Podcast
Questions and Answers
Which of the following is a genetic cause of Parkinsonism?
Which of the following is a genetic cause of Parkinsonism?
- Sporadic or Idiopathic
- Manganese Poisoning
- Iatrogenic physician induced
- Genetic mutation of a-synuclein and parkin genes (correct)
What is the mechanism by which Manganese Poisoning leads to Parkinsonism?
What is the mechanism by which Manganese Poisoning leads to Parkinsonism?
- Blocks DA receptors
- Reduces dopamine activity
- Interferes with enzyme systems, oxidizes DA (correct)
- Depletes brain monoamines from storage sites
Which form of Parkinsonism is caused by infarcts in the region of the putamen?
Which form of Parkinsonism is caused by infarcts in the region of the putamen?
- Arteriosclerotic (correct)
- Von Economo's
- Post encephalitic
- MPTP
Which form of Parkinsonism is associated with slow progressive deterioration and development of Parkinson symptoms?
Which form of Parkinsonism is associated with slow progressive deterioration and development of Parkinson symptoms?
Which compound, when enzymatically reacted with MAOb, forms superoxides breaking down to MPP+ and causes Parkinsonism?
Which compound, when enzymatically reacted with MAOb, forms superoxides breaking down to MPP+ and causes Parkinsonism?
Which drug is a precursor of dopamine and can alleviate Parkinsonism?
Which drug is a precursor of dopamine and can alleviate Parkinsonism?
What is the role of carbidopa in the treatment of Parkinsonism?
What is the role of carbidopa in the treatment of Parkinsonism?
Which drug combination, using generic drug names is commonly used to treat Parkinsonism?
Which drug combination, using generic drug names is commonly used to treat Parkinsonism?
Which enzyme does ENTACAPONE inhibit?
Which enzyme does ENTACAPONE inhibit?
What is the main action of ENTACAPONE?
What is the main action of ENTACAPONE?
Which drug can be hepatotoxic?
Which drug can be hepatotoxic?
Which enzyme does TOLCAPONE inhibit?
Which enzyme does TOLCAPONE inhibit?
What is the main action of AMANTADINE in the treatment of Parkinsonism?
What is the main action of AMANTADINE in the treatment of Parkinsonism?
Which drug is a D2 agonist and has a longer duration of action than l-dopa?
Which drug is a D2 agonist and has a longer duration of action than l-dopa?
Which drug has affinity for D3 receptors and can be used as monotherapy for mild Parkinsonism cases?
Which drug has affinity for D3 receptors and can be used as monotherapy for mild Parkinsonism cases?
Which drug is a D1 and D2 agonist, more potent than bromocriptine, and has a longer duration of action than l-dopa?
Which drug is a D1 and D2 agonist, more potent than bromocriptine, and has a longer duration of action than l-dopa?
Which drug is a D2 agonist and is used for patients with mild symptoms to reduce fluctuations in response to l-dopa treatment?
Which drug is a D2 agonist and is used for patients with mild symptoms to reduce fluctuations in response to l-dopa treatment?
Which of the following is a toxic side effect of l-dopa?
Which of the following is a toxic side effect of l-dopa?
What is the main cause of orthostatic hypotension in l-dopa treatment?
What is the main cause of orthostatic hypotension in l-dopa treatment?
What is the treatment for dyskinesia (chorea) caused by l-dopa overdose?
What is the treatment for dyskinesia (chorea) caused by l-dopa overdose?
What is the cause of mental effects such as agitation and insomnia in l-dopa treatment?
What is the cause of mental effects such as agitation and insomnia in l-dopa treatment?
Which of the following is a long-term complication of Levodopa treatment?
Which of the following is a long-term complication of Levodopa treatment?
Which phenomenon refers to the end-of-dose deterioration in motor performance?
Which phenomenon refers to the end-of-dose deterioration in motor performance?
What is the cause of the 'on-off' phenomenon in Levodopa treatment?
What is the cause of the 'on-off' phenomenon in Levodopa treatment?
Which enzyme breaks down NE and 5-HT in the CNS in the central nervous system?
Which enzyme breaks down NE and 5-HT in the CNS in the central nervous system?
