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Questions and Answers
Which molecule is released into the cytoplasm when phospholipase C cleaves phosphatidylinositol 4,5-bisphosphate (PIP2)?
Which molecule is released into the cytoplasm when phospholipase C cleaves phosphatidylinositol 4,5-bisphosphate (PIP2)?
- Inositol 1,4,5-trisphosphate (IP3) (correct)
- Diacylglycerol (DAG)
- Calmodulin
- Calcium
What is the role of IP3 receptors in the contraction of uterine smooth muscle?
What is the role of IP3 receptors in the contraction of uterine smooth muscle?
- They permit the passage of calcium from the sarcoplasmic reticulum (SR) to the cytoplasm (correct)
- They bind to calmodulin
- They phosphorylate myosin light chains
- They activate phospholipase C
What is the role of MLCK in the contraction of uterine smooth muscle?
What is the role of MLCK in the contraction of uterine smooth muscle?
- It phosphorylates myosin light chains (correct)
- It binds to calmodulin
- It permits the passage of calcium from the sarcoplasmic reticulum (SR) to the cytoplasm
- It activates phospholipase C
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