Podcast
Questions and Answers
What is the primary function of immunoglobulins in saliva?
What is the primary function of immunoglobulins in saliva?
- Aid in the disposal of bacteria (correct)
- Neutralize acids in the mouth
- Break down starches into sugars
- Destroy harmful bacteria by lysis
Which enzyme in saliva begins the breakdown of cooked starches?
Which enzyme in saliva begins the breakdown of cooked starches?
- Lysozyme
- Lactoferrin
- Phosphatase
- Amylase (correct)
What role does lactoferrin play in saliva?
What role does lactoferrin play in saliva?
- Increases viscosity of saliva
- Binds free iron to inhibit bacterial metabolism (correct)
- Promotes remineralization of dental caries
- Destroys bacteria by breaking down their cell wall
Which waste product in saliva helps to neutralize acids?
Which waste product in saliva helps to neutralize acids?
What characteristic is shared by muco-proteins and glycoproteins in saliva?
What characteristic is shared by muco-proteins and glycoproteins in saliva?
Which cells in saliva are part of the body's defense mechanism during inflammation?
Which cells in saliva are part of the body's defense mechanism during inflammation?
What is the function of phosphatase in saliva?
What is the function of phosphatase in saliva?
How do commensal bacterial cells contribute to oral health?
How do commensal bacterial cells contribute to oral health?
Which type of antibody in saliva is most effective in agglutinating bacteria?
Which type of antibody in saliva is most effective in agglutinating bacteria?
What is the primary source of ammonia in saliva?
What is the primary source of ammonia in saliva?
What is the primary function of saliva in the oral cavity?
What is the primary function of saliva in the oral cavity?
What is the impact of sympathetic stimulation on salivary flow?
What is the impact of sympathetic stimulation on salivary flow?
Which ions are primarily responsible for maintaining pH levels in saliva?
Which ions are primarily responsible for maintaining pH levels in saliva?
How does saliva contribute to the digestion process?
How does saliva contribute to the digestion process?
What can increase salivary flow?
What can increase salivary flow?
What is a function of the glycoproteins in saliva?
What is a function of the glycoproteins in saliva?
What is a significant effect of parasympathetic stimulation on the salivary glands?
What is a significant effect of parasympathetic stimulation on the salivary glands?
What gas component is found in higher levels in salivary glands and may relate to calculus formation?
What gas component is found in higher levels in salivary glands and may relate to calculus formation?
Which of the following factors does NOT reduce salivary flow?
Which of the following factors does NOT reduce salivary flow?
Flashcards
Immunoglobulin A (IgA)
Immunoglobulin A (IgA)
A type of antibody found in saliva that helps protect against bacteria by clumping them together, preventing them from sticking to the mouth.
Lysozyme
Lysozyme
An enzyme in saliva that destroys bacteria by breaking down their cell walls, causing them to burst.
Lactoferrin
Lactoferrin
A protein in saliva that binds to iron, making it unavailable for bacteria to use, thus hindering their growth.
Amylase
Amylase
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Mucin
Mucin
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Urea
Urea
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White Blood Cells
White Blood Cells
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Commensal Bacterial Cells
Commensal Bacterial Cells
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Desquamated Epithelial Cells
Desquamated Epithelial Cells
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Phosphatase
Phosphatase
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Hormones
Hormones
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Glycoproteins
Glycoproteins
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Salivary Amylase
Salivary Amylase
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Salivary Flow
Salivary Flow
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Salivation
Salivation
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Parasympathetic Stimulation
Parasympathetic Stimulation
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Sympathetic Stimulation
Sympathetic Stimulation
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Stimuli for Salivary Flow
Stimuli for Salivary Flow
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Factors that Reduce Salivary Flow
Factors that Reduce Salivary Flow
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Study Notes
Organic Components of Saliva
- Immunoglobulins (Ig): IgA, IgG, IgM; clump bacteria (agglutination) for removal.
- Enzymes:
- Lysozyme: destroys bacteria by disrupting their cell walls (lysis).
- Lactoferrin: binds iron, inhibiting bacterial metabolism.
- Lactoperoxidase: inhibits bacterial metabolism.
- Amylase: begins starch digestion.
- Ribonuclease: breaks down RNA.
- Phosphatase: involved in calculus formation and caries remineralization.
- Mucin: Proteins providing saliva's viscosity/stickiness (2 types).
- Mucoproteins: >4% carbohydrate.
- Glycoproteins: <4% carbohydrate.
- Waste Products: Byproducts of cell metabolism.
- Urea: neutralizes acids.
- Uric acid.
- Ammonia: formed from urea, raises pH.
- Cells:
- Desquamated epithelial cells: replaced constantly.
- White blood cells: from gingival crevices; part of the body's defense.
- Commensal bacteria: coexist symbiotically to prevent pathogens.
- Food Debris: Remains of ingested food.
- Hormones:
- Estrogen and progesterone.
Inorganic Components of Saliva
- Ions (mineral salts): maintain pH.
- Sodium
- Potassium
- Magnesium
- Chloride
- Fluoride
- Bicarbonate (buffer)
- Sulphate
- Hydrogen
- Gas Components:
- Oxygen
- Nitrogen
- Carbon dioxide (higher in salivary glands; possibly linked to calculus).
Functions of Saliva
- Protection (salivary pellicle): Glycoproteins form a barrier to protect enamel from acid, lubricate and waterproof oral tissues. This helps protect against abrasion, aid speech and maintain healthy mucosa.
- Cleansing: Serous saliva removes food and debris.
- Buffering: Ions maintain pH unsuitable for bacterial growth.
- Digestion: Amylase starts starch breakdown and assists in bolus formation.
- Taste: Taste receptors detect soluble substances.
- Antimicrobial: Proteins and Ig's destroy or prevent harmful bacteria.
Mechanism of Salivation
- A reflex mechanism, triggered by stimuli like sight, smell, and taste.
- Regulated by the autonomic nervous system (sympathetic and parasympathetic).
- Sympathetic: reduces flow via vasoconstriction.
- Parasympathetic: increases flow via vasodilation.
Factors Affecting Salivary Flow
- Increased Flow:
- Mastication
- Irritants
- Gingival conditions
- Hunger
- Smell/sight of food
- Teething
- Reduced Flow:
- Drugs
- Diabetes
- Alcohol
- Fear
- Radiotherapy
- Surgery
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