Oncology and Odontogenic Tumors Overview
33 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the other term for Adenomatoid Odontogenic Tumor?

  • Fibromyxoma
  • Adenoameloblastoma (correct)
  • Calcifying Epithelial Odontogenic Tumor
  • Cementoblastoma

Which of these options are considered potential sources of Ameloblastoma?

  • Enamel Organ
  • Odontogenic rest
  • Reduced enamel epithelium
  • Epithelial lining of odontogenic cyst
  • All of the above (correct)

Ameloblastoma, a tumor of the oral cavity, is considered the most aggressive type of tumor in the oral cavity.

True (A)

What is the mean age of patients with Ameloblastoma?

<p>40 years</p> Signup and view all the answers

What is the primary location of an Ameloblastoma?

<p>Mandible</p> Signup and view all the answers

Which of the following is NOT a common clinical presentation of Ameloblastoma?

<p>Sudden onset of facial pain (D)</p> Signup and view all the answers

What are the two main histopathological subtypes of Ameloblastoma?

<p>Follicular and Plexiform (A)</p> Signup and view all the answers

What is the common histological type of Ameloblastoma?

<p>Follicular</p> Signup and view all the answers

The "Fish Net Pattern" is a characteristic feature of the Plexiform Ameloblastoma.

<p>True (A)</p> Signup and view all the answers

What is the usual radiographic appearance of a Peripheral Ameloblastoma?

<p>All of the above (D)</p> Signup and view all the answers

Conservative treatment is typically preferred for peripheral ameloblastoma.

<p>True (A)</p> Signup and view all the answers

What is the treatment of choice for large or aggressive Ameloblastoma?

<p>Surgical excision</p> Signup and view all the answers

Radiotherapy is a commonly used treatment for Ameloblastoma due to its effectiveness.

<p>False (B)</p> Signup and view all the answers

What is the recurrence rate of ameloblastoma after curettage?

<p>50-90% (B)</p> Signup and view all the answers

What is another term for Calcifying Epithelial Odontogenic Tumor?

<p>Pindborg Tumor</p> Signup and view all the answers

Where is Calcifying Epithelial Odontogenic Tumor (CEOT) primarily located?

<p>Mandible (A)</p> Signup and view all the answers

What is the typical radiographic appearance of CEOT (Calcifying Epithelial Odontogenic Tumor)?

<p>Multilocular often causing cortical expansion</p> Signup and view all the answers

Which of the following is NOT a differential diagnosis for CEOT?

<p>Ameloblastoma (C)</p> Signup and view all the answers

Treatment is always required for CEOT.

<p>False (B)</p> Signup and view all the answers

What is another term for Periapical Cementoosseous Dysplasia?

<p>Cementoma (A)</p> Signup and view all the answers

What is the primary location of Periapical Cementoosseous Dysplasia?

<p>Mandible, anterior periapical region</p> Signup and view all the answers

Periapical Cementoosseous Dysplasia most commonly affects males.

<p>False (B)</p> Signup and view all the answers

What is the typical radiographic pattern of Cementoameloblastoma?

<p>Opaque lesion replacing the root of the tooth (D)</p> Signup and view all the answers

Cementoameloblastoma is a malignant tumor.

<p>False (B)</p> Signup and view all the answers

What is the standard treatment for Cementoameloblastoma?

<p>Extraction of the tooth</p> Signup and view all the answers

Clear Cell Odontogenic Tumor is a common neoplasm of the mandible and maxilla.

<p>False (B)</p> Signup and view all the answers

Which of the following is a common feature of Clear Cell Odontogenic Tumor?

<p>Local aggression (D)</p> Signup and view all the answers

Clear Cell Odontogenic Tumor frequently metastasizes to other organs.

<p>False (B)</p> Signup and view all the answers

Odontogenic Myxoma is a benign neoplasm.

<p>True (A)</p> Signup and view all the answers

Which of the following accurately describes the radiographic appearance of Odontogenic Myxoma?

<p>Multilocular, often with a honeycombed appearance (B)</p> Signup and view all the answers

Central Odontogenic Fibroma primarily affects the maxilla.

<p>False (B)</p> Signup and view all the answers

The treatment of choice for Central Odontogenic Fibroma is surgical excision.

