OPT 2064 Ocular Biology: Retina Histology Overview

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31 Questions

What is the main function of the retina?

Processing electromagnetic energy in the retinal image into neural signals

Which part of the eye supports the retina only at two regions?

Vitreous humor

Which layer of the retina is firmly attached at two regions, around the optic disc and at the ora serrata?

Pigment epithelium

What is the average thickness of the retina?

200μm

Which layer of the retina forms a junction with the vitreous?

Internal limiting membrane

What is the total area of the retina?

950mm2

What is the function of the retinal pigment epithelium (RPE) cells?

To absorb stray light and provide a pathway for metabolites to the receptors

What is the structure that links the outer segment to the inner segment of the photoreceptor cell?

Cilium

What is the total length of the outer & inner segments of both rods & cones?

60μm

What is the composition of the outer segments in cones?

Series of discs formed by infolding of the cell membrane

What fills all the extracellular space in the layer containing the cell membrane of the receptors and Müller cell membranes?

Muco-polysaccharide ground substance

What is the function of the zonular adhesions linking the cell membrane of the receptors and Müller cell membranes?

Provide mechanical stability to the tips of the receptors

What is present in the cell body of retinal pigment epithelium (RPE) cells?

Large amount of endoplasmic reticulum, mitochondria, & melanin granules

What does Bruch's membrane do?

Forms part of the basement membrane that adheres to RPE cells

Where do rods replace cones entirely?

At the ora-serrata

What is the structure that extends from the ora-serrata to the edge of the optic disc?

External limiting membrane

What is the function of the extraocular muscles?

To enable high-velocity ocular movements

Which muscle is responsible for moving the eye laterally?

Lateral rectus

How does a muscle contraction initiate in the extraocular muscles?

Depolarization of the sarcolemma triggered by a nerve impulse

What provides for the precise fine motor control of extraocular muscles?

Innervation of 3 to 10 fibers by each axon

What characterizes the extraocular muscles compared to skeletal muscles?

Denser blood supply and delicate connective tissue sheaths

What is the velocity of saccades, as supported by the extraocular muscles?

Up to 1000 degrees per second

What is the first step in the sliding ratchet model of muscle contraction?

Calcium release

Which event occurs after the binding of calcium ions to the troponin-tropomyosin complex in muscle contraction?

ATP breakdown

What is the last step in the sliding ratchet model of muscle contraction?

Reset

Which of the following represents the anatomical sequence of the spiral of Tillaux involving the extraocular muscles?

Medial rectus, inferior rectus, lateral rectus, superior rectus

What is the function of the largest extraocular muscle, the medial rectus?

Moves the eye medially (adducts)

What does ATP attachment enable in muscle contraction?

Formation of cross-bridges

What initiates the exposure of an active site on the actin protein in muscle contraction?

Calcium release

In muscle contraction, what causes the head to tilt towards the shaft of the myosin filament?

ATP breakdown

Which structure marks the start and end points of the spiral of Tillaux involving extraocular muscles?

"Limbus"

Explore the general view and histology of the retina, the innermost nervous tunic of the eye, including its color, area, thickness variations, and attachment points. Gain insight into the biology of the retina in ocular studies.

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