Overview of Cancer and Its Causes
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Questions and Answers

Cancer is the second-leading cause of death in the ______.

world

Some general signs of cancer include fatigue and unexplained ______.

weight changes

Errors in the instructions within ______ can lead to cancer.

DNA

A persistent cough or difficulty ______ can be symptoms of cancer.

<p>breathing</p> Signup and view all the answers

Cancer cells lose the controls that tell them when to stop ______.

<p>growing</p> Signup and view all the answers

If you are worried about your risk of cancer, you should discuss your concerns with your ______.

<p>doctor</p> Signup and view all the answers

Skin changes such as yellowing or sores that won't ______ can indicate cancer.

<p>heal</p> Signup and view all the answers

Gene mutations can instruct cells to allow rapid ______.

<p>growth</p> Signup and view all the answers

Cancer survivors have a risk of cancer __________.

<p>recurrence</p> Signup and view all the answers

Smoking is linked to several types of cancer — not just __________ cancer.

<p>lung</p> Signup and view all the answers

Harmful ultraviolet (UV) rays from the sun can increase your risk of __________ cancer.

<p>skin</p> Signup and view all the answers

Choose a diet rich in fruits and __________.

<p>vegetables</p> Signup and view all the answers

Aim for at least 30 minutes of __________ most days of the week.

<p>exercise</p> Signup and view all the answers

Being __________ or obese may increase your risk of cancer.

<p>overweight</p> Signup and view all the answers

Immunizations may help prevent viruses including hepatitis B, which increases the risk of __________ cancer.

<p>liver</p> Signup and view all the answers

Talk to your doctor about what types of cancer __________ exams are best for you.

<p>screening</p> Signup and view all the answers

A mutation in a tumor suppressor gene allows cancer cells to continue growing and ______.

<p>accumulating</p> Signup and view all the answers

DNA repair genes look for errors in a cell's DNA and make ______.

<p>corrections</p> Signup and view all the answers

The gene mutations you're born with and those that you acquire throughout your life work ______ to cause cancer.

<p>together</p> Signup and view all the answers

Gene mutations can occur for several reasons, including those you are born ______.

<p>with</p> Signup and view all the answers

Certain lifestyle choices, such as smoking and being ______, are known to increase your risk of cancer.

<p>obese</p> Signup and view all the answers

Cancer can take decades to develop; that's why most people diagnosed with cancer are ______ or older.

<p>65</p> Signup and view all the answers

While only a small portion of cancers are due to an inherited ______, family history can play a role.

<p>condition</p> Signup and view all the answers

The environment around you may contain harmful chemicals that can increase your risk of ______.

<p>cancer</p> Signup and view all the answers

Certain cancers and cancer treatments can cause ______, which can often be managed with medications.

<p>nausea</p> Signup and view all the answers

Pain can be caused by cancer or by cancer ______, though not all cancer is painful.

<p>treatment</p> Signup and view all the answers

A mutation in a DNA repair gene may mean that other errors aren't ______, leading cells to become cancerous.

<p>corrected</p> Signup and view all the answers

Obesity, hormones, and chronic inflammation are examples of factors that can cause gene mutations after ______.

<p>birth</p> Signup and view all the answers

Cancer and its treatment can sometimes lead to ______ system problems, including pain and loss of function.

<p>nervous</p> Signup and view all the answers

Fatigue associated with chemotherapy or radiation therapy is ______, but it's usually temporary.

<p>common</p> Signup and view all the answers

Unusual immune system reactions to cancer can lead to symptoms called ______ syndromes.

<p>paraneoplastic</p> Signup and view all the answers

Cancer that advances may ______ to other parts of the body, depending on the type.

<p>spread</p> Signup and view all the answers

Flashcards

Cancer Definition

Uncontrolled cell growth and division that can invade and destroy healthy tissue.

Cancer Spread

Cancer cells can move throughout the body.

Gene Mutation

Changes to DNA instructions that can cause cells to grow abnormally.

Rapid Cell Growth

Gene mutations can tell cells to grow and divide faster than normal.

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Uncontrolled Cell Growth

A cell loses the ability to stop growing, a crucial aspect of cancer development.

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Tumor Suppressor Genes

Genes that normally regulate cell growth.

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Cancer Symptoms

Changes in the body indicating the presence of cancer. However, each cancer type can produce different symptoms.

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Seek Medical Advice

When persistent unusual symptoms arise, visit a doctor immediately.

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Cancer Recurrence Risk

The possibility of cancer returning after treatment.

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Follow-up Care Plan

A plan created by a doctor to monitor for cancer recurrence after treatment.

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Reduce Cancer Risk

Actions taken to lessen the chance of getting cancer.

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Smoking Cessation

Quitting smoking to reduce cancer risk.

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Sun Exposure Limit

Reducing sun exposure to decrease skin cancer risk.

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Healthy Diet

Eating fruits, vegetables, whole grains, and lean protein to reduce cancer risk.