Which drug blocks dopamine receptors and can decrease dopamine activity by depleting stores of central dopamine?
Which drug blocks dopamine receptors and can decrease dopamine activity by depleting stores of central dopamine?
Which vitamin can reduce the effectiveness of l-dopa?
Which vitamin can reduce the effectiveness of l-dopa?
Which drug interferes with the absorption of l-dopa from the gut?
Which drug interferes with the absorption of l-dopa from the gut?
Which drug inhibits decarboxylase activity primarily in the periphery, leading to a longer duration of action than carbidopa?
Which drug inhibits decarboxylase activity primarily in the periphery, leading to a longer duration of action than carbidopa?
Which drug is used as a supplement prior to L-DOPA treatment to increase DA activity by inhibiting MAO-B activity? Generic names only!!
Which drug is used as a supplement prior to L-DOPA treatment to increase DA activity by inhibiting MAO-B activity? Generic names only!!
Which drug is a precursor of dopamine and crosses the Blood Brain Barrier?
Which drug is a precursor of dopamine and crosses the Blood Brain Barrier?
Which drug is an anti-cholinergic drug used to alleviate Parkinsonism symptoms?
Which drug is an anti-cholinergic drug used to alleviate Parkinsonism symptoms?
Which drug is a histamine (H1) blocker and is used to alleviate Parkinsonism symptoms?
Which drug is a histamine (H1) blocker and is used to alleviate Parkinsonism symptoms?
Which drug is a synthetic drug and is used to alleviate Parkinsonism symptoms?
Which drug is a synthetic drug and is used to alleviate Parkinsonism symptoms?
Which class of drugs blocks dopamine receptors?
Which class of drugs blocks dopamine receptors?
Which drugs deplete brain monoamines from storage sites?
Which drugs deplete brain monoamines from storage sites?
Which enzyme breaks down dopamine in the brain?
Which enzyme breaks down dopamine in the brain?
Which class of drugs blocks dopamine receptors?
Which class of drugs blocks dopamine receptors?
Which enzyme breaks down dopamine in the brain?
Which enzyme breaks down dopamine in the brain?
Which of the following is an adverse effect of anticholinergic drugs?
Which of the following is an adverse effect of anticholinergic drugs?
Which of the following is NOT an adverse effect of anticholinergic drugs?
Which of the following is NOT an adverse effect of anticholinergic drugs?
Which drug is a neurotoxin selectively toxic to the substantia nigra cells, causing almost all symptoms of Parkinson's disease?
Which drug is a neurotoxin selectively toxic to the substantia nigra cells, causing almost all symptoms of Parkinson's disease?
Which nutrient has been shown to relieve an average of 70% of Parkinson's disease symptoms?
Which nutrient has been shown to relieve an average of 70% of Parkinson's disease symptoms?
Which therapeutic approach for Parkinson's disease involves the implantation of stem cells genetically engineered to produce dopamine?
Which therapeutic approach for Parkinson's disease involves the implantation of stem cells genetically engineered to produce dopamine?
Which surgical therapy for Parkinson's disease is permanent? It lessens motor functions
Which surgical therapy for Parkinson's disease is permanent? It lessens motor functions
Which surgical therapy for Parkinson's disease has a higher technical difficulty?
Which surgical therapy for Parkinson's disease has a higher technical difficulty?
Which therapeutic approach for Parkinson's disease has shown unsatisfactory initial results?
Which therapeutic approach for Parkinson's disease has shown unsatisfactory initial results?
Which type of agents could protect neurons from cell death and result in a slower progression of Parkinson's disease?
Which type of agents could protect neurons from cell death and result in a slower progression of Parkinson's disease?
Which surgical therapy for Parkinson's disease has a greater effect on reducing tremor but less effect on motor fluctuations?
Which surgical therapy for Parkinson's disease has a greater effect on reducing tremor but less effect on motor fluctuations?
Which nutrient has been shown to relieve between 10-60% of Parkinson's disease symptoms?
Which nutrient has been shown to relieve between 10-60% of Parkinson's disease symptoms?
Flashcards are hidden until you start studying
