Questions and Answers
What is the trade name of Oprelvekin?
What is the pharmacological classification of Oprelvekin?
recombinant IL-11
What is the action of Oprelvekin?
Stimulates the bone marrow to produce platelets
What are the uses of Oprelvekin?
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What are some side effects of Oprelvekin?
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Oprelvekin has a black box warning for allergic or hypersensitivity reactions.
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What nursing interventions are recommended when administering Oprelvekin?
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Study Notes
Oprelvekin Overview
- Trade name: Neumega
- Classification: Recombinant interleukin-11 (IL-11)
Drug Action
- Stimulates bone marrow to increase platelet production.
- Essential for preventing low platelet counts.
Indications
- Used to prevent severe thrombocytopenia.
- Aims to reduce platelet transfusion needs in adults with non-myeloid cancers undergoing myelosuppressive chemotherapy.
Common Side Effects
- Local injection site reactions, headaches, dizziness, nausea, and vomiting (N/V).
- Swelling due to water retention, predominantly in hands, feet, and ankles.
- Potential for shortness of breath.
Critical Warnings
- Black Box Warning: Risk of allergic or hypersensitivity reactions, including anaphylaxis.
- Discontinue treatment immediately if allergic reactions occur.
- Educate patients on recognizing signs of hypersensitivity, such as wheezing, chest tightness, rashes, itching, fever, and swelling.
Nursing Considerations
- Perform baseline assessments of cardiac and pulmonary functions prior to administration.
- Rotate injection sites for subcutaneous administration to minimize local reactions.
- Monitor for bleeding and assess laboratory values, particularly complete blood count (CBC).
- Observe patients during and after treatment for potential cumulative effects of the medication.
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Explore the key concepts related to Oprelvekin through these flashcards. This quiz covers trade names, pharmaceutical classifications, mechanisms of action, and uses of the drug. Ideal for medical students and healthcare professionals seeking to reinforce their knowledge.
