Podcast
Questions and Answers
What is a characteristic of aromatic rings that enables them to participate in van der Waals interactions with the active site?
What is a characteristic of aromatic rings that enables them to participate in van der Waals interactions with the active site?
- Their capacity to form covalent bonds with the active site
- Their planar and hydrophobic structure (correct)
- Their ability to form hydrogen bonds with the active site
- Their ability to form induced dipoles with the active site
Why does the cyclohexyl ring not bind well to the active site?
Why does the cyclohexyl ring not bind well to the active site?
- Due to the presence of axial protons that can interact strongly with the active site
- Due to the planar shape of the cyclohexyl ring
- Due to the ability of the cyclohexyl ring to form hydrogen bonds with the active site
- Due to the steric bulk of the cyclohexyl ring that prevents it from fitting into the narrow binding slot (correct)
What is the characteristic of alkenes that makes them easier to reduce than aromatic rings?
What is the characteristic of alkenes that makes them easier to reduce than aromatic rings?
- Their ability to form hydrogen bonds with the active site
- Their higher energy state compared to aromatic rings (correct)
- Their planar and hydrophobic structure
- Their ability to form induced dipoles with the active site
What type of interaction is possible between an aromatic ring and an ammonium or quaternary ammonium ion?
What type of interaction is possible between an aromatic ring and an ammonium or quaternary ammonium ion?
What is the role of the C=O group in the electronic interaction of esters?
What is the role of the C=O group in the electronic interaction of esters?
Why are phenols effective as hydrogen bond acceptors?
Why are phenols effective as hydrogen bond acceptors?
What is the difference between axial and equatorial protons in the context of cyclohexane rings?
What is the difference between axial and equatorial protons in the context of cyclohexane rings?
What type of interaction is possible between an amine and the active site?
What type of interaction is possible between an amine and the active site?
Why are esters less effective as hydrogen bond acceptors compared to alcohols?
Why are esters less effective as hydrogen bond acceptors compared to alcohols?
What is the characteristic of heteroaromatic amines that enables them to participate in van der Waals interactions with the active site?
What is the characteristic of heteroaromatic amines that enables them to participate in van der Waals interactions with the active site?
