Overview of the Endocrine System
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Questions and Answers

What is a key characteristic that differentiates endocrine glands from exocrine glands?

  • Presence of ducts
  • Secretion of hormones directly into the blood (correct)
  • Secretion of mucous or serous fluids
  • Production of enzymes for digestion
  • What anatomical structure connects the two lobes of the thyroid gland?

  • Capsule
  • Carotid sheath
  • Fascia
  • Isthmus (correct)
  • Which nerve runs in the tracheoesophageal groove related to the thyroid gland?

  • Recurrent laryngeal nerve (correct)
  • Phrenic nerve
  • External laryngeal nerve
  • Vagus nerve
  • Which artery is the first branch of the external carotid artery relevant to the thyroid gland?

    <p>Superior thyroid artery</p> Signup and view all the answers

    Which structures are located medially to the thyroid gland?

    <p>Pharynx and larynx</p> Signup and view all the answers

    Which of the following glands is closely associated with the thyroid gland?

    <p>Parathyroid gland</p> Signup and view all the answers

    What is the anatomical position of the thyroid gland?

    <p>Anterior to the larynx and trachea</p> Signup and view all the answers

    What is the clinical significance of the hypothalamo-hypophyseal portal system?

    <p>It allows hormonal communication between the hypothalamus and pituitary gland</p> Signup and view all the answers

    What type of cells primarily make up the cortex of the thymus gland?

    <p>T lymphocytes (thymocytes)</p> Signup and view all the answers

    Which feature is characteristic of the medulla in the thymus gland?

    <p>Keratins in Hassall's corpuscles</p> Signup and view all the answers

    What is the role of the tunica albuginea in the testes?

    <p>Encapsulates the testes</p> Signup and view all the answers

    What hormonal function do the corpus luteum and corpus albicans in the ovaries primarily serve?

    <p>Production of estrogen and progesterone</p> Signup and view all the answers

    What condition is characterized by the accumulation of fluid in the tunica vaginalis of the testes?

    <p>Hydrocoele testis</p> Signup and view all the answers

    What is the primary risk associated with high ligation of the superior thyroid artery during thyroidectomy?

    <p>Injury to the recurrent laryngeal nerve</p> Signup and view all the answers

    Where does the inferior thyroid artery arise from?

    <p>Subclavian artery</p> Signup and view all the answers

    Which type of cells are primarily found in the medulla of the ovaries?

    <p>Loose fibroelastic tissue cells</p> Signup and view all the answers

    What causes the changes in the ovaries that lead to menopause?

    <p>Shrinking and scar formation in the ovaries</p> Signup and view all the answers

    What is the typical anatomical arrangement of the inferior thyroid artery in relation to the recurrent laryngeal nerve?

    <p>The ITA crosses over the recurrent laryngeal nerve</p> Signup and view all the answers

    Which of the following statements about the thyroid 'ima' artery is true?

    <p>It supplies the isthmus of the thyroid gland</p> Signup and view all the answers

    What is one of the defining features of Leydig cells in the testes?

    <p>Surround seminiferous tubules</p> Signup and view all the answers

    During thyroid surgery, what should be done to avoid injury to the recurrent laryngeal nerve when ligating the inferior thyroid artery?

    <p>Ligation should be performed away from the gland</p> Signup and view all the answers

    What type of epithelium lines the thyroid follicles during their active stage?

    <p>Columnar epithelium</p> Signup and view all the answers

    Which vein drains the upper pole of the thyroid gland?

    <p>Superior thyroid vein</p> Signup and view all the answers

    What can cause hoarseness and vocal cord paralysis after thyroid surgery?

    <p>Injury to the recurrent laryngeal nerve</p> Signup and view all the answers

    What type of hormones does the anterior pituitary produce?

    <p>Peptide hormones</p> Signup and view all the answers

    Which type of cell in the anterior pituitary is responsible for producing growth hormone?

    <p>Alpha acidophils</p> Signup and view all the answers

    What is the function of antidiuretic hormone (vasopressin) produced by the posterior pituitary?

    <p>Constricts arterioles to raise blood pressure</p> Signup and view all the answers

    What condition results from excessive production of adrenocorticotropic hormone (ACTH)?

    <p>Cushing's disease</p> Signup and view all the answers

    What structural feature distinguishes chromophil cells from chromophobes in the anterior pituitary?

    <p>Distinct cell membranes and granular cytoplasm</p> Signup and view all the answers

    Hypopituitarism can be caused by which of the following conditions?

    <p>Necrosis of cells due to blockage of arterial supply</p> Signup and view all the answers

    Which part of the pituitary gland is associated with specialized neuroglial cells called pituicytes?

    <p>Pars nervosa</p> Signup and view all the answers

    What type of blood vessels connect the sinusoidal capillaries in the median eminence to the anterior lobe of the pituitary gland?

