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Questions and Answers
What is the main focus of the study mentioned in the text?
What is the main focus of the study mentioned in the text?
- Investigation of chemotherapy resistance mutations in NSCLC
- Comparison of Osimertinib with and without Chemotherapy in EGFR-mutated NSCLC (correct)
- Assessment of chemotherapy as a first-line treatment for NSCLC
- Evaluation of third-generation EGFR-TKI inhibitors in NSCLC treatment
What type of trial design was used in the study?
What type of trial design was used in the study?
- Phase 1, single-center, double-blind trial
- Phase 3, international, open-label trial (correct)
- Observational cohort study
- Phase 2, multicenter, randomized controlled trial
What is the primary target of Osimertinib?
What is the primary target of Osimertinib?
- ALK gene mutations
- KRAS gene mutations
- EGFR-TKI–sensitizing and EGFR T790M resistance mutations (correct)
- ROS1 gene mutations
What is the potential benefit of adding chemotherapy to EGFR-TKI therapy, as suggested by evidence?
What is the potential benefit of adding chemotherapy to EGFR-TKI therapy, as suggested by evidence?
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Which genetic mutations were considered in the selection of patients for the study?
Which genetic mutations were considered in the selection of patients for the study?
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