Parallel Testing for Monitoring Antibody Increases During Pregnancy
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Questions and Answers

When should a repeat antibody screen be performed in the management of Hemolytic Disease?

  • Only if the patient has a history of unexpected antibodies
  • In the third trimester if the patient was transfused
  • At the initial prenatal visit
  • In parallel with the initial sample at 2- to 4-week intervals (correct)

    • What is the purpose of conducting antibody titration for IgG antibodies in the management of Hemolytic Disease?

  • To confirm the presence of D-antigen antibodies
  • To identify clinically significant antibodies
  • To determine the baseline level of IgG antibodies (correct)
  • To exclude the possibility of other unexpected antibodies

    • What is the significance of performing antibody titration before RhIG therapy in D-negative patients?

  • To prevent adverse reactions during RhIG therapy (correct)
  • To establish a baseline level of IgG antibodies
  • To confirm the presence of D-antigen antibodies
  • To identify if there are clinically significant antibodies present

    • What is the significance of a rising titer of 2 or greater in antibody testing during pregnancy?

    <p>It implies a higher risk for Hemolytic Disease of the Newborn (HDFN)</p> Signup and view all the answers

    What is the main reason for performing antibody screening for other erythrocyte antibodies in pregnant mothers?

    <p>To identify antibodies that may cause Hemolytic Disease of the Newborn (HDFN)</p> Signup and view all the answers

    Why is it essential to keep the baseline antibody frozen for future testing and comparison?

    <p>To ensure accurate antibody titration results</p> Signup and view all the answers

    What care should be provided if a pregnant mother is found to have positive anti-D antibodies?

    <p>Proper care of the current pregnancy should be done</p> Signup and view all the answers

    What type of incompatibility can impact the outcome of Hemolytic Disease of the Newborn?

    <p>Rh incompatibility</p> Signup and view all the answers

    What is the significance of antibody titration in decision making for procedures related to Hemolytic Disease of the Newborn?

    <p>Assists in deciding when to perform amniocentesis</p> Signup and view all the answers

    Why is it important for OB-GYNs to take a detailed maternal history to prevent Hemolytic Disease of the Newborn?

    <p>To identify potential risk factors for sensitization</p> Signup and view all the answers

    In which pregnancy does the text state that Hemolytic Disease of the Newborn will ALWAYS be a principle concern?

    <p>Second pregnancy</p> Signup and view all the answers

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