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Questions and Answers
What is the mechanism of action of erythromycin?
What is the mechanism of action of erythromycin?
Binds to 50s ribosomal subunit resulting in blockage of transpeptidation
What is the therapeutic category of erythromycin?
What is the therapeutic category of erythromycin?
Antibiotic ophthalmic
For what indications would erythromycin be utilized? (Select all that apply)
For what indications would erythromycin be utilized? (Select all that apply)
What are the precautions for using erythromycin?
What are the precautions for using erythromycin?
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What are some adverse reactions related to erythromycin? (Select all that apply)
What are some adverse reactions related to erythromycin? (Select all that apply)
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How may erythromycin affect drug interactions?
How may erythromycin affect drug interactions?
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How is erythromycin administered?
How is erythromycin administered?
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What nursing implications are relevant when administering erythromycin? (Select all that apply)
What nursing implications are relevant when administering erythromycin? (Select all that apply)
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What patient teaching is necessary related to erythromycin?
What patient teaching is necessary related to erythromycin?
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What key points should be included when administering erythromycin to an infant?
What key points should be included when administering erythromycin to an infant?
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Erythromycin ointment is __________ and __________.
Erythromycin ointment is __________ and __________.
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Study Notes
Mechanism of Action
- Erythromycin binds to the 50S ribosomal subunit, inhibiting transpeptidation during protein synthesis.
Therapeutic Category
- Classified as an antibiotic specifically for ophthalmic use.
Indications
- Treats ocular infections effectively.
- Prophylactic use for ophthalmia neonatorum caused by Neisseria gonorrhoeae or Chlamydia trachomatis.
Warnings and Precautions
- Intended for ophthalmic use only.
- Avoid contact between the applicator tip and the eye to prevent contamination.
Adverse Reactions
- Possible hypersensitivity reactions.
- Minor ocular irritation and redness may occur.
- Can cause chemical conjunctivitis lasting 24-48 hours and temporary blurred vision.
Drug Interactions
- Erythromycin may elevate levels of vitamin K antagonists like warfarin.
Administration Guidelines
- Administered ophthalmically; store between 68°F and 77°F.
Nursing Implications
- Pregnancy risk factor is categorized as B with no adverse effects noted in animal studies.
- Caution is advised when administering to nursing mothers, recommending administration within the first 1-2 hours after birth.
Patient Education
- Patients should be informed about possible eye redness after administration.
- Immediate reporting of any vision changes, eye pain, or severe irritation to a prescriber is crucial.
Prophylactic Use
- Erythromycin ointment is both bacteriostatic and bactericidal.
- Essential for preventing ophthalmia neonatorum in newborns of infected mothers.
Application Technique
- A 1-2 cm ribbon of ointment is applied to the lower conjunctival sac of each eye or delivered in drop form.
Bonding Concerns
- If administering to an infant, reassurances can be given that the medication can be delayed until after the first breastfeeding, allowing for bonding without significant interference.
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Description
This quiz covers the mechanism of action, therapeutic category, and administration guidelines for ophthalmic erythromycin. It also includes information on indications, warnings, adverse reactions, and nursing implications. Test your knowledge on this important antibiotic used in ocular infections.
