Orexin Receptor Antagonists and Peptides in Hypothalamic Neurons Quiz

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Questions and Answers

Which part of the brain contains specific neurons that produce Orexin A and B peptides?

  • Thalamus
  • Hypothalamus (correct)
  • Hippocampus
  • Amygdala

What is the role of Orexin receptor antagonists like Suvorexant and Almorexant?

  • Regulate appetite
  • Induce sleep
  • Promote wakefulness (correct)
  • Enhance memory retention

What is the primary function of Orexin A and B peptides?

  • Wakefulness control (correct)
  • Appetite suppression
  • Memory consolidation
  • Stress regulation

What is the relationship between Orexin and anxiety regulation?

<p>Orexin indirectly impacts anxiety through sleep regulation (A)</p> Signup and view all the answers

Which of the following is a possible effect of Orexin receptor antagonists like Suvorexant?

<p>Reduced appetite (B)</p> Signup and view all the answers

What is a disorder characterized by day-time sleepiness and cataplexy?

<p>Narcolepsy (B)</p> Signup and view all the answers

Which type of neurons are associated with narcolepsy?

<p>Orexin neurons (A)</p> Signup and view all the answers

Which class of drugs are used to treat anxiety disorders?

<p>SSRIs (D)</p> Signup and view all the answers

What type of drugs act as orexin receptor antagonists?

<p>Hypnotics (A)</p> Signup and view all the answers

What is the mechanism of action of Orexin receptor antagonists like Suvorexant and Almorexant?

<p>Having GABA mimetic and facilitatory actions (D)</p> Signup and view all the answers

Which neurotransmitter system do orexin neurons primarily interact with?

<p>Histamine (B)</p> Signup and view all the answers

Which condition is Barbiturates like Phenobarbitone commonly used to treat?

<p>Grand mal epilepsy (A)</p> Signup and view all the answers

What is a common adverse effect associated with Barbiturates?

<p>Respiratory depression (D)</p> Signup and view all the answers

Which receptor do Orexin receptor antagonists act on?

<p>Orexin receptor (B)</p> Signup and view all the answers

In what context are Barbiturates like Thiopentone primarily used?

<p>Induction of anesthesia (D)</p> Signup and view all the answers

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