Podcast
Questions and Answers
The compound CH3CH2NHCH3 is classified as a?
The compound CH3CH2NHCH3 is classified as a?
- Primary amine
- Tertiary amine
- Quaternary amine
- Secondary amine (correct)
The compound CH3CH2NH2 is classified as a?
The compound CH3CH2NH2 is classified as a?
- Tertiary amine
- Secondary amine
- Quaternary amine
- Primary amine (correct)
Which of the following compounds is an amine?
Which of the following compounds is an amine?
- C6H5N
- CH3OH
- C2H5OH
- (CH3CH2)2NH (correct)
What is the name of the compound HNCH3-benzene ring-Br?
What is the name of the compound HNCH3-benzene ring-Br?
Aminobenzene is properly known as?
Aminobenzene is properly known as?
What is the name of the compound CH3-NCH2CH3-CH3?
What is the name of the compound CH3-NCH2CH3-CH3?
Name the compound CH3-NH-CH3.
Name the compound CH3-NH-CH3.
Amines contain the element?
Amines contain the element?
In what kind of amine is the nitrogen directly bonded to two carbon atoms?
In what kind of amine is the nitrogen directly bonded to two carbon atoms?
When naming amines according to the IUPAC system, the -e in the corresponding alkane is replaced with?
When naming amines according to the IUPAC system, the -e in the corresponding alkane is replaced with?
Aniline is a(n)?
Aniline is a(n)?
What prefix is used to show that a small alkyl group is attached to the nitrogen of aniline and not to the aromatic ring?
What prefix is used to show that a small alkyl group is attached to the nitrogen of aniline and not to the aromatic ring?
How many alkyl substituents does N-ethyl-N-methylaniline have?
How many alkyl substituents does N-ethyl-N-methylaniline have?
Which of the following compounds CANNOT form hydrogen bonds with water?
Which of the following compounds CANNOT form hydrogen bonds with water?
What relation does the boiling point of an amine have to a similar hydrocarbon?
What relation does the boiling point of an amine have to a similar hydrocarbon?
Amines can form ____ bonds with other molecules.
Amines can form ____ bonds with other molecules.
What kind of amine can NOT form hydrogen bonds?
What kind of amine can NOT form hydrogen bonds?
Amines are?
Amines are?
The odor of an amine can be neutralized with?
The odor of an amine can be neutralized with?
Choline is a quaternary ammonium compound with a ___ charge on the nitrogen.
Choline is a quaternary ammonium compound with a ___ charge on the nitrogen.
In what form are amine-containing drugs often administered?
In what form are amine-containing drugs often administered?
What kind of pharmacologic activity is found in the amines Procaine and Lidocaine?
What kind of pharmacologic activity is found in the amines Procaine and Lidocaine?
What are alkaloids?
What are alkaloids?
Identify the heterocyclic amine in the choices below.
Identify the heterocyclic amine in the choices below.
Among the choices below, identify the heterocyclic amine found in DNA.
Among the choices below, identify the heterocyclic amine found in DNA.
Nicotine, coniine, quinine, atropine, and morphine are all examples of?
Nicotine, coniine, quinine, atropine, and morphine are all examples of?
Procaine and Lidocaine were developed by modifying the structure of?
Procaine and Lidocaine were developed by modifying the structure of?
Physiologically active nitrogen-containing compounds produced by plants are called?
Physiologically active nitrogen-containing compounds produced by plants are called?
Which of the following is NOT an alkaloid?
Which of the following is NOT an alkaloid?
What functional group is always found in alkaloids (such as caffeine, nicotine, and digitalis)?
What functional group is always found in alkaloids (such as caffeine, nicotine, and digitalis)?
Cyclic compounds that contain a nitrogen atom are called?
Cyclic compounds that contain a nitrogen atom are called?
What is the major functional group in the following compound? O=CH3CNHCH3
What is the major functional group in the following compound? O=CH3CNHCH3
What is the name of this compound? O=CNHCH2CH3-Hexagon shape.
What is the name of this compound? O=CNHCH2CH3-Hexagon shape.
One name for this compound is O=CH3CH2-C-NH-CH2CH3.
One name for this compound is O=CH3CH2-C-NH-CH2CH3.
Which chemical class does phenobarbital belong to?
Which chemical class does phenobarbital belong to?
What kind of compound is urea?
What kind of compound is urea?
What is the chemical classification of the barbiturate sedatives?
What is the chemical classification of the barbiturate sedatives?
Amines having fewer than ___ carbons are generally water soluble.
Amines having fewer than ___ carbons are generally water soluble.
Aniline is the IUPAC approved name for aminobenzene.
Aniline is the IUPAC approved name for aminobenzene.
Aniline is a primary amine.
Aniline is a primary amine.
Ethylmethylamine is a tertiary amine.
Ethylmethylamine is a tertiary amine.
The amine functional group is rarely found in pharmacologically active compounds.
The amine functional group is rarely found in pharmacologically active compounds.
Primary amines contain two carbon-containing groups bonded to the nitrogen atom.
Primary amines contain two carbon-containing groups bonded to the nitrogen atom.
Amines do not form hydrogen bonds.
Amines do not form hydrogen bonds.
Amines do not ionize in water.
Amines do not ionize in water.
Amines act as weak acids by accepting protons from water.
Amines act as weak acids by accepting protons from water.
Amine salts are odorless and usually highly water soluble.
Amine salts are odorless and usually highly water soluble.
