

  • Blood test
  • X-ray
  • ESR
  • Anti-citrullinated Protein Antibodies (ACPAs) (correct)

What is a common clinical feature of advanced Rheumatoid Arthritis?

<p>Enlargement of joints due to synovitis (C)</p> Signup and view all the answers

Which of the following is NOT a clinical feature of Osteoarthritis (OA)?

<p>Swelling and redness around the affected joint (D)</p> Signup and view all the answers

In the lab diagnosis of Rheumatoid Arthritis (RA), what do the articular surfaces appear as in an X-ray?

<p>Close together (B)</p> Signup and view all the answers

Which of the following is true about the pathogenesis of Osteoarthritis?

<p>Increased loss of articular cartilage (C)</p> Signup and view all the answers

What is a characteristic feature of Rheumatoid Arthritis in terms of its autoimmune nature?

<p>Immune system attacks synovial tissue (C)</p> Signup and view all the answers

Which of the following best describes the characteristic early lesion seen in Rheumatoid Arthritis?

<p>Sheet of inflammatory granulation tissue invading the joint (C)</p> Signup and view all the answers

Which laboratory investigation is commonly used in the diagnosis of Rheumatoid Arthritis?

<p>Presence of anti-cyclic citrullinated peptide (anti-CCP) antibodies (C)</p> Signup and view all the answers

What autoimmune component is believed to play a significant role in the pathogenesis of Rheumatoid Arthritis?

<p>Production of autoantibodies against joint proteins (B)</p> Signup and view all the answers

Which of the following is a common clinical feature of Rheumatoid Arthritis?

<p>Worsening symptoms in cold weather (A)</p> Signup and view all the answers

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