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Oxygen Sensitivity in Obligate Anaerobes

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Oxygen Sensitivity in Obligate Anaerobes

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Questions and Answers

What factors contribute to the oxygen sensitivity of obligate anaerobes?

oxidative stress and enzyme production

What is the oxygen tolerance range for obligate anaerobes?

0.5% - 8%

What are the damaging compounds to microbes known as?

reactive oxygen species (ROS)

How does molecular oxygen get reduced within cells?

to superoxide (O−2) and hydrogen peroxide (H2O2) Signup and view all the answers

What happens when superoxide and hydrogen peroxide react?

formation of a free hydroxyl radical (OH.) Signup and view all the answers

What are the consequences of normal atmospheric concentrations of oxygen on obligate anaerobes?

Normal atmospheric concentrations of oxygen can kill obligate anaerobes. Signup and view all the answers

What compounds are formed when oxygen is reduced within cells?

Oxygen is reduced to superoxide (O−2) and hydrogen peroxide (H2O2) within cells. Signup and view all the answers

What are some factors that contribute to the oxygen sensitivity of obligate anaerobes?

The oxygen sensitivity of obligate anaerobes can be attributed to oxidative stress and enzyme production. Signup and view all the answers

What are reactive oxygen species (ROS)?

Reactive oxygen species (ROS) are highly reactive compounds that are damaging to microbes. Signup and view all the answers

In what ways can oxygen damage obligate anaerobes that do not involve oxidative stress?

Oxygen can damage obligate anaerobes through ways not involving oxidative stress by forming free hydroxyl radicals (OH.) Signup and view all the answers