Oncofetal Antigens in Cancer Detection
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Questions and Answers

Which of the following tumor markers is specifically associated with the follow-up of colorectal carcinoma?

  • Carcinoembryonic Antigen (CEA) (correct)
  • Human Chorionic Gonadotropin (HCG)
  • α1-Fetoprotein (AFP)
  • Placental-like ALP
  • What tumor marker is used for the early diagnosis, detection of CNS metastasis, and follow-up of trophoblastic tissue tumors?

  • Placental-like ALP
  • Human Chorionic Gonadotropin (HCG) (correct)
  • α1-Fetoprotein (AFP)
  • Carcinoembryonic Antigen (CEA)
  • In addition to Human Chorionic Gonadotropin (HCG), which other tumor marker is used for the follow-up of malignant teratoma?

  • α1-Fetoprotein (AFP) (correct)
  • Carcinoembryonic Antigen (CEA)
  • Placental-like ALP
  • None of the above
  • Which tumor marker is specifically monitored in patients treated for seminoma?

    <p>Placental-like ALP</p> Signup and view all the answers

    For the early detection and follow-up of hepatoma, which specific form of AFP is measured?

    <p>Fucosylated AFP</p> Signup and view all the answers

    Study Notes

    Oncofetal Antigens

    • Produced mainly by normal cells of fetus or placenta, leading to higher levels in mothers and babies compared to healthy adults.
    • Production increases in certain tumors in adults.

    Tumor Markers

    • α1-Fetoprotein (AFP)
      • Used for follow-up of malignant teratoma in conjunction with HCG.
      • Used for early detection and follow-up of hepatoma by measuring fucosylated AFP.

    Tumor Markers

    • Carcinoembryonic Antigen (CEA)
      • Used for follow-up of colorectal carcinoma.

    Tumor Markers

    • Human Chorionic Gonadotropin (HCG)
      • Used for early diagnosis, detection of CNS metastasis, and follow-up of trophoblastic tissue tumors.
      • Used for follow-up of teratoma in conjunction with AFP, specifically for testicular teratoma.

    Tumor Markers

    • Placental-like ALP
      • Used for monitoring patients treated for seminoma.

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    Description

    Learn about oncofetal antigens, produced by fetus or placenta, and their increased levels in certain tumors, used as tumor markers for cancer detection and follow-up.

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