Podcast
Questions and Answers
Which of the following best encapsulates the role of lipids within cells?
Which of the following best encapsulates the role of lipids within cells?
- Primarily responsible for catalyzing enzymatic reactions related to ATP production.
- Act solely as precursors for protein synthesis.
- Function as structural components of cellular membranes, energy storage, and signaling molecules. (correct)
- Serve exclusively as structural components of the cytoskeleton.
In the context of cellular respiration, how does anaerobic respiration differ fundamentally from aerobic respiration?
In the context of cellular respiration, how does anaerobic respiration differ fundamentally from aerobic respiration?
- Anaerobic respiration occurs in the absence of oxygen, while aerobic respiration requires oxygen. (correct)
- Anaerobic respiration involves the use of oxygen as the final electron acceptor, while aerobic respiration does not.
- Anaerobic respiration occurs exclusively in mitochondria, whereas aerobic respiration takes place in the cytoplasm.
- Anaerobic respiration produces significantly more ATP per glucose molecule than aerobic respiration.
How do catabolic and anabolic processes interrelate within cellular metabolism?
How do catabolic and anabolic processes interrelate within cellular metabolism?
- Catabolism and anabolism operate independently, each fulfilling distinct cellular needs without interaction.
- Catabolism provides complex molecules necessary for anabolism.
- Anabolism breaks down molecules to release energy, while catabolism utilizes energy to synthesize molecules.
- Catabolism releases energy by breaking down complex molecules, which anabolism then utilizes to build complex molecules. (correct)
What role is played by enzymes in the context of glycolysis?
What role is played by enzymes in the context of glycolysis?
What crucial enzymatic activity is carried out by isomerase during glycolysis?
What crucial enzymatic activity is carried out by isomerase during glycolysis?
Which statement accurately describes the significance of glycolysis across various tissue types?
Which statement accurately describes the significance of glycolysis across various tissue types?
Considering the regulation of glycolysis, how does glucose-6-phosphate (G-6-P) exert its regulatory influence?
Considering the regulation of glycolysis, how does glucose-6-phosphate (G-6-P) exert its regulatory influence?
How is the energy released by the electron transport chain primarily harnessed to produce ATP?
How is the energy released by the electron transport chain primarily harnessed to produce ATP?
What distinguishes the inner mitochondrial membrane from the outer mitochondrial membrane in terms of function and composition?
What distinguishes the inner mitochondrial membrane from the outer mitochondrial membrane in terms of function and composition?
In the context of the pentose phosphate pathway, what is the primary metabolic rationale for the oxidative phase?
In the context of the pentose phosphate pathway, what is the primary metabolic rationale for the oxidative phase?
Under what metabolic conditions is the pentose phosphate pathway most actively utilized within cells?
Under what metabolic conditions is the pentose phosphate pathway most actively utilized within cells?
Consider a scenario where the electron transport chain is inhibited. Which of the following would most directly be affected?
Consider a scenario where the electron transport chain is inhibited. Which of the following would most directly be affected?
How does the redox potential change as electrons move through the electron transport chain?
How does the redox potential change as electrons move through the electron transport chain?
How does the process of oxidative phosphorylation depend directly on the electron transport chain?
How does the process of oxidative phosphorylation depend directly on the electron transport chain?
What role does ubiquinone (coenzyme Q) play in the electron transport chain?
What role does ubiquinone (coenzyme Q) play in the electron transport chain?
Flashcards
Cytosol
Cytosol
A liquid located inside cells, making up the majority of intracellular fluid.
Complex I (NADH dehydrogenase)
Complex I (NADH dehydrogenase)
Transfers electrons from NADH to ubiquinone. Redox potential: -0.32 V.
Complex II (Succinate dehydrogenase)
Complex II (Succinate dehydrogenase)
Transfers electrons from succinate to ubiquinone. Redox potential: +0.83V.
