Osmolality and Homeostasis Quiz
37 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the normal range of osmolality in mOsm/Kg?

  • 275 - 295 mOsm/Kg (correct)
  • 320 - 340 mOsm/Kg
  • 300 - 325 mOsm/Kg
  • 250 - 270 mOsm/Kg
  • Which fluid compartment accounts for 2/3 of total body fluid?

  • Interstitial Fluid
  • Intracellular Fluid (ICF) (correct)
  • Plasma Fluid
  • Extracellular Fluid (ECF)
  • What type of fluid contains more particles than water?

  • Hypo-osmolar fluid
  • Iso-osmolar fluid
  • Isotonic fluid
  • Hyper-osmolar fluid (correct)
  • Which ion is the primary determinant of the osmolality of intracellular fluid (ICF)?

    <p>Potassium</p> Signup and view all the answers

    Which of the following best describes active transport?

    <p>Use of metabolic energy to transport substances</p> Signup and view all the answers

    What percentage of an average healthy adult's weight is water?

    <p>60%</p> Signup and view all the answers

    Electrolytes are primarily responsible for which of the following functions in the body?

    <p>Conducting electricity in body fluids</p> Signup and view all the answers

    What type of fluid has fewer particles than water?

    <p>Hypo-osmolar fluid</p> Signup and view all the answers

    What primarily influences biotransformation in a person?

    <p>Age and liver health</p> Signup and view all the answers

    What is the main route through which drugs are excreted from the body?

    <p>Kidney</p> Signup and view all the answers

    Which transport method does not require energy for drug movement?

    <p>Facilitated diffusion</p> Signup and view all the answers

    What impacts the bioavailability of orally administered drugs the most?

    <p>First-pass metabolism</p> Signup and view all the answers

    What is the half-life of a drug?

    <p>Time required for 50% of the drug to be eliminated</p> Signup and view all the answers

    What is the primary function of hepatic microsomal enzymes?

    <p>To inactivate drugs and accelerate excretion</p> Signup and view all the answers

    What is a factor that affects drug excretion?

    <p>Blood flow to the organs</p> Signup and view all the answers

    Which property of a drug affects its ability to pass through plasma membranes?

    <p>Lipid solubility</p> Signup and view all the answers

    What does pharmacokinetics primarily study?

    <p>Drug movement throughout the body</p> Signup and view all the answers

    Which of the following is NOT a category of pharmacokinetics?

    <p>Transport</p> Signup and view all the answers

    What is the primary site of drug metabolism in the body?

    <p>Liver</p> Signup and view all the answers

    What does absorption in pharmacokinetics refer to?

    <p>The movement of a substance from administration site to circulation</p> Signup and view all the answers

    Which factor affects the metabolism of a drug?

    <p>Age of the patient</p> Signup and view all the answers

    What is the main focus of pharmacotherapy for hypertension?

    <p>Reducing plasma volume through diuretics</p> Signup and view all the answers

    What role does drug ionization play in pharmacokinetics?

    <p>It influences drug absorption and distribution.</p> Signup and view all the answers

    Which property of a drug is critical for its distribution in the body?

    <p>Lipid solubility</p> Signup and view all the answers

    What is the purpose of a loading dose in drug therapy?

    <p>To allow the drug to reach critical concentration sooner</p> Signup and view all the answers

    Which of the following best describes adverse reactions to drug therapy?

    <p>Unintentional, unexpected reactions at normal dosages</p> Signup and view all the answers

    What occurs during the preclinical investigation phase of the drug approval process?

    <p>Laboratory and animal testing of the drug</p> Signup and view all the answers

    What is drug toxicity?

    <p>When drug levels exceed safe limits in the body</p> Signup and view all the answers

    What does the Department of Health and Human Services oversee?

    <p>The safety, efficacy, and security of drugs and medical devices</p> Signup and view all the answers

    What does a standing order involve?

    <p>It is established in advance for specific situations.</p> Signup and view all the answers

    Which is NOT a system of measurement used in pharmacology?

