Osteoarthritis (OA) Arthritis: Symptoms and Risk Factors
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Questions and Answers

Which factor contributes to an increased risk of knee OA?

  • High manual dexterity
  • Genetic predisposition
  • Prolonged standing (correct)
  • Abnormal hip shape
  • What accounts for 60% of hand and hip OA and 40% of knee OA?

  • Previous injury
  • Genetic factors (correct)
  • Abnormal hip shape
  • Weight
  • What is a common risk factor for developing knee OA?

  • Prolonged standing
  • Age
  • Occupations requiring high manual dexterity
  • High BMI (correct)
  • Which occupation is associated with a higher prevalence of knee OA?

    <p>Occupations requiring kneeling</p> Signup and view all the answers

    What increases the risk of hip OA?

    <p>Abnormal hip shape</p> Signup and view all the answers

    Which factor accounts for 40% of knee OA?

    <p>Genetic factors</p> Signup and view all the answers

    Which joint is commonly affected by osteoarthritis?

    <p>Knee</p> Signup and view all the answers

    What type of cartilage is present in a synovial joint?

    <p>Hyaline cartilage</p> Signup and view all the answers

    What is the role of synovial fluid in a synovial joint?

    <p>Removes waste products</p> Signup and view all the answers

    What happens to the joint space in osteoarthritis?

    <p>Reduces due to cartilage loss</p> Signup and view all the answers

    What is the characteristic feature of osteoarthritis pain at rest?

    <p>Severe and continuous</p> Signup and view all the answers

    What happens to the cartilage layer in osteoarthritis?

    <p>Thins, making underlying bone less protected</p> Signup and view all the answers

    What is the appearance of damaged cartilage in osteoarthritis?

    <p>Brownish-grey</p> Signup and view all the answers

    What are the common signs of osteoarthritis?

    <p>Joint swelling and warmth</p> Signup and view all the answers

    What is a characteristic feature of OA that distinguishes it from other conditions?

    <p>Pain relieved by movement.</p> Signup and view all the answers

    What role does the synovial membrane play in a synovial joint?

    <p>Secretes synovial fluid and lubricates the joint.</p> Signup and view all the answers

    Which type of pain sensation is typically associated with minimal tissue damage?

    <p>Burning and pricking</p> Signup and view all the answers

    What do small diameter afferent nerve fibers underlie?

    <p>Fast and low pain</p> Signup and view all the answers

    What does a person's response to pain reflect?

    <p>Strength and severity of nociceptor activation</p> Signup and view all the answers

    What is the role of nociceptors in pain perception?

    <p>They signal the strength and location of actual or potential tissue-damaging stimuli</p> Signup and view all the answers

    What aspect of pain does the variable quality of pain sensations represent?

    <p>The response to pain</p> Signup and view all the answers

    What is the characteristic feature of prolonged pain sensations?

    <p>Accompanies greater degree of tissue damage</p> Signup and view all the answers

    Which chemical mediator can sensitize the response of nociceptors to normal stimuli?

    <p>Substance P</p> Signup and view all the answers

    Where do nociceptive afferents make synaptic connections with second-order neurons that transmit information to higher centres?

    <p>Dorsal horn</p> Signup and view all the answers

    What type of reflex involves several muscle groups and operates over several spinal levels?

    <p>Polysynaptic reflex</p> Signup and view all the answers

    What is the role of Substantia gelatinosa (SG) cells in pain modulation?

    <p>Presynaptic inhibition of nociceptive afferent terminals</p> Signup and view all the answers

    What is transmitted to spinal cord via nociceptive afferent nerves and influences reflex activity?

    <p>Pain information</p> Signup and view all the answers

    Which chemical mediator can activate nociceptive nerve terminals directly?

    <p>Bradykinin</p> Signup and view all the answers

    Where do polysynaptic reflexes involving nociceptive afferents operate?

    <p>Several spinal levels</p> Signup and view all the answers

    Which pathway do second-order neurons (transmission [T] cells) use to transmit pain information to higher centres?

    <p>Lateral spinothalamic pathway</p> Signup and view all the answers

    What is the role of chemical mediators in initiating the inflammatory response?

    <p>Initiating inflammatory response</p> Signup and view all the answers

    What coordinates the autonomic, psychological, and emotional response to pain?

    <p>Spinoreticular tract</p> Signup and view all the answers

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