Quinine is an alkaloid used for treatment of malaria.
Quinine is an alkaloid used for treatment of malaria.
Heterocyclic amines contain a nitrogen atom in a ring.
Heterocyclic amines contain a nitrogen atom in a ring.
Aspirin substitutes may contain amide rather than ester functional groups.
Aspirin substitutes may contain amide rather than ester functional groups.
Amides are bases.
Amides are bases.
The compound CH3CH2NHCH3 is an?
The compound CH3CH2NHCH3 is an?
When acetic acid reacts with ammonia, NH3, the reaction is called amidation and yields?
When acetic acid reacts with ammonia, NH3, the reaction is called amidation and yields?
What is the major functional group in the following compound? O=CH3CNHCH3.
What is the major functional group in the following compound? O=CH3CNHCH3.
In the formation of N-ethylacetamide, the reactants are?
In the formation of N-ethylacetamide, the reactants are?
What is the name of the amide formed in the reaction of benzoic acid and ethylamine?
What is the name of the amide formed in the reaction of benzoic acid and ethylamine?
What is the name of the amide formed in the reaction of O=CH3CH2CNHCH3?
What is the name of the amide formed in the reaction of O=CH3CH2CNHCH3?
The reaction of butanoic acid and dimethylamine gives?
The reaction of butanoic acid and dimethylamine gives?
Amides are derivatives of ___ and ___.
Amides are derivatives of ___ and ___.
Which of the following is the reaction for the acid hydrolysis of N-methylacetamide?
Which of the following is the reaction for the acid hydrolysis of N-methylacetamide?
Which of the following is the reaction for the base hydrolysis of N-ethylformamide?
Which of the following is the reaction for the base hydrolysis of N-ethylformamide?
The compound O=CH3CH2CNHCH3 is an?
The compound O=CH3CH2CNHCH3 is an?
The correct name for O=HCNHCH2CH3 is?
The correct name for O=HCNHCH2CH3 is?
With the correct choice of acid, acid hydrolysis of acetamide could produce?
With the correct choice of acid, acid hydrolysis of acetamide could produce?
With the correct choice of acid, the product of the acid hydrolysis of N-methylbenzamide could be?
With the correct choice of acid, the product of the acid hydrolysis of N-methylbenzamide could be?
What pharmacologically active amine is responsible for the signs and symptoms encountered in an allergic reaction?
What pharmacologically active amine is responsible for the signs and symptoms encountered in an allergic reaction?
Which of the following is not a neurotransmitter?
Which of the following is not a neurotransmitter?
A neurotransmitter?
A neurotransmitter?
In response to allergic reactions or injury to cells, the body increases the production of?
In response to allergic reactions or injury to cells, the body increases the production of?
Study Notes
Amines Classification
- CH3CH2NHCH3 is a secondary amine.
- CH3CH2NH2 is a primary amine.
- (CH3CH2)2NH is classified as an amine.
- Dimethylamine is designated as CH3-NH-CH3.
Names and Structures of Amines
- N-methyl-3-bromoaniline is derived from HNCH3-benzene ring-Br.
- Aminobenzene is formally referred to as aniline.
- Ethyldimethylamine is represented as CH3-NCH2CH3-CH3.
Properties and Functional Groups
- Amines are nitrogen-containing compounds capable of forming hydrogen bonds.
- Tertiary amines, like (CH3CH2)3N, do not form hydrogen bonds.
- Primary amines contain one carbon-containing group bonded to nitrogen, while secondary amines have two.
- The characteristic functional group in alkaloids is an amine.
Reaction and Hydrolysis
- Ethylamine in water creates ethylammonium hydroxide.
- Diethylamine reacts with HCl to yield diethylammonium chloride.
- The hydrolysis of amides can produce corresponding acids and amines when treated with acids or bases.
Biological Significance of Amines
- Amines can act as Bronsted-Lowry bases.
- Quaternary ammonium compounds like choline have a positive nitrogen charge.
- Histamine, an active amine, is associated with allergic reactions.
Medicinal Chemistry
- Amine salts are commonly used in drug formulations due to their increased solubility.
- Alkaloids, including nicotine, quinine, and morphine, are biologically active nitrogen compounds.
- Local anesthetics such as Procaine and Lidocaine are derived from modifications of cocaine.
Miscellaneous
- Heterocyclic compounds are cyclic structures containing nitrogen.
- Amides are derivatives of amines and carboxylic acids, and are involved in various chemical reactions.
- Acid and base hydrolysis of amides produces corresponding acids and amines or ammonium salts.
Boiling Points and Solubility
- Amines generally have higher boiling points than similar hydrocarbons due to hydrogen bonding.
- Water solubility of amines decreases with an increasing number of carbon atoms; typically, amines with fewer than six carbon atoms are soluble.
True/False Statements
- Aniline is confirmed as a primary aromatic amine.
- Ethylmethylamine is not a tertiary amine, hence that statement is false.
- Amine salts and heterocyclic amines like pyrrolidine possess physiological significance and are correctly identified.
Summary of Reactions
- Amidation between acetic acid and ammonia yields acetamide.
- The reaction between benzoic acid and ethylamine produces N-ethylbenzamide, showcasing the amide functionality.
- Hydrolysis reactions allow amides to revert to their respective acids and amines under the right conditions.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Test your knowledge of amines, including primary and secondary classifications, with these informative flashcards from Chapter 18. This quiz focuses on recognizing and naming various amines and their structures. Perfect for students studying organic chemistry.