    <p>Long portal blood vessels</p> Signup and view all the answers

    Which hormone is produced by the pars intermedia of the pituitary gland?

    <p>Melanocyte-stimulating hormone</p> Signup and view all the answers

    Which of the following correctly describes the anatomy of the adrenal (suprarenal) glands?

    <p>They are yellowish and retroperitoneal.</p> Signup and view all the answers

    What is the main function of the adrenal medulla?

    <p>Secretion of catecholamines</p> Signup and view all the answers

    Which condition is associated with hypoadrenalism?

    <p>Addison's disease</p> Signup and view all the answers

    Which hormone does the pineal gland primarily synthesize?

    <p>Melatonin</p> Signup and view all the answers

    What characterizes the chromaffin cells in the adrenal medulla?

    <p>Granular, faintly basophilic cytoplasm</p> Signup and view all the answers

    Which syndrome is caused by excessive production of aldosterone?

    <p>Conn's syndrome</p> Signup and view all the answers

    What is a distinguishing feature of the pineal gland's histology?

    <p>Clusters of pinealocytes surrounded by capillaries</p> Signup and view all the answers

    Which arteries supply blood to the adrenal gland?

    <p>Superior, middle, and inferior arteries</p> Signup and view all the answers

    What happens to the pineal gland with aging?

    <p>Formation of basophilic extracellular bodies</p> Signup and view all the answers

    Study Notes

    Overview of the Endocrine System

    • Endocrine glands release hormones directly into the bloodstream, whereas exocrine glands utilize ducts for secretion.
    • Major endocrine glands include the thyroid, parathyroid, pituitary, adrenal, pineal, pancreas, thymus, testes, and ovaries.

    Thyroid Gland

    • Located in the anterior neck, spanning C5 to T1 vertebrae; consists of two lobes connected by an isthmus.
    • Surfaces: lateral, medial, and posterior; has upper and lower poles.
    • Covered by pretracheal fascia (outer capsule) and true capsules (inner).
    • Relates to infra-hyoid and sterno-mastoid muscles, recurrent laryngeal nerve, carotid sheath, and prevertebral muscles.

    Thyroid Vasculature

    • Supplied by the superior thyroid artery (branch of the external carotid) and inferior thyroid artery (from the thyrocervical trunk).
    • Venous drainage through superior, middle, and inferior thyroid veins to the internal jugular and brachiocephalic veins.

    Histology of Thyroid Gland

    • Follicles are lined by cuboidal epithelium with eosinophilic colloid in the lumen.
    • Active thyroid shows columnar lining cells, while inactive displays flat to cuboidal cells.

    Pituitary Gland

    • Divided into anterior (pars distalis) and posterior (pars nervosa) lobes with distinct cellular structures.
    • Anterior pituitary produces growth hormone, follicular stimulating hormone, luteinizing hormone, and others; acts on growth, reproductive functions, and the thyroid.
    • The posterior pituitary secretes antidiuretic hormone and oxytocin, affecting water retention and uterine contraction.

    Disorders of Pituitary Gland

    • Adenomas can lead to Cushing’s disease (ACTH excess) or gigantism/acromegaly (GH excess).
    • Panhypopituitarism involves the failure of hormone production, often due to arterial supply blockage.

    Suprarenal (Adrenal) Glands

    • Paired, yellowish glands located atop the kidneys, involved in hormone secretion.
    • Divided into cortex (steroid hormones) and medulla (catecholamines).
    • Blood supply includes superior, middle, and inferior adrenal arteries.

    Histology of Thymus

    • Composed of a loose collagenous capsule with cortical and medullary regions.
    • Cortex contains T lymphocytes and nurse cells, while medulla has eosinophilic epithelial cells and Hassall corpuscles.

    Testes

    • Located in the scrotum, encapsulated by tunica albuginea, and contain seminiferous tubules where sperm is produced.
    • Leydig cells in between tubules produce testosterone.

    Ovaries

    • Found in the pelvic cavity, also encapsulated by a fibrous capsule.
    • Cortex includes developing follicles and corpus structures, while the medulla is composed of loose connective tissue.

    Pineal Gland

    • Small spherical gland in the brain that synthesizes melatonin, regulated by light conditions.
    • Contains pinealocytes (modified neurons) surrounded by fenestrated capillaries; generates calcium and magnesium phosphate matrix, known as pineal sand.

    Pancreas

    • Functions as both an exocrine and endocrine gland, involved in digestive enzyme production and hormone regulation (insulin and glucagon).

    Clinical Significance

    • Conditions such as goitre (thyroid enlargement), pituitary disorders (adenomas), adrenal insufficiency (Addison’s disease), and ovarian cysts can affect endocrine function significantly.

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    Description

    Explore the key components and functions of the endocrine system, focusing specifically on the thyroid gland. Learn about its anatomical features, vasculature, and histological structure. This quiz presents essential information relevant to the study of human biology and physiology.

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