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Questions and Answers
What is the purpose of the fusion method described in the text?
What is the purpose of the fusion method described in the text?
- To subject all components to the lowest temperature possible
- To add additional substances at the highest temperature possible
- To minimize subjecting all components to the highest temperature (correct)
- To produce a melt at the highest temperature possible
What must ointments and other semisolid dosage forms meet according to USP tests?
What must ointments and other semisolid dosage forms meet according to USP tests?
- Chemical composition requirements
- Microbial content standards (correct)
- Minimum viscosity standards
- Physical appearance guidelines
Why are topical preparations not required to be sterile?
Why are topical preparations not required to be sterile?
- They are naturally resistant to microbial growth
- They are not intended for internal use (correct)
- They do not contain any water
- They are always used in combination with preservatives
What must dermatological products be examined for in terms of microbial content?
What must dermatological products be examined for in terms of microbial content?
What are ointments, creams, and gels primarily intended for?
What are ointments, creams, and gels primarily intended for?
When using topical products, what should be considered in pregnant or nursing patients?
When using topical products, what should be considered in pregnant or nursing patients?
What is the purpose of an ophthalmic ointment?
What is the purpose of an ophthalmic ointment?
In what ways can semisolid dosage forms like ointments, creams, and gels be used?
In what ways can semisolid dosage forms like ointments, creams, and gels be used?
What is the most favorable advantage of emulgel?
What is the most favorable advantage of emulgel?
Which substance is used as a gelling agent in MetroGel?
Which substance is used as a gelling agent in MetroGel?
What does the term 'emulgel' refer to?
What does the term 'emulgel' refer to?
What are the components that gels may be formulated to contain, in addition to the gelling agent and water?
What are the components that gels may be formulated to contain, in addition to the gelling agent and water?
Why is ocular ophthalmic drug penetration limited?
Why is ocular ophthalmic drug penetration limited?
How is the residence time of ophthalmic ointments compared to ophthalmic solutions?
How is the residence time of ophthalmic ointments compared to ophthalmic solutions?
What standards must ophthalmic ointments meet in addition to quality standards for ointments?
What standards must ophthalmic ointments meet in addition to quality standards for ointments?
How are drugs incorporated into preparing sterile ophthalmic ointments?
How are drugs incorporated into preparing sterile ophthalmic ointments?
What is the emollient effect of oleaginous bases on the skin?
What is the emollient effect of oleaginous bases on the skin?
What is a key advantage of petrolatum (Vaseline) as an oleaginous base for semi-solid dosage forms?
What is a key advantage of petrolatum (Vaseline) as an oleaginous base for semi-solid dosage forms?
Why is it difficult to incorporate water and aqueous preparations into oleaginous bases?
Why is it difficult to incorporate water and aqueous preparations into oleaginous bases?
What is the primary reason for using oleaginous bases in semi-solid dosage forms?
What is the primary reason for using oleaginous bases in semi-solid dosage forms?
What is the primary factor to consider when selecting an ointment base for drug formulation?
What is the primary factor to consider when selecting an ointment base for drug formulation?
How are ointments primarily prepared when considering the nature of the ingredients?
How are ointments primarily prepared when considering the nature of the ingredients?
What characteristic differentiates ointments from creams in their application?
What characteristic differentiates ointments from creams in their application?
What property allows ointments to be effectively washed with water?
What property allows ointments to be effectively washed with water?
What is the primary difference between white ointment and yellow ointment, USP?
What is the primary difference between white ointment and yellow ointment, USP?
What is the function of absorption bases like Hydrophilic petrolatum and lanolin?
What is the function of absorption bases like Hydrophilic petrolatum and lanolin?
What is White petrolatum, USP, primarily composed of?
What is White petrolatum, USP, primarily composed of?
Why are absorption bases like Hydrophilic petrolatum and lanolin not easily removed from the skin by water washing?
Why are absorption bases like Hydrophilic petrolatum and lanolin not easily removed from the skin by water washing?
Why is ocular ophthalmic drug penetration limited?
Why is ocular ophthalmic drug penetration limited?
What additional standards must ophthalmic ointments meet apart from quality standards?
What additional standards must ophthalmic ointments meet apart from quality standards?
How does the residence time of ophthalmic ointments compare to ophthalmic solutions?
How does the residence time of ophthalmic ointments compare to ophthalmic solutions?
Why is special aseptic techniques and processing required for rendering an ophthalmic ointment sterile?
Why is special aseptic techniques and processing required for rendering an ophthalmic ointment sterile?
What is the primary reason for considering systemic drug absorption when using topical products in pregnant or nursing patients?
What is the primary reason for considering systemic drug absorption when using topical products in pregnant or nursing patients?
What is the primary function of absorption bases like Hydrophilic petrolatum and lanolin in semi-solid dosage forms?
What is the primary function of absorption bases like Hydrophilic petrolatum and lanolin in semi-solid dosage forms?
What should be considered when selecting a semisolid base for treating a topical affliction?
What should be considered when selecting a semisolid base for treating a topical affliction?
Which statement best describes the purpose of ophthalmic ointments?
Which statement best describes the purpose of ophthalmic ointments?
What type of containers should be used to store light-sensitive semisolid preparations?
What type of containers should be used to store light-sensitive semisolid preparations?
What is the primary purpose of using a softening point close to body temperature for ophthalmic ointment bases?
What is the primary purpose of using a softening point close to body temperature for ophthalmic ointment bases?
Which substances are commonly used as the base in medicated and non-medicated ophthalmic ointments?
Which substances are commonly used as the base in medicated and non-medicated ophthalmic ointments?
What labeling requirement does the USP direct for certain ointments and creams?
What labeling requirement does the USP direct for certain ointments and creams?
What is a primary advantage of oleaginous bases in semi-solid dosage forms?
What is a primary advantage of oleaginous bases in semi-solid dosage forms?
What is the emullient effect of oleaginous bases on the skin primarily attributed to?
What is the emullient effect of oleaginous bases on the skin primarily attributed to?
Why can water and aqueous preparations be incorporated into oleaginous bases only in small amounts and with some difficulty?
Why can water and aqueous preparations be incorporated into oleaginous bases only in small amounts and with some difficulty?
What is a defining characteristic of petrolatum (Vaseline) as an oleaginous base for semi-solid dosage forms?
What is a defining characteristic of petrolatum (Vaseline) as an oleaginous base for semi-solid dosage forms?
What is the primary reason for the limited penetration of ocular ophthalmic drugs?
What is the primary reason for the limited penetration of ocular ophthalmic drugs?
What is the key advantage of ophthalmic ointments and gels over ophthalmic solutions?
What is the key advantage of ophthalmic ointments and gels over ophthalmic solutions?
Why must ophthalmic ointments meet USP sterility tests in addition to quality standards?
Why must ophthalmic ointments meet USP sterility tests in addition to quality standards?
What is the process required for rendering an ophthalmic ointment sterile?
What is the process required for rendering an ophthalmic ointment sterile?
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