Podcast
Questions and Answers
What is the diameter of the naked icosahedral capsid of Papillomaviridae?
What is the diameter of the naked icosahedral capsid of Papillomaviridae?
- ~55nm (correct)
- ~100nm
- ~30nm
- ~80nm
How many open reading frames (ORFs) are present in the Papillomavirus genome?
How many open reading frames (ORFs) are present in the Papillomavirus genome?
- 4-6 ORFs
- 2-4 ORFs
- 12-15 ORFs
- 8-10 ORFs (correct)
What is the major cause of cancer in women attributed to some types of human papillomaviruses (HPV)?
What is the major cause of cancer in women attributed to some types of human papillomaviruses (HPV)?
- Uterine cancer
- Breast cancer
- Ovarian cancer
- Cervical carcinoma (correct)
Where are the two polyadenylation signals located for viral mRNA transcription in Papillomavirus?
Where are the two polyadenylation signals located for viral mRNA transcription in Papillomavirus?
Which protein of HPV interacts with cell cycle regulatory proteins, particularly retinoblastoma (Rb) protein?
Which protein of HPV interacts with cell cycle regulatory proteins, particularly retinoblastoma (Rb) protein?
What is the main function of E7 protein in HPV infection?
What is the main function of E7 protein in HPV infection?
What is the result of the integration of HPV genome into cellular genome in cancer cells?
What is the result of the integration of HPV genome into cellular genome in cancer cells?
Which region of the viral DNA contains enhancer sequence(s) and is sometimes called URR (upstream regulatory region)?
Which region of the viral DNA contains enhancer sequence(s) and is sometimes called URR (upstream regulatory region)?
What is the function of E1 protein in HPV infection?
What is the function of E1 protein in HPV infection?
Which proteins are involved in promoting the encapsidation of newly replicated HPV genomes?
Which proteins are involved in promoting the encapsidation of newly replicated HPV genomes?
What is the function of the late promoter in HPV infection?
What is the function of the late promoter in HPV infection?
Which cellular protein does HPV E6 associate with to stimulate ubiquitination and degradation of p53?
Which cellular protein does HPV E6 associate with to stimulate ubiquitination and degradation of p53?
What happens when HPV genome integrates into different sites in cellular genome in cancer cells?
What happens when HPV genome integrates into different sites in cellular genome in cancer cells?
What is the function of HPV L2 protein?
What is the function of HPV L2 protein?
What does inhibition of RB lead to in HPV-infected cells?
What does inhibition of RB lead to in HPV-infected cells?
What is an effective means for reducing cervical cancer deaths according to Section 2.5?
What is an effective means for reducing cervical cancer deaths according to Section 2.5?
What is the main cause of genital tract cancers associated with oncogenic human papillomaviruses?
What is the main cause of genital tract cancers associated with oncogenic human papillomaviruses?
Which type of cancers can be caused by some types of human papillomaviruses in both men and women?
Which type of cancers can be caused by some types of human papillomaviruses in both men and women?
What is the function of E7 protein in HPV infection?
What is the function of E7 protein in HPV infection?
Where are the two polyadenylation signals located for viral mRNA transcription in Papillomavirus?
Where are the two polyadenylation signals located for viral mRNA transcription in Papillomavirus?
Which protein of HPV interacts with cell cycle regulatory proteins, particularly retinoblastoma (Rb) protein?
Which protein of HPV interacts with cell cycle regulatory proteins, particularly retinoblastoma (Rb) protein?
What is the function of the late promoter in HPV infection?
What is the function of the late promoter in HPV infection?
What is the main function of E1 protein in HPV infection?
What is the main function of E1 protein in HPV infection?
What is the result of the integration of HPV genome into cellular genome in cancer cells?
What is the result of the integration of HPV genome into cellular genome in cancer cells?
What is the function of HPV L2 protein?
What is the function of HPV L2 protein?
What does inhibition of RB lead to in HPV-infected cells?
What does inhibition of RB lead to in HPV-infected cells?
What happens when HPV genome integrates into different sites in cellular genome in cancer cells?
What happens when HPV genome integrates into different sites in cellular genome in cancer cells?
What is an effective means for reducing cervical cancer deaths according to Section 2.5?
What is an effective means for reducing cervical cancer deaths according to Section 2.5?
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