3 Questions
Which molecule is released into the cytoplasm when phospholipase C cleaves phosphatidylinositol 4,5-bisphosphate (PIP2)?
Inositol 1,4,5-trisphosphate (IP3)
What is the role of IP3 receptors in the contraction of uterine smooth muscle?
They permit the passage of calcium from the sarcoplasmic reticulum (SR) to the cytoplasm
What is the role of MLCK in the contraction of uterine smooth muscle?
It phosphorylates myosin light chains
Test your knowledge on the role of oxytocin in uterine contractions during labor and its signaling pathway through Gq G-protein coupled receptor and phospholipase C activation.
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