Ubiquinone (Coenzyme Q)
Ubiquinone (Coenzyme Q)
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Cytochrome c
Cytochrome c
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Complex IV (Cytochrome c oxidase)
Complex IV (Cytochrome c oxidase)
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Complex III (Cytochrome bc1)
Complex III (Cytochrome bc1)
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Coupling of Respiratory Chain with Oxidative Phosphorylation
Coupling of Respiratory Chain with Oxidative Phosphorylation
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Oxidative Phosphorylation
Oxidative Phosphorylation
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Outer Mitochondrial Membrane
Outer Mitochondrial Membrane
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Inner Mitochondrial Membrane
Inner Mitochondrial Membrane
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Intermembrane Space
Intermembrane Space
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Mitochondrial Matrix
Mitochondrial Matrix
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Metabolism of Carbohydrates
Metabolism of Carbohydrates
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Glycolysis
Glycolysis
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Study Notes
Partial Differential Equations
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A partial differential equation (PDE) contains unknown multivariable functions and their partial derivatives.
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General form: $F(x, y, u, u_x, u_y, u_{xx}, u_{yy}, u_{xy},...) = 0$, where $x, y$ are independent variables, $u = u(x, y)$ is a dependent variable, $u_x, u_y$ are first order partial derivatives, $u_{xx}, u_{yy}, u_{xy}$ are second order partial derivatives, and $F$ is a function.
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Examples:
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Advection Equation: $\frac{\partial u}{\partial t} + c \frac{\partial u}{\partial x} = 0$
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Heat Equation: $\frac{\partial u}{\partial t} = \alpha \frac{\partial^2 u}{\partial x^2}$
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Wave Equation: $\frac{\partial^2 u}{\partial t^2} = c^2 \frac{\partial^2 u}{\partial x^2}$
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Laplace Equation: $\frac{\partial^2 u}{\partial x^2} + \frac{\partial^2 u}{\partial y^2} = 0$
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Poisson Equation: $\frac{\partial^2 u}{\partial x^2} + \frac{\partial^2 u}{\partial y^2} = f(x, y)$
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The order of a PDE is determined by the highest order derivative in the equation.
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Examples:
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$\frac{\partial u}{\partial t} + c \frac{\partial u}{\partial x} = 0$ (First Order)
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$\frac{\partial^2 u}{\partial t^2} = c^2 \frac{\partial^2 u}{\partial x^2}$ (Second Order)
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A PDE is linear if the dependent variable and its derivatives appear linearly; otherwise, it is nonlinear.
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Examples:
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Linear PDE: $\frac{\partial u}{\partial t} = \alpha \frac{\partial^2 u}{\partial x^2}$
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Nonlinear PDE: $\frac{\partial u}{\partial t} + u \frac{\partial u}{\partial x} = 0$ (Burger's Equation)
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A solution to a PDE is a function that satisfies the equation, and can be general or particular.
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To obtain a unique solution, boundary conditions (BCs) and initial conditions (ICs) are often required.
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Types of Boundary Conditions:
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Dirichlet BC: Specifies the value of the solution; $u(x, t) = f(t)$ on boundary
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Neumann BC: Specifies the value of the normal derivative; $\frac{\partial u}{\partial x}(x, t) = g(t)$ on boundary
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Robin BC: A combination of Dirichlet and Neumann conditions; $\alpha u(x, t) + \beta \frac{\partial u}{\partial x}(x, t) = h(t)$ on boundary
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Methods for Solving PDEs:
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Analytical Methods: Separation of variables, method of characteristics, etc.
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Numerical Methods: Finite difference method, finite element method, finite volume method, etc.
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A general second-order linear PDE in two independent variables: $Au_{xx} + Bu_{xy} + Cu_{yy} + Du_x + Eu_y + Fu = G$, where $A, B, C, D, E, F, G$ are functions of $x$ and $y$.
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The discriminant $\Delta = B^2 - 4AC$ is for classification.
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PDE Classification based on Discriminant:
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Hyperbolic: $\Delta > 0$ (e.g., Wave Equation)
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Parabolic: $\Delta = 0$ (e.g., Heat Equation)
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Elliptic: $\Delta < 0$ (e.g., Laplace Equation)
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Applications of PDEs include: heat transfer, fluid dynamics, electromagnetism, quantum mechanics, wave propogation and financial modeling.