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Regular Exercise

Exercising most days of the week to reduce cancer risk.

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Maintain Healthy Weight

Keeping a healthy weight to lessen cancer risk.

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DNA Repair Gene

A gene that helps fix mistakes in a cell's DNA.

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Inherited Gene Mutation

A gene mutation you receive from your parents.

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Acquired Gene Mutation

A gene mutation that develops after birth.

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Cancer-Causing Substance

A substance that increases the risk of cancer (e.g., carcinogens).

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Cancer Risk Factors

Factors associated with a higher chance of getting cancer.

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Age and cancer

Most cancers are diagnosed in older adults, many taking decades to develop.

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Lifestyle choices and cancer

Certain habits can increase cancer risk, e.g. Smoking, obesity or excessive sun exposure.

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Cancer and genetics

A small percentage of cancers are caused by inherited genetic mutations.

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Cancer and chronic health conditions

Some chronic diseases like ulcerative colitis increase the chance of developing particular cancers.

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Cancer and environment

External factors like workplace and home chemicals can also increase the risk of cancer.

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Cancer and multiple mutations

Combination of inherited and acquired mutations drive cancer development.

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Inherited Mutation

A harmful gene mutation you inherit.

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Cancer Metastasis

Spread of cancer to other parts of the body.

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Study Notes

Cancer Overview

  • Cancer is a group of diseases marked by uncontrolled cell growth, spreading to other body parts.
  • It's the second leading cause of death globally, though survival rates are improving due to better screenings, treatments, and prevention.

Cancer Symptoms

  • Cancer symptoms vary based on affected body part.
  • Common, non-specific symptoms include fatigue, lumps, weight changes, skin changes (color or sores), bowel/bladder issues, persistent cough/trouble breathing, difficulty swallowing, hoarseness, indigestion, muscle/joint pain, fever/night sweats, unexplained bleeding/bruising.
  • Seek medical attention for persistent concerning symptoms.
  • Discuss cancer risk factors with a doctor even without symptoms; get appropriate screenings.

Cancer Causes

  • Cancer arises from DNA mutations within cells.
  • Genes hold instructions for cell functions and growth/division.
  • Mutations can cause cells to malfunction, leading to cancer.

Types of Mutations

  • Mutations cause rapid cell growth.
  • Mutations disable tumor suppressor genes, which normally control cell growth.
  • Mutations interfere with DNA repair mechanisms.

Causes of Gene Mutations

  • Inherited mutations (from parents; rare).
  • Mutations acquired after birth (common) due to factors like smoking, radiation, viruses, chemicals (carcinogens), obesity, hormones, inflammation, and lack of exercise.
  • Normal cell growth sometimes involves errors; sometimes, errors are not repaired, leading to cancer.

Gene Mutation Interactions

  • Inherited and acquired mutations combine to cause cancer.
  • Pre-disposition to cancer (inherited mutations) doesn't guarantee cancer, but increases the risk (may need other mutations).
  • Accumulated mutations are required for cancer formation but the exact number varies.

Risk Factors

  • Age: Most cancer diagnoses are in people aged 65 or older, but it can affect people of any age.
  • Habits: Smoking, excessive alcohol (males >2 drinks/day, females >1 drink/day), excessive sun exposure, obesity, and unsafe sex increase cancer risk.
  • Family history: Inherited conditions are contributors to some cancers; genetic testing can help identify inherited risks.
  • Health conditions: Some chronic health conditions (e.g., ulcerative colitis) increase cancer risks.
  • Environment: Exposure to harmful chemicals (e.g., asbestos, benzene) or second-hand smoke also increases cancer risks.

Cancer Complications

  • Pain (cancer or treatment related).
  • Fatigue (from cancer or treatment).
  • Breathing difficulties.
  • Nausea.
  • Diarrhea/Constipation.
  • Weight loss (often from cancer itself).
  • Chemical imbalances (excessive thirst, urination, constipation, confusion).
  • Nervous system problems (cancer pressing on nerves).
  • Brain cancer (headaches, stroke-like symptoms).
  • Unusual immune system reactions (paraneoplastic syndromes).
  • Metastasis (cancer spread to other parts of the body).
  • Recurrence (cancer return).

Cancer Prevention

  • Quit smoking.
  • Limit sun exposure (shade, protective clothing, sunscreen).
  • Eat a healthy diet (fruits, vegetables, whole grains, lean proteins).
  • Exercise regularly (aim for 30 minutes most days).
  • Maintain a healthy weight.
  • Drink alcohol moderately.
  • Get cancer screenings (as appropriate).
  • Get immunizations for viruses increasing cancer risks (e.g., hepatitis B, HPV).

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Description

This quiz covers essential aspects of cancer, including its definition, symptoms, causes, and types of mutations. Understand how uncontrolled cell growth leads to cancer and recognize common signs that warrant medical attention. Explore the importance of genetic mutations in the development of this disease.

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