30 Questions
Which classification of anemia can occur due to infection with Plasmodium?
Hemolytic anemia
Which viral infection can cause hemolytic and/or autoimmune hemolytic anemia?
HIV
Which chronic illness is associated with anemia of chronic disease?
Rheumatoid arthritis
Which bacterial infection suppresses erythropoietin (EPO) production and the proliferation of erythroid progenitors?
Clostridium perfringens
Which infection can lead to acute anemia?
Hookworm
Which of the following is a characteristic of Parvoviridae?
Non-enveloped virion
Which cell type is the primary target for Parvovirus B19?
Erythroid precursor cells
Which of the following is a clinical manifestation of Parvovirus B19 infection?
Erythema infectiosum
Which type of anemia can occur in individuals with high red blood cell turnover and Parvovirus B19 infection?
Transient Aplastic Crisis
Which population is at risk for developing chronic Parvovirus B19 infection and severe anemia?
Immunocompromised individuals
Which virus is associated with transient aplastic crisis (TAC) in patients with underlying hemolytic disorders or high RBC turnover?
Parvovirus B19
What is the diagnostic test of choice to detect viremia in immunodeficient patients with chronic Parvovirus B19 infection?
PCR
Which protozoan causes anemia by rupturing infected red blood cells (RBCs) and interfering with the production of erythropoietin?
Plasmodium falciparum
What is the vector for Babesia microti, a tick-transmitted protozoan that causes hemolytic anemia?
Tick (Ixodes scapularis)
What are the cellular targets for Parvovirus B19?
Red blood cells
Which type of helminth causes microcytic hypochromic anemia?
Nematode
What is the main mechanism of developing microcytic hypochromic anemia in A. duodenale and N. americanus infection?
Iron deficiency
Which helminth infection can lead to megaloblastic anemia?
D. latum infection
What is the main mechanism of developing megaloblastic anemia in D. latum infection?
Impaired B12 absorption
What are the main symptoms of megaloblastic anemia due to D. latum infection?
Fatigue and weight loss
Which type of anemia is characterized by the bone marrow producing unusually large, structurally abnormal, immature red blood cells?
Megaloblastic anemia
Which type of anemia is associated with decreased iron reserves in the body?
Microcytic anemia
Which type of anemia is characterized by the abnormal breakdown of red blood cells?
Hemolytic anemia
Which type of anemia is associated with a deficiency of all three blood cell types (red blood cells, white blood cells, and platelets)?
Aplastic anemia
Which type of anemia is caused by the body's immune system creating antibodies directed at red blood cell surface proteins?
Autoimmune hemolytic anemia
Which bacterial species causes severe anemia and is transmitted by sandfly bite in the Andes mountain region of Peru, Ecuador, and Colombia?
Bartonella bacilliformis
Which bacterium is known for causing epiglottitis and meningitis, and often colonizes the upper respiratory tract?
Haemophilus influenzae B
Which bacterium is ubiquitous in soil, water, and sewage, and is a normal microbial flora of the GI tract of animals and humans?
Clostridium perfringens
Which bacterium is associated with cellulitis, fasciitis, and myonecrosis, and produces toxins that degrade the phospholipids of the red cell membrane bilayer?
Clostridium perfringens
Which bacterium is a Gram-positive anaerobic rod, and is often found along with facultative or aerobic organisms in infections?
Bacillus cereus
Test your knowledge on the pathogenesis and immunity of Parvovirus B19, including its effects on cellular targets and the clinical syndrome variation in different hosts.
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