Oral and Craniofacial Development Overview

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29 Questions

What is the central question of developmental biology?

How is the development of different organ systems coordinated?

What is the term for the process of acquiring an organized form?

Morphogenesis

What is the concept that an embryo's development repeats its evolutionary past?

Ontogeny recapitulates phylogeny

What is the name of the scientist who proposed the idea of 'Ontogeny recapitulates phylogeny'?

Haeckel

What is the term for the study of the structure and organization of embryos?

Anatomical embryology

What is the term for the process by which tissues and organs form 'de novo'?

Epigenesis

What makes the chick embryo a popular biological research model?

All of the above

What is a key benefit of using chick embryos to study developmental processes?

The ability to visualize complex processes in real-time

What is a significant advantage of using chick embryos to study human genetic diseases?

The genetic similarity between chick and human genomes

What have experiments in chicken helped to elucidate?

The underlying mechanisms of human genetic diseases

What is a characteristic of chick embryo development that makes it similar to human development?

The development of a dorsal-ventral neural tube pattern

What can be examined using chick embryos?

Several complex processes, including cell migration, cell-cell communication, and tissue morphogenesis

What is a characteristic of zebrafish that makes them useful for inducing mutations?

They can tolerate higher levels of chemical mutagens

What type of cells direct the growth and development of our faces?

Neural Crest cells

What is the term for the process of continuous tooth formation and replacement?

Dyphodont

What is the term for the formation of supernumerary teeth as a third dentition?

Cleidocranial dysplasia

What type of cells are involved in the formation of cranial teeth?

Odontoblasts

What makes Zebrafish embryos ideal for studying early development?

They are fertilized and develop outside the mother's body.

What percentage of genes do Zebrafish share with humans?

70%

What is a unique feature of Zebrafish embryos and larvae that makes it easy to study their development?

They are transparent.

Why are Zebrafish easier to use in research compared to rodents?

They are easier to house and care for.

What is an advantage of using Zebrafish in research compared to other model organisms?

They produce lots of offspring.

How can genetic changes be introduced into Zebrafish embryos?

Through chemical mutagens in the water.

What is the approximate incidence of ectodermal dysplasia syndromes?

1:1500 births

Which gene is associated with oligodontia and colorectal cancer?

AXIN2

What is the name of the gene that is mutated in hypohidrotic ectodermal dysplasia?

EDA

Which of the following is NOT a characteristic feature of hypohidrotic ectodermal dysplasia?

Excessive sweating

What is the name of the syndrome that is characterized by ectodermal dysplasia, ectrodactyly, and cleft palate?

EEC syndrome

What is the name of the gene that is associated with bone hypoplasia and Runx2?

RUNX2

Learn about the development of a complex organism from a single cell, the fertilised egg. This quiz covers the process of progressive change of organis, embryo development, and coordinated development of different organ systems.

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