Pathogenesis of Osteoarthritis and Rheumatoid Arthritis Quiz

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12 Questions

Which of the following best describes eburnation in the context of joint pathology?

Bone articulating against bone

What is a common autoimmune characteristic of Rheumatoid Arthritis?

Presence of autoantibodies to IgG

Which laboratory test can be used to detect the specific antibody in the blood associated with Rheumatoid Arthritis?

Anti-citrullinated Protein Antibodies (ACPAs)

What is a common clinical feature of advanced Rheumatoid Arthritis?

Enlargement of joints due to synovitis

Which of the following is NOT a clinical feature of Osteoarthritis (OA)?

Swelling and redness around the affected joint

In the lab diagnosis of Rheumatoid Arthritis (RA), what do the articular surfaces appear as in an X-ray?

Close together

Which of the following is true about the pathogenesis of Osteoarthritis?

Increased loss of articular cartilage

What is a characteristic feature of Rheumatoid Arthritis in terms of its autoimmune nature?

Immune system attacks synovial tissue

Which of the following best describes the characteristic early lesion seen in Rheumatoid Arthritis?

Sheet of inflammatory granulation tissue invading the joint

Which laboratory investigation is commonly used in the diagnosis of Rheumatoid Arthritis?

Presence of anti-cyclic citrullinated peptide (anti-CCP) antibodies

What autoimmune component is believed to play a significant role in the pathogenesis of Rheumatoid Arthritis?

Production of autoantibodies against joint proteins

Which of the following is a common clinical feature of Rheumatoid Arthritis?

Worsening symptoms in cold weather

Test your knowledge on the pathogenesis of osteoarthritis and rheumatoid arthritis, including topics like eburnation, joint replacement, NSAIDs, and autoimmune nature of RA. Explore the key concepts related to these common joint diseases.

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