Oncofetal Antigens in Cancer Detection

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5 Questions

Which of the following tumor markers is specifically associated with the follow-up of colorectal carcinoma?

Carcinoembryonic Antigen (CEA)

What tumor marker is used for the early diagnosis, detection of CNS metastasis, and follow-up of trophoblastic tissue tumors?

Human Chorionic Gonadotropin (HCG)

In addition to Human Chorionic Gonadotropin (HCG), which other tumor marker is used for the follow-up of malignant teratoma?

α1-Fetoprotein (AFP)

Which tumor marker is specifically monitored in patients treated for seminoma?

Placental-like ALP

For the early detection and follow-up of hepatoma, which specific form of AFP is measured?

Fucosylated AFP

Study Notes

Oncofetal Antigens

  • Produced mainly by normal cells of fetus or placenta, leading to higher levels in mothers and babies compared to healthy adults.
  • Production increases in certain tumors in adults.

Tumor Markers

  • α1-Fetoprotein (AFP)
    • Used for follow-up of malignant teratoma in conjunction with HCG.
    • Used for early detection and follow-up of hepatoma by measuring fucosylated AFP.

Tumor Markers

  • Carcinoembryonic Antigen (CEA)
    • Used for follow-up of colorectal carcinoma.

Tumor Markers

  • Human Chorionic Gonadotropin (HCG)
    • Used for early diagnosis, detection of CNS metastasis, and follow-up of trophoblastic tissue tumors.
    • Used for follow-up of teratoma in conjunction with AFP, specifically for testicular teratoma.

Tumor Markers

  • Placental-like ALP
    • Used for monitoring patients treated for seminoma.

Learn about oncofetal antigens, produced by fetus or placenta, and their increased levels in certain tumors, used as tumor markers for cancer detection and follow-up.

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