Oncogenic Viruses and Bacterial Carcinogens

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Questions and Answers

Which virus is primarily associated with causing adult T-cell leukemia/lymphoma?

  • Hepatitis B virus (HBV)
  • Human papilloma virus (HPV)
  • Human T-cell leukemia virus (HTLV-1) (correct)
  • Epstein-Barr virus (EBV)

Which of the following viruses is linked to hepatocellular carcinoma?

  • Human papilloma virus (HPV)
  • Epstein-Barr virus (EBV)
  • Hepatitis B and C viruses (HBV + HCV) (correct)
  • Herpes virus (HHV8)

What type of cancer is predominantly caused by Human papilloma virus (HPV)?

  • Kaposi sarcoma
  • Gastric adenocarcinoma
  • Burkitt lymphoma
  • Benign squamous papilloma (correct)

Which oncogenic virus is associated with Kaposi sarcoma?

<p>Herpes virus (HHV8) (D)</p> Signup and view all the answers

What type of lymphomas can occur as a result of infection with Helicobacter pylori?

<p>Gastric lymphomas (MALT) (D)</p> Signup and view all the answers

Flashcards

Oncogenic Viruses

Viruses that can cause cancer.

HTLV-1

A type of RNA virus causing leukemia.

EBV

A DNA virus linked to several cancers, especially in immunocompromised people.

HPV

A DNA virus linked to cervical cancer and other squamous cell cancers.

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Helicobacter pylori

A bacteria causing stomach cancer and lymphomas.

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Study Notes

Oncogenic Viruses

  • Certain viruses are linked to cancer development.
  • RNA viruses associated with cancer include:
    • Human T-cell leukemia virus (HTLV-1) causing adult T-cell leukemia/lymphoma.
  • DNA viruses linked to cancer include:
    • Epstein-Barr virus (EBV) causing Burkitt lymphoma, Hodgkin lymphoma, nasopharyngeal and gastric carcinomas, and primary central nervous system lymphoma (in immunocompromised).
    • Hepatitis B and C viruses (HBV and HCV) causing hepatocellular carcinoma, starting from liver cirrhosis.
    • Human papillomavirus (HPV) causing benign squamous papillomas (warts) and squamous cell carcinomas, primarily in the cervix but also in the vulva, vagina, penis, anus, and oral cavity.
    • Herpes virus (HHV8) causing Kaposi sarcoma.

Bacterial Carcinogens

  • Some bacteria can also contribute to cancer.
  • Helicobacter pylori causes gastric adenocarcinoma and gastric lymphomas (MALT).

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