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Pain Pathways and Nociceptors

Created by

@DauntlessShark9501

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Questions and Answers

What type of nerve endings in the skin are nociceptors?

Dendritic nerve endings

Free nerve endings (correct)

Encapsulated nerve endings

Myelinated nerve endings

What is the function of ion channels on nociceptor terminals?

To inhibit the release of neurotransmitters

To hyperpolarize the neurons

To stimulate the release of hormones

To depolarize the neurons (correct)

What is the result of nociceptor activation?

Release of neurotransmitters

Stimulation of pleasure pathways

Setting off nociceptive impulses along pain pathways (correct)

Inhibition of pain pathways

What type of substances can block nociceptors?

Local anaesthetics Signup and view all the answers

What is the effect of local anaesthetics on nociceptors?

Blockade of nociceptors Signup and view all the answers

What is the primary function of ion channels on nociceptor terminals?

To act as molecular transducers Signup and view all the answers

What is the effect of depolarization on nociceptor neurons?

It sets off nociceptive impulses along the pain pathways Signup and view all the answers

What is the role of nociceptors in the skin?

To detect damaging stimuli Signup and view all the answers

What is the mechanism by which local anaesthetics interact with nociceptors?

By blocking ion channels Signup and view all the answers

What is the result of blocking ion channels on nociceptor terminals?

Decreased pain transmission Signup and view all the answers

Study Notes

Nociceptors and Pain Pathways

Nociceptors are free nerve endings found in the skin
Various stimuli activate ion channels present on nociceptor terminals, acting as molecular transducers
Activation of these ion channels leads to depolarization of nociceptor neurons, initiating nociceptive impulses
Nociceptive impulses then propagate along pain pathways
Local anaesthetics, such as lidocaine, can block nociceptor activity

Nociceptors and Pain Pathways

Nociceptors are free nerve endings found in the skin
Various stimuli activate ion channels present on nociceptor terminals, acting as molecular transducers
Activation of these ion channels leads to depolarization of nociceptor neurons, initiating nociceptive impulses
Nociceptive impulses then propagate along pain pathways
Local anaesthetics, such as lidocaine, can block nociceptor activity

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Description

Learn about nociceptors, free nerve endings in the skin, and how they activate pain pathways. Understand the role of ion channels and local anaesthetics in pain transmission.