Numerische Integration
- The objective is to calculate definite integrals: $I[f] = \int_a^b f(x) dx$
- Achieved through quadrature formulas: $Q[f] = \sum_{i=0}^n w_i f(x_i)$
- $x_i$: Nodes
- $w_i$: Weights
- Newton-Cotes Formulas: $f$ is replaced by an interpolation polynomial $p_n$ and integrated
- $I[f] = \int_a^b f(x) dx \approx \int_a^b p_n(x) dx =: Q[f]$
- Derivation:
- $x_0, \dots, x_n \in [a, b]$ are pairwise distinct, and $p_n$ is the interpolation polynomial for $f$, i.e., $p_n(x) = \sum_{i=0}^n f(x_i) L_i(x)$
- $L_i$ are the Lagrange fundamental polynomials: $L_i(x) = \prod_{\substack{k=0 \ k \neq i}}^n \frac{x - x_k}{x_i - x_k}$
- $Q[f] = \int_a^b p_n(x) dx = \int_a^b \sum_{i=0}^n f(x_i) L_i(x) dx = \sum_{i=0}^n \underbrace{\int_a^b L_i(x) dx}_{=: w_i} f(x_i)$
- The weights, $w_i = \int_a^b L_i(x) dx$, do not depend on $f$!
- Knots, $x_i$, are fixed.
- For the Newton-Cotes formulas, the nodes $x_i$ are equidistant: $x_i = a + i \cdot h, \quad i = 0, \dots, n \quad \text{with} \quad h = \frac{b-a}{n}$.
- Examples of Newton-Cotes Formulas:
- $n = 0: \quad x_0 = a + \frac{h}{2} = \frac{a + b}{2}$ (Midpoint Rule)
- $Q[f] = (b - a) f(\frac{a + b}{2})$
- $n = 1: \quad x_0 = a, \quad x_1 = b$ (Trapezoidal Rule)
- $Q[f] = \frac{b - a}{2} (f(a) + f(b))$
- $n = 2: \quad x_0 = a, \quad x_1 = \frac{a + b}{2}, \quad x_2 = b$ (Simpson's Rule)
- $Q[f] = \frac{b - a}{6} (f(a) + 4f(\frac{a + b}{2}) + f(b))$
Algèbre Linéaire
- An space vector on a field is a set E with two operations that must satisfy eight axioms.
- Addition Vectorielle
- $E \times E \rightarrow E$, notée $(u, v) \mapsto u + v$
- Multiplication scalaire
- $\mathbb{K} \times E \rightarrow E$, notée $(\lambda, u) \mapsto \lambda u$
- Associativity of Addition: $(u + v) + w = u + (v + w)$ for all $u, v, w \in E$
- Commutativity of Addition: $u + v = v + u$ for all $u, v \in E$
- Existence of Neutral Element: There is a 0 such that $u + 0 = u$ for all u in E.
- Existence of Additive Inverse: For all $u \in E$, there is $-u \in E$ such that $u + (-u) = 0$.
- Compatibility of Scalar Multiplication: $\lambda(\mu u) = (\lambda \mu)u$ for all scalars $\lambda, \mu$ and vectors $u$.
- Distributivity over Vector Addition: $\lambda(u + v) = \lambda u + \lambda v$ for all scalars $\lambda$ and vectors $u, v$.
- Distributivity over Scalar Addition: $(\lambda + \mu)u = \lambda u + \mu u$ for all scalars $\lambda, \mu$ and vectors $u$.
- Identity for Scalar Multiplication: $1u = u$ for all vectors $u$.
- Examples include:
- $\mathbb{R}^n$ is a vector space on $\mathbb{R}$.
- $\mathbb{C}^n$ is a vector space on $\mathbb{C}$ and $\mathbb{R}$.
- The set of continuous fonctions de $\mathbb{R}$ in $\mathbb{R}$, noté $C(\mathbb{R}, \mathbb{R})$
- The set of ponynomials, noté $\mathbb{R}[X]$, is a vector space on $\mathbb{R}$
- A set F of and vector space E is a subspace if: stable by addition, stable by scalar multiplication
- Combination Linéaires: $\lambda_1 u_1 + \lambda_2 u_2 +... + \lambda_n u_n$ where $\lambda_1, \lambda_2,..., \lambda_n$ are des scalaires
- Space Engendré: $Vect(S)$,is the set of all combinasion linéaires, un sous-space vectoriel of $E$
- Linear Independence: $\lambda_1 u_1 + \lambda_2 u_2 +... + \lambda_n u_n = 0$, implique $\lambda_1 = \lambda_2 =... = \lambda_n = 0$
- Base d'un espace vectoriel: linearly independent and générateur de $E$
- Dimension d'un espace vectoriel: If E admet une base finie, of dimension finie.
