Osteoarthritis (OA) Arthritis: Symptoms and Risk Factors
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Questions and Answers

Which factor contributes to an increased risk of knee OA?

  • High manual dexterity
  • Genetic predisposition
  • Prolonged standing (correct)
  • Abnormal hip shape

What accounts for 60% of hand and hip OA and 40% of knee OA?

  • Previous injury
  • Genetic factors (correct)
  • Abnormal hip shape
  • Weight

What is a common risk factor for developing knee OA?

  • Prolonged standing
  • Age
  • Occupations requiring high manual dexterity
  • High BMI (correct)

Which occupation is associated with a higher prevalence of knee OA?

<p>Occupations requiring kneeling (A)</p> Signup and view all the answers

What increases the risk of hip OA?

<p>Abnormal hip shape (B)</p> Signup and view all the answers

Which factor accounts for 40% of knee OA?

<p>Genetic factors (C)</p> Signup and view all the answers

Which joint is commonly affected by osteoarthritis?

<p>Knee (B)</p> Signup and view all the answers

What type of cartilage is present in a synovial joint?

<p>Hyaline cartilage (C)</p> Signup and view all the answers

What is the role of synovial fluid in a synovial joint?

<p>Removes waste products (B)</p> Signup and view all the answers

What happens to the joint space in osteoarthritis?

<p>Reduces due to cartilage loss (C)</p> Signup and view all the answers

What is the characteristic feature of osteoarthritis pain at rest?

<p>Severe and continuous (D)</p> Signup and view all the answers

What happens to the cartilage layer in osteoarthritis?

<p>Thins, making underlying bone less protected (C)</p> Signup and view all the answers

What is the appearance of damaged cartilage in osteoarthritis?

<p>Brownish-grey (C)</p> Signup and view all the answers

What are the common signs of osteoarthritis?

<p>Joint swelling and warmth (C)</p> Signup and view all the answers

What is a characteristic feature of OA that distinguishes it from other conditions?

<p>Pain relieved by movement. (C)</p> Signup and view all the answers

What role does the synovial membrane play in a synovial joint?

<p>Secretes synovial fluid and lubricates the joint. (A)</p> Signup and view all the answers

Which type of pain sensation is typically associated with minimal tissue damage?

<p>Burning and pricking (D)</p> Signup and view all the answers

What do small diameter afferent nerve fibers underlie?

<p>Fast and low pain (A)</p> Signup and view all the answers

What does a person's response to pain reflect?

<p>Strength and severity of nociceptor activation (C)</p> Signup and view all the answers

What is the role of nociceptors in pain perception?

<p>They signal the strength and location of actual or potential tissue-damaging stimuli (C)</p> Signup and view all the answers

What aspect of pain does the variable quality of pain sensations represent?

<p>The response to pain (A)</p> Signup and view all the answers

What is the characteristic feature of prolonged pain sensations?

<p>Accompanies greater degree of tissue damage (B)</p> Signup and view all the answers

Which chemical mediator can sensitize the response of nociceptors to normal stimuli?

<p>Substance P (C)</p> Signup and view all the answers

Where do nociceptive afferents make synaptic connections with second-order neurons that transmit information to higher centres?

<p>Dorsal horn (D)</p> Signup and view all the answers

What type of reflex involves several muscle groups and operates over several spinal levels?

<p>Polysynaptic reflex (B)</p> Signup and view all the answers

What is the role of Substantia gelatinosa (SG) cells in pain modulation?

<p>Presynaptic inhibition of nociceptive afferent terminals (A)</p> Signup and view all the answers

What is transmitted to spinal cord via nociceptive afferent nerves and influences reflex activity?

<p>Pain information (B)</p> Signup and view all the answers

Which chemical mediator can activate nociceptive nerve terminals directly?

<p>Bradykinin (D)</p> Signup and view all the answers

Where do polysynaptic reflexes involving nociceptive afferents operate?

<p>Several spinal levels (A)</p> Signup and view all the answers

Which pathway do second-order neurons (transmission [T] cells) use to transmit pain information to higher centres?

<p>Lateral spinothalamic pathway (D)</p> Signup and view all the answers

What is the role of chemical mediators in initiating the inflammatory response?

<p>Initiating inflammatory response (C)</p> Signup and view all the answers

What coordinates the autonomic, psychological, and emotional response to pain?

<p>Spinoreticular tract (B)</p> Signup and view all the answers

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