Pain Pathways and Nociceptors
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Questions and Answers

What type of nerve endings in the skin are nociceptors?

  • Dendritic nerve endings
  • Free nerve endings (correct)
  • Encapsulated nerve endings
  • Myelinated nerve endings
  • What is the function of ion channels on nociceptor terminals?

  • To inhibit the release of neurotransmitters
  • To hyperpolarize the neurons
  • To stimulate the release of hormones
  • To depolarize the neurons (correct)
  • What is the result of nociceptor activation?

  • Release of neurotransmitters
  • Stimulation of pleasure pathways
  • Setting off nociceptive impulses along pain pathways (correct)
  • Inhibition of pain pathways
  • What type of substances can block nociceptors?

    <p>Local anaesthetics</p> Signup and view all the answers

    What is the effect of local anaesthetics on nociceptors?

    <p>Blockade of nociceptors</p> Signup and view all the answers

    What is the primary function of ion channels on nociceptor terminals?

    <p>To act as molecular transducers</p> Signup and view all the answers

    What is the effect of depolarization on nociceptor neurons?

    <p>It sets off nociceptive impulses along the pain pathways</p> Signup and view all the answers

    What is the role of nociceptors in the skin?

    <p>To detect damaging stimuli</p> Signup and view all the answers

    What is the mechanism by which local anaesthetics interact with nociceptors?

    <p>By blocking ion channels</p> Signup and view all the answers

    What is the result of blocking ion channels on nociceptor terminals?

    <p>Decreased pain transmission</p> Signup and view all the answers

    Study Notes

    Nociceptors and Pain Pathways

    • Nociceptors are free nerve endings found in the skin
    • Various stimuli activate ion channels present on nociceptor terminals, acting as molecular transducers
    • Activation of these ion channels leads to depolarization of nociceptor neurons, initiating nociceptive impulses
    • Nociceptive impulses then propagate along pain pathways
    • Local anaesthetics, such as lidocaine, can block nociceptor activity

    Nociceptors and Pain Pathways

    • Nociceptors are free nerve endings found in the skin
    • Various stimuli activate ion channels present on nociceptor terminals, acting as molecular transducers
    • Activation of these ion channels leads to depolarization of nociceptor neurons, initiating nociceptive impulses
    • Nociceptive impulses then propagate along pain pathways
    • Local anaesthetics, such as lidocaine, can block nociceptor activity

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    Description

    Learn about nociceptors, free nerve endings in the skin, and how they activate pain pathways. Understand the role of ion channels and local anaesthetics in pain transmission.

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