Corporate Social Responsibility
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The thesis examined CSR's impact on financial performance, focusing on customer satisfaction as a mediator.
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The study employed a quantitative approach, using data from various industries.
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Key findings:
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CSR initiatives positively and significantly affect financial performance.
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Customer satisfaction partially mediates the CSR-financial performance relationship.
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The impact of CSR is stronger in industries with high customer interaction.
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Theoretical Implications: The research adds to literature by providing evidence for customer satisfaction's role in CSR's impact on financial performance. It notes the importance of industry-specific contexts.
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Managerial Implications: Managers should consider CSR investments, customer satisfaction and tailor CSR strategies to their specific industry.
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Limitations: The study had a relatively small sample size, relied on secondary data, and focused on few CSR dimensions.
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Future Research: Larger and more diverse samples, primary data collection, examining CSR dimensions, moderating role exploration (firm size, ownership structure), and longitudinal data are needed for future investigations.
Linear Programming - Duality
- Primal problem:
max c^T x
s.t. Ax = 0
- Dual problem:
min b^T y
s.t. A^T y >= c
y >= 0
- Weak duality: If $x \in \mathbb{R}^n$ and $y \in \mathbb{R}^m$ are feasible solutions to the primal and dual problems respectively, then $c^T x \le b^T y$.
- Strong duality: If the primal and dual problems both have feasible solutions, they both have optimal solutions with the same objective function value.
- Complementary slackness: For feasible solutions $x \in \mathbb{R}^n$ and $y \in \mathbb{R}^m$, $x$ and $y$ are optimal if and only if:
- $y_i (b_i - (Ax)_i) = 0$ for all $i = 1,..., m$ (primal complementary slackness).
- $x_j ((A^T y)_j - c_j) = 0$ for all $j = 1,..., n$ (dual complementary slackness).
- Example:
- Primal problem:
max 5x_1 + 6x_2 + 9x_3 + 8x_4
s.t. x_1 + 2x_2 + 3x_3 + x_4 = 5
2y_1 + y_2 >= 6
3y_1 + 2y_2 >= 9
y_1 + 3y_3 >= 8
y_1, y_2 >= 0
- Solution: $x^* = (2, 0, 1, 0)$, $y^* = (3, 2)$
- Verifying complementary slackness: Primal:
- $y_1 (5 - (x_1 + 2x_2 + 3x_3 + x_4)) = 3 \cdot (5 - (2 + 0 + 3 + 0)) = 0$
- $y_2 (3 - (x_1 + x_2 + 2x_3 + 3x_4)) = 2 \cdot (3 - (2 + 0 + 2 + 0)) = 0$ Dual:
- $x_1 ((y_1 + y_2) - 5) = 2 \cdot ((3 + 2) - 5) = 0$
- $x_2 ((2y_1 + y_2) - 6) = 0 \cdot ((6 + 2) - 6) = 0$
- $x_3 ((3y_1 + 2y_2) - 9) = 1 \cdot ((9 + 4) - 9) = 0$
- $x_4 ((y_1 + 3y_2) - 8) = 0 \cdot ((3 + 6) - 8) = 0$
Cardiovascular System
- Blood Vessels
- Arteries: Carry blood away from the heart, thick walls withstand high pressure, elastic fibers allow stretching, smooth muscle controls diameter.
- Veins: Carry blood to the heart, thinner walls, lower pressure, valves prevent backflow and skeletal muscle aids flow.
- Capillaries: Microscopic vessels, thin walls for exchange, connect arteries and veins, nutrient and waste transfer occurs here.
- Blood Flow
- Pulmonary Circuit: to and from lungs: Right ventricle $\rightarrow$ pulmonary artery $\rightarrow$ lungs $\rightarrow$ pulmonary vein $\rightarrow$ left atrium $O_2$ in, $CO_2$ out.
- Systemic Circuit: To and from body: Left ventricle $\rightarrow$ aorta $\rightarrow$ body $\rightarrow$ vena cava $\rightarrow$ right atrium: Nutrient delivery, waste removal.
