Ophthalmology Phlyctenular Conjunctivitis

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Questions and Answers

What initial recommendation is made for patients with bleeding disorders?

  • Administer NSAIDs for pain relief
  • Perform emergency surgery immediately
  • Start anticoagulant therapy
  • Order CBC, PT, PTT for bleeding disorders (correct)

Which of the following is NOT suggested in the management of bleeding disorders?

  • Lubricants
  • Use of NSAIDs (correct)
  • Patient reassurance
  • Referral to an internist if a blood disorder is suspected

Ocular Cicatricial Pemphygoid primarily affects which part of the body?

  • The brain
  • The digestive tract
  • The mucous membranes (correct)
  • The skin

At what age is Ocular Cicatricial Pemphygoid most commonly diagnosed?

<p>After the age of 55 (A)</p> Signup and view all the answers

Which systemic treatment options are recommended for Ocular Cicatricial Pemphygoid?

<p>Oral steroids and Dapsone (A)</p> Signup and view all the answers

What is the primary cause of blister formation in Ocular Cicatricial Pemphygoid?

<p>Autoimmune reaction (D)</p> Signup and view all the answers

Which sign is commonly associated with Ocular Cicatricial Pemphygoid?

<p>Mucous membrane vesicles (D)</p> Signup and view all the answers

What stage of Ocular Cicatricial Pemphygoid involves conjunctival shrinkage and its associated complications?

<p>Stage II (C)</p> Signup and view all the answers

Which of the following drugs is NOT associated with drug-induced Ocular Cicatricial Pemphygoid?

<p>Dapsone (B)</p> Signup and view all the answers

What is a potential complication of blisters in conjunctiva due to Ocular Cicatricial Pemphygoid?

<p>Vision loss (D)</p> Signup and view all the answers

Which of the following antibiotics is NOT recommended for severe staphylococcal infections?

<p>Ciprofloxacin 500 mg BID x 2-4 weeks (B)</p> Signup and view all the answers

What is the age demographic most commonly affected by Superior Limbic Keratoconjunctivitis (SLK)?

<p>Middle-aged women aged 20-55 (A)</p> Signup and view all the answers

Which condition is associated with over 50% of patients suffering from Superior Limbic Keratoconjunctivitis?

<p>Keratoconjunctivitis sicca (KCS) (B)</p> Signup and view all the answers

What is the primary characteristic of Superior Limbic Keratoconjunctivitis?

<p>Chronic, progressive inflammation (C)</p> Signup and view all the answers

What is the suggested cause of the etiology of Superior Limbic Keratoconjunctivitis?

<p>Mechanical trauma and friction from eyelids (B)</p> Signup and view all the answers

Which oral antibiotic class is noted as best for reducing collagenases in inflammation?

<p>Tetracyclines (C)</p> Signup and view all the answers

What is a common associated condition in patients with Superior Limbic Keratoconjunctivitis?

<p>Thyroid disease (A)</p> Signup and view all the answers

What treatment is NOT part of the regimen for severe staph infections?

<p>Topical antihistamines (A)</p> Signup and view all the answers

What is a treatment regimen for severe staphylococcal infections involving topical medication?

<p>Líd scrubs and Erythromycin/Bacitracin ung hs (D)</p> Signup and view all the answers

What is a typical follow-up interval for patients treated for severe staphylococcal infections?

<p>Every 5-7 days (B)</p> Signup and view all the answers

What is the primary treatment for inflamed conditions related to pingueculitis?

<p>FML QID for 5-7 days (D)</p> Signup and view all the answers

Which of the following symptoms is most commonly associated with corneal phlyctenules?

<p>FB sensation (D)</p> Signup and view all the answers

Which statement about the lesions associated with conjunctival phlyctenules is accurate?

<p>They tend to be small white nodules surrounded by a hyperemic response. (A)</p> Signup and view all the answers

Which testing method is primarily used to check for tuberculosis in the context of phlyctenular conjunctivitis?

<p>PPD skin test (A)</p> Signup and view all the answers

What is a potential complication of untreated corneal phlyctenules?

<p>Progression to a gray-white corneal mass (A)</p> Signup and view all the answers

Which demographic is most frequently affected by conjunctival phlyctenules?

<p>Women in the 1st and 2nd decades living in impoverished environments (B)</p> Signup and view all the answers

What underlying condition is commonly associated with the occurrence of phlyctenular conjunctivitis?

<p>HIV (B)</p> Signup and view all the answers

When can lubricants be used for treating non-inflamed conditions?

<p>Every 3 hours - QID (B)</p> Signup and view all the answers

What does the systemic treatment typically involve for managing oral lesions?

<p>Oral mouthwash and topical steroids (B)</p> Signup and view all the answers

Which of the following ocular conditions is characterized by the presence of a membrane on the conjunctiva?

<p>Pseudomembrane conjunctivitis (B)</p> Signup and view all the answers

How should abrasions typically be treated?