    <p>Imperial System</p> Signup and view all the answers

    What is the main responsibility of a nurse regarding medication administration?

    <p>To understand the drug order and verify its accuracy.</p> Signup and view all the answers

    Which route of administration involves using a cream or ointment?

    <p>Topical</p> Signup and view all the answers

    Before administering medication, what should be verified?

    <p>The medication order and allergy history.</p> Signup and view all the answers

    What does 'prn' stand for in medication orders?

    <p>As needed based on the patient's condition.</p> Signup and view all the answers

    Which of the following is a guideline before drug administration?

    <p>Wash hands and apply gloves if indicated.</p> Signup and view all the answers

    What is defined as a medication error?

    <p>A preventable event that may lead to inappropriate use or harm.</p> Signup and view all the answers

    Study Notes

    Osmolality and Homeostasis

    • Osmolality measures fluid concentration in the body, mainly influenced by sodium, urea (BUN), and glucose.
    • Average healthy adult: 60% body weight is water; varies with age, sex, and body fat.
    • Homeostasis maintains a balance of fluids, electrolytes, acids, and bases despite environmental changes.
    • Electrolytes are charged ions conducting electricity in all body fluids.

    Body Fluid Distribution

    • Body fluid compartments:
      • Intracellular Fluid (ICF): 2/3 of total body fluid, located within cells.
      • Extracellular Fluid (ECF): accounts for 1/3 of total body fluid, found outside cells (subdivided into interstitial and vascular fluid).
    • Fluid concentration types:
      • Iso-osmolar: equal particle concentration as water.
      • Hypo-osmolar: fewer particles than water.
      • Hyper-osmolar: more particles than water.

    Pharmacokinetics Overview

    • Pharmacokinetics studies drug movement and effects within the body, emphasizing therapeutic applications.
    • Key processes include Absorption, Distribution, Metabolism, and Excretion (ADME).
    • Drug absorption involves moving substances across membranes to circulating fluids.

    Drug Absorption and Metabolism

    • Absorption routes include skin, mucous membranes, GI tract, and respiratory system.
    • Metabolism (biotransformation) converts drugs into forms easier for elimination, primarily occurring in the liver.
    • Factors affecting metabolism include age, liver health, drug formulation, size, and solubility.

    Drug Excretion

    • Excretion removes drugs from the body, mainly via the kidneys, with other routes including the lungs and skin.
    • Drug half-life indicates the time required for 50% elimination from the body.
    • Drug excretion influenced by liver/kidney function, blood flow, ionization, and lipid solubility.

    Drug Administration Principles

    • Medication knowledge: Understand drug orders, patient compliance, and schedules.
    • Adhere to the 10 Rights of Drug Administration to ensure proper dosing and delivery.
    • Routes include enteral (oral), topical (creams/ointments), and parenteral (IV/IM).

    Drug Approval Process

    • Four phases: Preclinical Investigation, Clinical Investigation, Review of New Drug Application (NDA), and approval process by health authorities.
    • Monitoring for side effects, adverse reactions, and drug toxicity is crucial during therapy.

    Medication Errors and Guidelines

    • Medication errors are preventable events leading to inappropriate use.
    • Guidelines before administration include verifying orders, checking for allergies, and documenting patient concerns.
    • Proper hand hygiene and glove use is essential in safe medication practices.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Related Documents

    Description

    Test your knowledge on the concepts of osmolality and how it contributes to the maintenance of homeostasis in the human body. Explore key topics such as active transport and the balance of fluids and electrolytes within our biological systems.

    More Like This

    Renal System Functions Quiz
    15 questions
    Osmolality and Body Fluid Volume Quiz
    36 questions

    Osmolality and Body Fluid Volume Quiz

    PicturesqueOphicleide2079 avatar
    PicturesqueOphicleide2079
    Understanding Osmolality
    38 questions

    Understanding Osmolality

    AlluringDalmatianJasper avatar
    AlluringDalmatianJasper
    Human Physiology: Osmolality and Regulation
    18 questions
    Use Quizgecko on...
    Browser
    Browser