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Questions and Answers
What type of nerve endings in the skin are nociceptors?
What type of nerve endings in the skin are nociceptors?
- Dendritic nerve endings
- Free nerve endings (correct)
- Encapsulated nerve endings
- Myelinated nerve endings
What is the function of ion channels on nociceptor terminals?
What is the function of ion channels on nociceptor terminals?
- To inhibit the release of neurotransmitters
- To hyperpolarize the neurons
- To stimulate the release of hormones
- To depolarize the neurons (correct)
What is the result of nociceptor activation?
What is the result of nociceptor activation?
- Release of neurotransmitters
- Stimulation of pleasure pathways
- Setting off nociceptive impulses along pain pathways (correct)
- Inhibition of pain pathways
What type of substances can block nociceptors?
What type of substances can block nociceptors?
What is the effect of local anaesthetics on nociceptors?
What is the effect of local anaesthetics on nociceptors?
What is the primary function of ion channels on nociceptor terminals?
What is the primary function of ion channels on nociceptor terminals?
What is the effect of depolarization on nociceptor neurons?
What is the effect of depolarization on nociceptor neurons?
What is the role of nociceptors in the skin?
What is the role of nociceptors in the skin?
What is the mechanism by which local anaesthetics interact with nociceptors?
What is the mechanism by which local anaesthetics interact with nociceptors?
What is the result of blocking ion channels on nociceptor terminals?
What is the result of blocking ion channels on nociceptor terminals?
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Study Notes
Nociceptors and Pain Pathways
- Nociceptors are free nerve endings found in the skin
- Various stimuli activate ion channels present on nociceptor terminals, acting as molecular transducers
- Activation of these ion channels leads to depolarization of nociceptor neurons, initiating nociceptive impulses
- Nociceptive impulses then propagate along pain pathways
- Local anaesthetics, such as lidocaine, can block nociceptor activity
Nociceptors and Pain Pathways
- Nociceptors are free nerve endings found in the skin
- Various stimuli activate ion channels present on nociceptor terminals, acting as molecular transducers
- Activation of these ion channels leads to depolarization of nociceptor neurons, initiating nociceptive impulses
- Nociceptive impulses then propagate along pain pathways
- Local anaesthetics, such as lidocaine, can block nociceptor activity
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