OROS Drug Delivery System Quiz
5 Questions
3 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the purpose of the small laser drilled holes in the OROS tablet?

  • To prevent the tablet from disintegrating
  • To facilitate water absorption through the semipermeable membrane
  • To allow the active drug to be pushed into the gastrointestinal tract (correct)
  • To control the drug delivery rates
  • What is a major advantage of osmotic release systems over other controlled-release mechanisms?

  • They are more cost-effective than other drug delivery systems
  • They have a longer shelf life
  • They are significantly less affected by factors such as pH, food intake, and GI motility (correct)
  • They are easier to manufacture
  • Who owns the trademark for OROS?

  • ALZA Corporation (correct)
  • Merck & Co.
  • Pfizer Inc.
  • Johnson & Johnson
  • How does the osmotic pump deliver drugs?

    <p>Using osmotic pressure to push the active drug through the laser drilled opening(s) in the tablet</p> Signup and view all the answers

    What is an inherent advantage of using an osmotic pump to deliver drugs?

    <p>Control over drug delivery rates</p> Signup and view all the answers

    Study Notes

    ### OROS Tablet Design

    • Small laser-drilled holes in OROS tablets serve as a precise entry point for water to enter.
    • This controlled water entry is crucial for the osmotic pump mechanism to function.

    Osmotic Release Systems

    • Osmotic release systems offer a significant advantage over other controlled-release methods by maintaining a consistent drug release rate, independent of external factors like pH, enzymes, or the presence of food in the digestive system.

    OROS Trademark

    • The trademark "OROS" belongs to Alza Corporation, a company specializing in drug delivery technologies.

    Osmotic Pump Mechanism

    • The osmotic pump relies on a semi-permeable membrane that allows water to enter, while the drug itself remains trapped inside.
    • As water enters the tablet, it creates pressure that pushes the drug through the laser-drilled holes, delivering a controlled and consistent dose over an extended period.

    Advantage of Osmotic Pumps

    • A notable advantage of using osmotic pumps is their ability to deliver drugs independently of gastrointestinal factors, ensuring consistent release and predictable therapeutic effects.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Description

    Test your knowledge of drug delivery systems with this quiz on Osmotic-Controlled Release Oral Delivery System (OROS). Learn about the unique features and mechanism of OROS tablets, including the semi-permeable membrane and osmotic pressure.

    Use Quizgecko on...
    Browser
    Browser