<p>True (A)</p> Signup and view all the answers

The prognosis for Central Odontogenic Fibroma is generally poor.

<p>False (B)</p> Signup and view all the answers

Flashcards

What is an ameloblastoma?

A benign, aggressive tumor that originates from the dental lamina or dental organ. It is the most aggressive tumor of the oral cavity.

What is ameloblastic carcinoma?

A malignant tumor that originates from the enamel organ, odontogenic rests, or reduced enamel epithelium. It is characterized by aggressive growth and invasion.

What is an adenomatoid odontogenic tumor?

A benign tumor that contains ductlike or glandlike structures. It is associated with impacted teeth, especially in the anterior maxilla.

What is a clear cell odontogenic tumor?

A rare tumor of the mandible and maxilla that is composed of clear cells. It is known for its locally aggressive nature and potential for metastasis.

Signup and view all the flashcards

What is an odontogenic myxoma?

A benign tumor derived from the mesenchymal tissue of the dental pulp. It is characterized by myxomatous connective tissue and a honeycombed radiographic appearance.

Signup and view all the flashcards

What is a central odontogenic fibroma?

A benign tumor that originates from the mesenchymal part of the dental follicle. It is characterized by mature fibrous tissue and sometimes calcific deposits.

Signup and view all the flashcards

What is periapical cementoosseous dysplasia?

A reactive process, not a tumor, that involves periapical bone and cementum. It is most commonly found in the anterior mandible and affects multiple teeth.

Signup and view all the flashcards

What is a cementoblastoma?

A rare benign tumor originating from cementoblasts. It is characterized by a dense mass of cementum-like material that clings to the tooth root.

Signup and view all the flashcards

What is a peripheral ameloblastoma?

A type of ameloblastoma that occurs in the peripheral gingiva, often in older patients. It is typically less aggressive and has a low recurrence rate.

Signup and view all the flashcards

What is a desmoplastic ameloblastoma?

A type of ameloblastoma that is characterized by a desmoplastic stroma and squamoid or elongated tumor islands. It is less common than other ameloblastoma subtypes.

Signup and view all the flashcards

What is a basal cell ameloblastoma?

A type of ameloblastoma that is characterized by a basaloid epithelial pattern, resembling basal cell carcinoma.

Signup and view all the flashcards

What is a granular cell ameloblastoma?

A type of ameloblastoma that is characterized by central neoplastic cells with prominent cytoplasmic granularity. It is a rare variant.

Signup and view all the flashcards

What is a cystic ameloblastoma?

A type of ameloblastoma that is characterized by multicystic lesions and cortical perforation. It has a high recurrence rate and occurs in younger individuals.

Signup and view all the flashcards

What is a unicystic ameloblastoma?

A type of ameloblastoma that is characterized by a single cyst with specific features, differentiating it from other cystic lesions.

Signup and view all the flashcards

What is ameloblastic carcinoma?

A rare variant of ameloblastoma that is characterized by features of both ameloblastoma and squamous cell carcinoma. It has a more aggressive course.

Signup and view all the flashcards

What is another name for Pindborg tumor?

A synonym for calcifying epithelial odontogenic tumor (CEOT).

Signup and view all the flashcards

What is a clear cell variant of CEOT?

A type of calcifying epithelial odontogenic tumor (CEOT) characterized by clear cells, which are cells with a clear cytoplasm. It is a rare variant of CEOT but has similar features.

Signup and view all the flashcards

What are Liesegang rings?

Concentric calcific deposits that are often seen in calcifying epithelial odontogenic tumor (CEOT). They are thought to be calcified amyloid or amyloid-like material.

Signup and view all the flashcards

What is cherubism?

A condition characterized by bilateral jaw expansion due to fibrous dysplasia, often involving the maxilla.

Signup and view all the flashcards

What is an adenomatoid odontogenic tumor (AOT)?

A benign tumor that occurs most commonly in the anterior maxilla, usually associated with impacted teeth.

Signup and view all the flashcards

What is a sinonasal ameloblastoma?

A rare type of ameloblastoma that occurs in the nasal cavity and sinuses. It is associated with nasal obstruction, epistaxis, and opacification of the sinuses.

Signup and view all the flashcards

What is a honeycomb pattern in radiographs?