<p>Using antibiotic ointment and frequent follow-up (A)</p> Signup and view all the answers

What is an appropriate initial management step for ocular dry eye conditions?

<p>Non-preserved lubricants (B)</p> Signup and view all the answers

Which treatment is indicated for lacerations that are greater than 1-1.5 cm?

<p>Referral for suturing (A)</p> Signup and view all the answers

What is the primary treatment approach for hemolytic anemia?

<p>Immunosuppressants with oral steroids (C)</p> Signup and view all the answers

Which of the following factors can precipitate Steven’s-Johnson Syndrome?

<p>Mycoplasma pneumoniae (D)</p> Signup and view all the answers

Which feature is characteristic of the primary lesions in Steven’s-Johnson Syndrome?

<p>Target lesions with red centers (B)</p> Signup and view all the answers

What is the recommended follow-up interval for ocular treatments in patients with hemolytic anemia?

<p>Every few days to weeks (A)</p> Signup and view all the answers

Which treatment is suggested for patients experiencing lid margin disease?

<p>Punctal occlusion (A)</p> Signup and view all the answers

In which demographic is Steven’s-Johnson Syndrome most commonly observed?

<p>Young, healthy individuals aged 3-4 decades (D)</p> Signup and view all the answers

What type of ocular treatment is used for trichiasis or entropion/ectropion?

<p>Bandage contact lenses (B)</p> Signup and view all the answers

What are the common early symptoms of Steven’s-Johnson Syndrome?

<p>Malaise, fever, and headaches (B)</p> Signup and view all the answers

What type of lubricant is recommended for ocular care in patients with specific conditions?

<p>Preservative-free lubricants (D)</p> Signup and view all the answers

What skin condition is characterized by erosive mucocutaneous lesions?

<p>Steven’s-Johnson Syndrome (D)</p> Signup and view all the answers

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Study Notes

Treatment Overview

  • Non-inflamed conditions treated with lubricants every 3 hours (QID) with follow-ups as needed.
  • Inflamed conditions require lubricants every 3 hours (QID) and FML (fluorometholone) drops QID for 5-7 days with follow-ups every 3-7 days.

Pingueculitis

  • Degeneration of the conjunctiva often presenting as redness and irritation.
  • Associated with phlyctenular conjunctivitis, an immune reaction linked to staphylococcal proteins and tuberculosis, common in autoimmune diseases like Behcet’s and HIV.
  • Distinguishes between conjunctival and corneal phlyctenules.
  • Symptoms include foreign body sensation and burning, more prominent with limbal/corneal phlyctenules.

Diagnostic Tests for Phlyctenular Conjunctivitis

  • Tuberculosis assessed via PPD and Chest X-ray.
  • HLA-B51 testing for Behcet’s.
  • HIV screening as needed.

Treatment for Phlyctenular Conjunctivitis

  • Topical steroids to be tapered after initial treatment.
  • If staphylococcal involvement is found, combination treatments including antibiotics may be necessary.
  • Severe cases may require oral doxycycline, tetracycline, or erythromycin.

Superior Limbic Keratoconjunctivitis (SLK)

  • Chronic inflammatory condition affecting the superior bulbar conjunctiva.
  • Primarily affects middle-aged women (aged 20-55), often associated with thyroid disease.
  • Common signs include irritation and inflammation; symptoms can resolve with time.

Management of SLK

  • Treatment focuses on reassurance and lubricants.
  • Avoid NSAIDs and aspirin; regular follow-ups are recommended.
  • Advanced cases may require referrals for underlying conditions.

Mucous Membrane Disorders

  • Includes diseases like ocular cicatricial pemphigoid (OCP) and erythema multiforme.
  • Immune-mediated reactions affecting the mucosal basement membrane.

Ocular Cicatrical Pemphygoid (OCP)

  • Rare disease (incidence of 1 in 15,000-40,000).
  • Typically presents in older adults (after age 55).
  • Blister formation and scarring in the eye can lead to vision loss, with stages of progression noted.

Systemic and Ocular Treatment for OCP

  • Requires a multidisciplinary approach involving internists and dermatologists.
  • Treatment typically includes systemic steroids and immunosuppressants.
  • Ocular management includes lubricants, punctal occlusion, and potential surgery for eyelid deformities.

Stevens-Johnson Syndrome

  • Severe inflammatory condition causing erosive lesions in skin and mucous membranes, typically triggered by medications or infections.
  • Symptoms include fever, malaise, and distinctive target lesions.
  • Requires hospitalization and elimination of potential causes with extensive ocular treatment for complications.

Abrasions and Lacerations

  • Abrasions show localized staining with NaFl; treatment includes topical antibiotics without the need for patching.
  • Lacerations can reveal a loose conjunctival flap; management involves evaluation and possible suturing for larger lacerations.
  • Follow-up for both conditions occurs in a range of 3-7 days depending on severity.

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