Podcast
Questions and Answers
Which condition would be considered a contraindication for the use of opioid agonists?
Which condition would be considered a contraindication for the use of opioid agonists?
- Respiratory dysfunction (correct)
- Severe acute pain
- Relief of chronic pain
- Analgesia during anesthesia
A patient with a history of delirium tremens requires strong analgesia. Which factor would be most important to consider regarding the use of opioid agonists?
A patient with a history of delirium tremens requires strong analgesia. Which factor would be most important to consider regarding the use of opioid agonists?
- Opioids will help treat the underlying cause of delirium tremens
- Delirium tremens is listed as a contraindication for opioid use (correct)
- Patients with delirium tremens can only be treated with synthetic opioids
- Opioids are always safe in patients with delirium tremens
What is the primary mechanism by which opioid agonists produce analgesia?
What is the primary mechanism by which opioid agonists produce analgesia?
- Enhancing the release of dopamine in the spinal cord
- Blocking pain signal transmission in peripheral nerves
- Interacting with specific opioid receptor sites (mostly μ receptors) in the CNS (correct)
- Stimulating alpha-adrenergic receptors in the brain
A patient reports dizziness and altered mental status after receiving an opioid agonist. What is the most likely cause of these symptoms?
A patient reports dizziness and altered mental status after receiving an opioid agonist. What is the most likely cause of these symptoms?
Which of the following is a common indication for opioid agonist administration?
Which of the following is a common indication for opioid agonist administration?
Which of the following opioid agonists is classified as a synthetic opioid?
Which of the following opioid agonists is classified as a synthetic opioid?
Which of the following signs might indicate an adverse effect of an opioid agonist?
Which of the following signs might indicate an adverse effect of an opioid agonist?
Which patient population requires extra caution when considering opioid agonists due to a listed contraindication?
Which patient population requires extra caution when considering opioid agonists due to a listed contraindication?
A patient with a history of asthma is prescribed an opioid agonist for pain management. What potential risk should be closely monitored?
A patient with a history of asthma is prescribed an opioid agonist for pain management. What potential risk should be closely monitored?
Which opioid agonist is classified as a semi-synthetic opioid (derivative)?
Which opioid agonist is classified as a semi-synthetic opioid (derivative)?
Flashcards
Opioid Agonist Action
Opioid Agonist Action
Opioid agonists bind to specific opioid receptor sites, primarily μ receptors, in the CNS.
Indications for Opioid Agonists
Indications for Opioid Agonists
Provide relief from severe acute or chronic pain and analgesia during anesthesia.
Adverse Effects of Opioid Agonists
Adverse Effects of Opioid Agonists
CNS depression, hypotension, dyspnea, dizziness and altered mental status.
Opioid Agonists Contraindications
Opioid Agonists Contraindications
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Natural Opioids
Natural Opioids
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Synthetic Opioids
Synthetic Opioids
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Semi-Synthetic Opioids
Semi-Synthetic Opioids
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Study Notes
- Opioid agonists work in the CNS, primarily at mu receptors.
- These agonists produce analgesia, sedation, and a sense of well-being.
Contraindications
- Should not be used in patients with CNS depression or GI obstruction.
- Contraindicated in respiratory dysfunction, asthma, or emphysema.
- Use is cautioned against with recent GI or GU surgery or head injury.
- Alcohol use disorder, delirium tremens, or cerebral vascular disease are contraindications.
- Avoid use during pregnancy, labor, or lactation.
Indications
- Used for the relief of severe acute or chronic pain.
- Provides analgesia during anesthesia.
Adverse Effects
- Can cause CNS depression.
- May cause hypotension, dyspnea, or dizziness.
- It can also lead to altered mental status.
Names of Opioid Agonists
- Natural opioids include morphine and codeine.
- Synthetic opioids include fentanyl, tramadol, and methadone.
- Semi-synthetic opioids include hydrocodone, oxycodone, hydromorphone, oxymorphone, and heroin.
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