The radiographic pattern often seen in odontogenic myxomas, characterized by multiple compartments separated by straight septa forming squares, rectangles, and triangles.

Signup and view all the flashcards

What is jaw expansion?

A clinical feature of some tumors, including ameloblastoma, characterized by painless expansion of the jaw bone. This can be discovered during routine radiographic examinations.

Signup and view all the flashcards

What is an odontogenic myxoma?

A type of odontogenic tumor that microscopically resembles the dental pulp or follicular connective tissue, and is often associated with both the maxilla and mandible.

Signup and view all the flashcards

What is a dentigerous cyst?

A condition where the crown of an impacted tooth is enveloped within a cyst. It is significant to consider in differential diagnoses of odontogenic tumors.

Signup and view all the flashcards

What is surgical excision?

A treatment approach for odontogenic tumors, involving the complete removal of the affected area.

Signup and view all the flashcards

What is conservative treatment?

A treatment method for odontogenic tumors that involves removal of only the affected part of the jaw bone.

Signup and view all the flashcards

Study Notes

Oncology Definition

  • Study of inflammatory growths like cells, neutrophils, and lymphocytes
  • Deals with diseases like tumors and cancers

Odontogenic Tumors

  • Originate from dental organs or dental lamina
  • Types:
    • Epithelial Odontogenic Tumor
    • Mesenchymal Odontogenic Tumor
    • Mixed Odontogenic Tumor

Ameloblastoma

  • Aggressive oral cavity tumor
  • Originates from epithelium that forms teeth
  • Possible sources: enamel organ, dental rests (rests of Malassez, rests of Serres), reduced enamel epithelium (REE), epithelial lining of odontogenic cysts (especially dentigerous cysts)
  • Mechanism for gaining growth advantage:
    • overexpression of TNF-α
    • interface proteins (FGF)
    • anti-apoptotic proteins (Bcl-2, Bcl-x1)
    • matrix metalloproteinases (MMPs)
  • Location: mandible and maxilla

Clinical Features of Ameloblastoma

  • Usually asymptomatic
  • Often discovered during routine radiographic exams
  • Possible signs: jaw expansion, movement or malocclusion of teeth

Biological Subtypes of Ameloblastoma

  • Peripheral (extraosseous):
    • May occur in gingiva or buccal mucosa
    • More common in older patients (40-60 years of age)
    • May arise from rests of Serres
    • Less likely to recur

Cystic Ameloblastoma

  • Formerly known as unicystic ameloblastoma
  • High recurrence rate (40%)
  • Common in younger patients (mean age 35)
  • May exhibit cortical perforation
  • Should be differentiated from reactive epithelial changes in radicular cysts

Malignant Variants

  • Relatively common in younger patients (30 years)
  • Can metastasize to local lymph nodes or distant organs

Malignant Ameloblastoma

  • Microscopically well-differentiated primary and metastatic lesions

Ameloblastic Carcinoma

  • Microscopically less-differentiated primary and metastatic lesions
  • Characterized by marked nuclear atypia and numerous mitotic figures

Sinonasal Ameloblastoma

  • Mean age: 61
  • Predominantly affects males
  • Symptoms include nasal obstruction and epistaxis (nosebleeds)

Other Odontogenic Tumors

Detailed information on other odontogenic tumor subtypes is covered in subsequent pages, including their specific clinical features, radiographic appearances, histology, and treatment.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Related Documents

ONCOLOGY Past Paper PDF

Description

This quiz covers key concepts in oncology, focusing on inflammatory growths such as tumors and cancers. It provides detailed insights into odontogenic tumors like ameloblastoma, including their origins, clinical features, and mechanisms of growth. Test your understanding of these important topics in dental pathology.

More Like This

Odontogenic Tumors and Ameloblastoma
26 questions

Odontogenic Tumors and Ameloblastoma

GodGivenEpic avatar
GodGivenEpic
Odontogenic Tumors: Ameloblastoma
6 questions

Odontogenic Tumors: Ameloblastoma

GenerousAmaranth avatar
GenerousAmaranth
Odontogenic Tumors and Ameloblastoma
20 questions

Odontogenic Tumors and Ameloblastoma

FeasibleAstronomy9210 avatar
FeasibleAstronomy9210
Use Quizgecko on...
Browser
Open
Browser
Browser