Optimizing Insulin Therapy for Diabetes Patients
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Questions and Answers

What is the primary reason insulin is underutilized as a glucose-lowering therapy?

  • Lack of data on its effectiveness
  • Insufficient tailoring of insulin dosing
  • Unavailability of basal bolus therapy
  • Patient fear and provider ignorance (correct)

    • What is the potential benefit of smart insulin delivery in diabetes care?

  • Improving exogenous insulin replacement
  • Preventing hypo and hyperglycemia (correct)
  • Increasing cardiovascular mortality
  • Reducing the need for premixed insulin

    • What is the focus of future developments in insulin management?

  • Improving the convenience and accuracy of exogenous insulin replacement (correct)
  • Increasing the use of oral hypoglycemic agents
  • Reducing the use of SGLT-2 inhibitors
  • Developing newer insulin dosing methods

    • What is the benefit of SGLT-2 inhibitors in diabetes patients?

    <p>Reducing cardiac events and heart failure hospitalization</p> Signup and view all the answers

    What is the advantage of tailored insulin dosing using exogenous and endogenous insulin values?

    <p>Reducing premixed insulin usage and returning to basal bolus therapy</p> Signup and view all the answers

    What is the challenge posed by the current diabetes and obesity epidemics?

    <p>Creating an increasingly complex population of patients with diabetes and concurrent comorbidities</p> Signup and view all the answers

    What is the primary advantage of smart insulin delivery?

    <p>Achieving near-normal glycemia without hypoglycemia or adverse effects</p> Signup and view all the answers

    What is the main challenge in achieving postprandial blood sugars in a desirable target range for individual patients?

    <p>All of the above and more</p> Signup and view all the answers

    What is the primary goal of the paradigm shift from fixed prandial doses to insulin:carbohydrate ratio dosing?

    <p>Achieving good postprandial glycemic control</p> Signup and view all the answers

    What is the advantage of Continuous Glucose Monitoring (CGM) over self-monitoring blood glucose (SMBG)?

    <p>CGM provides a continuous glucose profile throughout the day</p> Signup and view all the answers

    What is the primary limitation of self-monitoring blood glucose (SMBG)?

    <p>The delayed action from the test result</p> Signup and view all the answers

    What is the purpose of Artificial Intelligence (AI) in insulin dosing?

    <p>To optimize insulin dosing and glycemic control</p> Signup and view all the answers

    What is a potential benefit of future insulin dosing approaches?

    <p>Improved glucose control</p> Signup and view all the answers

    What is the purpose of the Stanford Artificial Pancreas Project's Automated Multiparametric Intelligent Control system (AMPIC)?

    <p>To optimize insulin dosing and glycemic control</p> Signup and view all the answers

    What is the result of a recent meta-analysis on the use of Continuous Glucose Monitoring (CGM)?

    <p>CGM has a moderate but significant mean A1C lowering effect</p> Signup and view all the answers

    What is the traditional rule of thumb for insulin dosing in type 1 diabetes?

    <p>0.6 units/kg/day total dose</p> Signup and view all the answers

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