Oncogenic Viruses and Bacterial Carcinogens
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Questions and Answers

Which oncogenic virus is primarily associated with Kaposi sarcoma?

  • Herpes virus (HHV8) (correct)
  • Hepatitis B virus (HBV)
  • Human T-cell leukemia virus (HTLV-1)
  • Human papilloma virus (HPV)

What type of cancer is most commonly associated with Epstein-Barr virus (EBV)?

  • Adult T-cell leukemia
  • Hepatocellular carcinoma
  • Burkitt lymphoma (correct)
  • Cervical carcinoma

Which of the following viruses is known to cause squamous cell carcinomas primarily in the cervix?

  • Human T-cell leukemia virus (HTLV-1)
  • Helicobacter pylori
  • Hepatitis C virus (HCV)
  • Human papilloma virus (HPV) (correct)

Which virus is linked to the progression from liver cirrhosis to hepatocellular carcinoma?

<p>Hepatitis B virus (HBV) (D)</p> Signup and view all the answers

Which of the following is a bacterial carcinogen associated with gastric adenocarcinoma?

<p>Helicobacter pylori (A)</p> Signup and view all the answers

Flashcards

Oncogenic Viruses

Viruses that can cause cancer.

HTLV-1

A type of RNA virus that causes adult T-cell leukemia/lymphoma.

EBV

A DNA virus linked to various cancers, including Burkitt's lymphoma and nasopharyngeal carcinoma.

HBV/HCV

These viruses can lead to liver cancer (hepatocellular carcinoma) after causing cirrhosis.

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HPV

A DNA virus responsible for cervical cancer and other squamous cell carcinomas.

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Study Notes

Oncogenic Viruses

  • Some viruses contribute to cancer development.
  • RNA viruses associated with cancer include Human T-cell leukemia virus (HTLV-1), which causes adult T-cell leukemia/lymphoma.
  • DNA viruses linked to cancer include Epstein-Barr virus (EBV). EBV is associated with Burkitt lymphoma, Hodgkin lymphoma, nasopharyngeal and gastric carcinomas, and primary CNS lymphoma in immunocompromised individuals.
  • Hepatitis B and C viruses (HBV and HCV) are linked to hepatocellular carcinoma, a liver cancer arising from cirrhosis.
  • Human papillomavirus (HPV) causes benign squamous papillomas (warts) and squamous cell carcinomas, predominantly in the cervix but also in the vulva, vagina, penis, anus, and oral cavity.
  • Herpes virus type 8 (HHV8) is associated with Kaposi sarcoma.

Bacterial Carcinogens

  • Helicobacter pylori is a bacteria linked to gastric adenocarcinoma and gastric lymphomas (MALT).

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Description

This quiz explores the role of oncogenic viruses and bacterial carcinogens in cancer development. It covers various RNA and DNA viruses linked to specific cancers, including HTLV-1, EBV, HPV, and others, as well as the impact of Helicobacter pylori. Test your knowledge on how these pathogens contribute to different forms of cancer.

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