Saliva Quiz (ODS Learning Outcomes)

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Questions and Answers

What is the primary function of immunoglobulins in saliva?

  • Aid in the disposal of bacteria (correct)
  • Neutralize acids in the mouth
  • Break down starches into sugars
  • Destroy harmful bacteria by lysis

Which enzyme in saliva begins the breakdown of cooked starches?

  • Lysozyme
  • Lactoferrin
  • Phosphatase
  • Amylase (correct)

What role does lactoferrin play in saliva?

  • Increases viscosity of saliva
  • Binds free iron to inhibit bacterial metabolism (correct)
  • Promotes remineralization of dental caries
  • Destroys bacteria by breaking down their cell wall

Which waste product in saliva helps to neutralize acids?

<p>Urea (C)</p> Signup and view all the answers

What characteristic is shared by muco-proteins and glycoproteins in saliva?

<p>Both provide a viscous consistency to saliva (D)</p> Signup and view all the answers

Which cells in saliva are part of the body's defense mechanism during inflammation?

<p>White blood cells (A)</p> Signup and view all the answers

What is the function of phosphatase in saliva?

<p>To aid in calculus formation and remineralization (B)</p> Signup and view all the answers

How do commensal bacterial cells contribute to oral health?

<p>By occupying space to prevent pathogenic bacteria (A)</p> Signup and view all the answers

Which type of antibody in saliva is most effective in agglutinating bacteria?

<p>IgA (B)</p> Signup and view all the answers

What is the primary source of ammonia in saliva?

<p>Urea (D)</p> Signup and view all the answers

What is the primary function of saliva in the oral cavity?

<p>Lubricating and protecting soft tissues (C)</p> Signup and view all the answers

What is the impact of sympathetic stimulation on salivary flow?

<p>Reduces salivary flow (D)</p> Signup and view all the answers

Which ions are primarily responsible for maintaining pH levels in saliva?

<p>Sodium and potassium (B)</p> Signup and view all the answers

How does saliva contribute to the digestion process?

<p>By initiating the breakdown of cooked starches (D)</p> Signup and view all the answers

What can increase salivary flow?

<p>Mastication (C)</p> Signup and view all the answers

What is a function of the glycoproteins in saliva?

<p>Protecting against abrasion (D)</p> Signup and view all the answers

What is a significant effect of parasympathetic stimulation on the salivary glands?

<p>It enhances blood flow to the glands (B)</p> Signup and view all the answers

What gas component is found in higher levels in salivary glands and may relate to calculus formation?

<p>Carbon dioxide (C)</p> Signup and view all the answers

Which of the following factors does NOT reduce salivary flow?

<p>Teething in babies (B)</p> Signup and view all the answers

Flashcards

Immunoglobulin A (IgA)

A type of antibody found in saliva that helps protect against bacteria by clumping them together, preventing them from sticking to the mouth.

Lysozyme

An enzyme in saliva that destroys bacteria by breaking down their cell walls, causing them to burst.

Lactoferrin

A protein in saliva that binds to iron, making it unavailable for bacteria to use, thus hindering their growth.

Amylase

An enzyme in saliva that helps break down cooked starches into simpler sugars.

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Mucin

A viscous substance in saliva composed of mucoproteins and glycoproteins, giving saliva its sticky texture, which helps lubricate and protect the mouth.

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Urea

A waste product found in saliva that helps neutralize acids and maintain a balanced pH.

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White Blood Cells

A type of white blood cell found in saliva that helps fight infection by engulfing and destroying harmful bacteria.

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Commensal Bacterial Cells

Beneficial bacteria that live in the mouth and compete with harmful bacteria, preventing them from taking over.

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Desquamated Epithelial Cells

Epithelial cells that are shed from the lining of the mouth as part of the body's natural renewal process.

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Phosphatase

An enzyme found in saliva that is involved in the formation of calculus and the remineralization of teeth.

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Hormones

Chemical messengers produced by the body that regulate various functions, including those related to saliva production.

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Glycoproteins

A key component in saliva, this protein forms a protective layer on tooth enamel, acting as a barrier against acids and protecting the soft tissues of the mouth.

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Salivary Amylase

A salivary component crucial for digesting cooked starches, breaking them down into smaller particles.

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Salivary Flow

This refers to the flow of saliva, which is essential for maintaining oral health.

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Salivation

This refers to the process of producing saliva, a complex reflex involving sensory inputs and nerve signals.

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Parasympathetic Stimulation

The stimulation of salivary glands by the parasympathetic nervous system leads to increased saliva production.

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Sympathetic Stimulation

Stimulation of salivary glands by the sympathetic nervous system leads to reduced saliva production.

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Stimuli for Salivary Flow

The sight, smell, or taste of food can all trigger an increase in salivary flow.

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Factors that Reduce Salivary Flow

Conditions like diabetes, alcohol consumption, and certain medications can lead to a decrease in salivary flow.

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Study Notes

Organic Components of Saliva

  • Immunoglobulins (Ig): IgA, IgG, IgM; clump bacteria (agglutination) for removal.
  • Enzymes:
    • Lysozyme: destroys bacteria by disrupting their cell walls (lysis).
    • Lactoferrin: binds iron, inhibiting bacterial metabolism.
    • Lactoperoxidase: inhibits bacterial metabolism.
    • Amylase: begins starch digestion.
    • Ribonuclease: breaks down RNA.
    • Phosphatase: involved in calculus formation and caries remineralization.
  • Mucin: Proteins providing saliva's viscosity/stickiness (2 types).
    • Mucoproteins: >4% carbohydrate.
    • Glycoproteins: <4% carbohydrate.
  • Waste Products: Byproducts of cell metabolism.
    • Urea: neutralizes acids.
    • Uric acid.
    • Ammonia: formed from urea, raises pH.
  • Cells:
    • Desquamated epithelial cells: replaced constantly.
    • White blood cells: from gingival crevices; part of the body's defense.
    • Commensal bacteria: coexist symbiotically to prevent pathogens.
  • Food Debris: Remains of ingested food.
  • Hormones:
    • Estrogen and progesterone.

Inorganic Components of Saliva

  • Ions (mineral salts): maintain pH.
    • Sodium
    • Potassium
    • Magnesium
    • Chloride
    • Fluoride
    • Bicarbonate (buffer)
    • Sulphate
    • Hydrogen
  • Gas Components:
    • Oxygen
    • Nitrogen
    • Carbon dioxide (higher in salivary glands; possibly linked to calculus).

Functions of Saliva

  • Protection (salivary pellicle): Glycoproteins form a barrier to protect enamel from acid, lubricate and waterproof oral tissues. This helps protect against abrasion, aid speech and maintain healthy mucosa.
  • Cleansing: Serous saliva removes food and debris.
  • Buffering: Ions maintain pH unsuitable for bacterial growth.
  • Digestion: Amylase starts starch breakdown and assists in bolus formation.
  • Taste: Taste receptors detect soluble substances.
  • Antimicrobial: Proteins and Ig's destroy or prevent harmful bacteria.

Mechanism of Salivation

  • A reflex mechanism, triggered by stimuli like sight, smell, and taste.
  • Regulated by the autonomic nervous system (sympathetic and parasympathetic).
    • Sympathetic: reduces flow via vasoconstriction.
    • Parasympathetic: increases flow via vasodilation.

Factors Affecting Salivary Flow

  • Increased Flow:
    • Mastication
    • Irritants
    • Gingival conditions
    • Hunger
    • Smell/sight of food
    • Teething
  • Reduced Flow:
    • Drugs
    • Diabetes
    • Alcohol
    • Fear
    • Radiotherapy
    • Surgery

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