- Heart Anatomy
- Chambers: Atria (right and left) receive blood, ventricles (right and left) pump blood.
- Valves: Atrioventricular (AV): Between atria and ventricles: Tricuspid (right), Bicuspid/Mitral (left), semilunar: Between ventricles and arteries: Pulmonary, Aortic.
- Vessels: Aorta (from left ventricle, to body), Vena Cava (to right atrium, from body: Superior - upper body, Inferior - lower body), Pulmonary Artery (from right ventricle, to lungs), Pulmonary Vein (to left atrium, from lungs).
- Cardiac Cycle
- Systole: contraction phase: ventricles pump blood
- Diastole: relaxation phase: ventricles fill with blood
- Regulation
- Heart Rate: Autonomic nervous system: Sympathetic (increases rate), Parasympathetic (decreases rate), Hormones (e.g., epinephrine), Exercise, stress, etc.
- Blood Pressure: Force of blood on vessel walls, systolic/diastolic (e.g., 120/80 mmHg), regulated by: heart rate, blood volume, vasoconstriction/vasodilation Diagram notes blood flow direction.
Erwartungswert und Varianz Zufälliger Variablen
- Zufällige Variablen are a tool for modelling experiments.
- Erwartungswert and Varianz help to characterize the distribution.
- Erwartungswert
- Describes the expected value of the variable $E(X)$.
- Discreet: $E(X)=\sum_{x} x \cdot p(x)$
- Fair dice: $E(X)=1 \cdot \frac{1}{6}+2 \cdot \frac{1}{6}+3 \cdot \frac{1}{6}+4 \cdot \frac{1}{6}+5 \cdot \frac{1}{6}+6 \cdot \frac{1}{6}=3.5$
- Continuous: $E(X)=\int_{-\infty}^{\infty} x \cdot f(x) d x$
- Varianz
- Varianz measures how spread out a variable is around its mean
- Defined: $Var(X)=E\left((X-\mu)^{2}\right)$
- Diskrete Varianz: $Var(X)=\sum_{x}(x-\mu)^{2} \cdot p(x)$
- Continuous Varianz: $Var(X)=\int_{-\infty}^{\infty}(x-\mu)^{2} \cdot f(x) d x$
- Alternate form: $Var(X)=E\left(X^{2}\right)-(E(X))^{2}$
- Standard Abweichung: $\sigma=\sqrt{Var(X)}$
- Rechenregeln for Erwartungswert and Varianz
- $E(aX+b)=aE(X)+b$
- $Var(aX+b)=a^{2}Var(X)$
- IF X and Y are independant variables.
- $E(X+Y)=E(X)+E(Y)$
- $Var(X+Y)=Var(X)+Var(Y)$
- Bernoulli-verteilte $E(X)=p$ and $Var(X)=p(1-p)$
- $E(X)=\mu$ und die Varianz $Var(X)=\sigma^{2}$
Logique
- A proposition, or assertion, is a statement that can be either true or false.
- Examples: «Aujourd'hui, il pleut.» or «2 + 2 = 4.» or «$\forall x \in \mathbb{R}, x^2 \geq 0$.»
- Logical Operators: From one or two propositions, a new one using a logical operator is constructed. Some main operators:
- Négation
- Conjonction
- Disjonction
- Implication
- Équivalence.
- Négation: The negating of proposition, noted non $P$ (ou $\neg P$), est vraie si $P$ is fausse est fausse si $P$ este vraie.
- Conjonction: The conjonction of the proposition, notée $P$ et $Q$ (ou $P \wedge Q$), est vraie si $P$ et $Q$ sont vraies, et fausse dans les autres cas.
- Disjonction: The disjonction of the proposition , notée $P$ ou $Q$ (ou $P \vee Q$), est vraie si l'une au moins des deux propositions est vraie, et fausse si les deux propositions sont fausses.
- Implication: “$P$ implique $Q$”. $P$ est called l'hypothèse et $Q$ la conclusion. $P \Rightarrow Q$ est fausse uniquement lorsque $P$ est vraie et $Q$ est fausse
- $P \Rightarrow Q$ est équivalente à «non $P$ ou $Q$».
- The réciproque de $P \Rightarrow Q$ est $Q \Rightarrow P.
- The contraposée de $P \Rightarrow Q$ est «non $Q \Rightarrow$ non $P$».
