Podcast
Questions and Answers
What is the purpose of using OsO4 in the hydroxylation reaction of alkenes?
What is the purpose of using OsO4 in the hydroxylation reaction of alkenes?
- To prevent further oxidation of the glycol
- To avoid using expensive reagents
- To give a higher yield (correct)
- To make the reaction less toxic
Why are gem diols unstable in aqueous solutions?
Why are gem diols unstable in aqueous solutions?
- They react with water to form stable cyclic compounds
- Due to the presence of water promoting dehydration to form aldehydes or ketones (correct)
- Gem diols are inherently unstable compounds
- Because aqueous solutions catalyze their conversion to alkenes
In the Pinacol-Pinacolone rearrangement, what is the main purpose of the protonation step?
In the Pinacol-Pinacolone rearrangement, what is the main purpose of the protonation step?
- To promote the 1,2-rearrangement
- To initiate the formation of carbocation (correct)
- To catalyze the dehydration of glycols
- To stabilize the gem diols
Why is OsO4 used in catalytic amounts in the hydroxylation reaction of alkenes?
Why is OsO4 used in catalytic amounts in the hydroxylation reaction of alkenes?
What is the outcome of treating epoxides with aqueous acid?
What is the outcome of treating epoxides with aqueous acid?
Which compound is formed when gem diols dehydrate in the absence of water?
Which compound is formed when gem diols dehydrate in the absence of water?
What role does sodium bisulfate play in the OsO4-catalyzed formation of diols from alkenes?
What role does sodium bisulfate play in the OsO4-catalyzed formation of diols from alkenes?
What is the primary reason for using catalytic amounts of osmium tetraoxide (OsO4) in reactions?
What is the primary reason for using catalytic amounts of osmium tetraoxide (OsO4) in reactions?
'The alkene is treated with osmium tetraoxide, followed by sodium bisulfate' - What is the purpose of treating with sodium bisulfate in this sequence?
'The alkene is treated with osmium tetraoxide, followed by sodium bisulfate' - What is the purpose of treating with sodium bisulfate in this sequence?
What is the consequence of using KMnO4 for oxidation of alkenes?
What is the consequence of using KMnO4 for oxidation of alkenes?
