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Pathogenesis of Osteoarthritis and Rheumatoid Arthritis Quiz

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Pathogenesis of Osteoarthritis and Rheumatoid Arthritis Quiz

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Questions and Answers

Which of the following best describes eburnation in the context of joint pathology?

Formation of new bone at a joint

Inflammation of the synovial membrane

Bone articulating against bone (correct)

Degradation of cartilage by proteolytic enzymes

What is a common autoimmune characteristic of Rheumatoid Arthritis?

Presence of autoantibodies to IgG (correct)

Weakness and low-grade fever

Elevated levels of C-reactive protein

Enlargement of joints due to synovitis

Which laboratory test can be used to detect the specific antibody in the blood associated with Rheumatoid Arthritis?

Blood test

X-ray

ESR

Anti-citrullinated Protein Antibodies (ACPAs) (correct)

What is a common clinical feature of advanced Rheumatoid Arthritis?

Enlargement of joints due to synovitis Signup and view all the answers

Which of the following is NOT a clinical feature of Osteoarthritis (OA)?

Swelling and redness around the affected joint Signup and view all the answers

In the lab diagnosis of Rheumatoid Arthritis (RA), what do the articular surfaces appear as in an X-ray?

Close together Signup and view all the answers

Which of the following is true about the pathogenesis of Osteoarthritis?

Increased loss of articular cartilage Signup and view all the answers

What is a characteristic feature of Rheumatoid Arthritis in terms of its autoimmune nature?

Immune system attacks synovial tissue Signup and view all the answers

Which of the following best describes the characteristic early lesion seen in Rheumatoid Arthritis?

Sheet of inflammatory granulation tissue invading the joint Signup and view all the answers

Which laboratory investigation is commonly used in the diagnosis of Rheumatoid Arthritis?

Presence of anti-cyclic citrullinated peptide (anti-CCP) antibodies Signup and view all the answers

What autoimmune component is believed to play a significant role in the pathogenesis of Rheumatoid Arthritis?

Production of autoantibodies against joint proteins Signup and view all the answers

Which of the following is a common clinical feature of Rheumatoid Arthritis?

Worsening symptoms in cold weather Signup and view all the answers