- $P \Rightarrow Q$ est équivalente à sa contraposée
- ÉquivalenceL “$P$ est équivalente à $Q$” ou “$P$ si et seulement si $Q$” (souvent abrégé en “$P$ ssi $Q$”). $P \Leftrightarrow Q$ est vraie lorsque $P$ et $Q$ ont la même valeur de vérité.
- Quantificateurs :
- Quantificateur: noté $\forall$ means “pour tout”.
- Quantificateur: noté $\exists$ means “il existe”.
- The addition of vectors, with its graphical methods.
Física
Sum of Vectors
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Graphical Method
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Add two vectors by placing them one after the other, preserving their magnitude, direction, and sense.
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The resultant vector joins the origin of the first vector to the end of the last vector.
$$\overrightarrow{R} = \overrightarrow{A} + \overrightarrow{B}$$
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Sum of More Than Two Vectors
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The procedure is similar to that for two vectors.
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Place the vectors one after the other, maintaining their characteristics.
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The resultant vector joins the origin of the first vector to the end of the last vector.
$$\overrightarrow{R} = \overrightarrow{A} + \overrightarrow{B} + \overrightarrow{C}$$
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Analytical Method, showing components of a vector
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Any vector can be expressed as the sum of two perpendicular vectors called components.
$$A_x = A \cdot \cos{\theta}$$ $$A_y = A \cdot \sin{\theta}$$
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Vector Sum by Components
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Decompose vectors into their components and add the components of each axis.
$$\overrightarrow{R} = \overrightarrow{A} + \overrightarrow{B} + \overrightarrow{C} = (A_x + B_x + C_x) \hat{i} + (A_y + B_y + C_y) \hat{j}$$ $$R_x = A_x + B_x + C_x$$ $$R_y = A_y + B_y + C_y$$ $$R = \sqrt{R_x^2 + R_y^2}$$ $$\theta = \arctan{\frac{R_y}{R_x}}$$
Algèbre linéaire et géométrie II
- Spaces vectoriels on $\mathbb{K}$ is set $E$ nom vide muni de deux opération :
- Addition vectorielle : $(u, v) \mapsto u+v$
- Exterme multiplication : $(\lambda, u) \mapsto \lambda \cdot u = \lambda u$
- Associativité: $(u+v)+w = u+(v+w)$
- Commutativité: $u+v=v+u$
- Existence d'un élément neutre pour l'addition: $u+0_E = 0_E + u = u$ element $0_E$ is the same
- Existence d'un inverse additif: $u+(-u) = (-u)+u = 0_E$
- Distributivité: $\lambda(u+v) = \lambda u + \lambda v$
- Distributivité: $(\lambda + \mu)u = \lambda u + \mu u$
- Compatibilité: $(\lambda \mu)u = \lambda (\mu u)$
- Élément neutre pour la multiplication scalaire: $1_{\mathbb{K}}u = u$
- Subset F that $E$ that is itself de $E$ with the operation.
- $F$ est non vide.
- $F$ est stable par addition.
- $F$ est stable par multiplication scalaire.
Corollaire 1.1:
Soit $E$ of subset $F$ is a subspace vectoriel de $E$ and $F$ est un non vide $\forall u \in E, \exists (-u) \in E, u+(-u) = (-u)+u = 0_E$ 2.$\forall \lambda \in \mathbb{K}, \forall u, v \in F$ then $\lambda u + v \in F$.
- In $\mathbb{R}^2$, les droites of the origine $0_E$ et $E$ sont des sous-espaces vectoriels of $E$
- Soit $E$ un espace vectoriel of $A$ de $E$
- Subset vectoriel engendré par and noted Vect.
- Linear combination (n $\mathbb{N}, \lambda i \in \mathbb{K}, u_i \in A$
- Vector sum of subset
- $F+G$, est définie par $F+G = {u+v \mid u \in F, v \in G }$ Vect + Vect = vect Vect + vect * Linear is the set
- The somme is is direct of if $F \cap G = {0_E }$. On note alors $F \oplus G
- Vectors with F+G vectors with $F$ and $G$ are supplemental if Vect(vectors in $F$) = linvect(vector)$G$
- the vecter of and are supplemental if $E = F \oplus G$, written comme a sum
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