5 Questions
What is the primary mediator of the febrile response?
Cytokines
In fever, what causes the body to increase heat production and decrease heat loss?
Elevated set point due to endogenous pyrogens
What constitutes the clearest and strongest evidence in favor of the protective role of fever?
Production of fever simultaneously with lymphocyte activation
What can lead to harmful and even lethal effects during fever generation?
Overproduction of cytokines
What is the optimal temperature for the protective processes of the immune response?
Around 39.5 °C
Test your knowledge of the core messages related to the pathogenesis of fever, including common causes, cytokine mediation, and the role of endogenous pyrogens.
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