Podcast
Questions and Answers
what is the pathophysiology of motor neurone disease
what is the pathophysiology of motor neurone disease
when motor neurones lose their function due to over excitotoxicity, over stimulation from glutamate.
how to treat MND
how to treat MND
riluzole is used to manage the symptoms of MND however their is no cure, riluzole blocks the sodium channels this prevents depolarisation of the pre synaptic neurone, which decreases action potential and decreases the neurotransmission of glutamate.
what are anticholinergic drugs used for CP and their MOA
what are anticholinergic drugs used for CP and their MOA
benzatropine is used for movement regulation and sialorrhoea, it works by blocking ACh from binding to muscarinic receptors. glycopyrrolate is only used for sialorrhoea it is a competitive inhibitor of ACh receptors in peripheral tissues, including salivary glands.
match the following CP muscle relaxant drugs
match the following CP muscle relaxant drugs
dexamfetamine has a ____ duration of action and lisdexamfetamine is a _____.
dexamfetamine has a ____ duration of action and lisdexamfetamine is a _____.
amphetamines MOA is they inhibit dopamine, noradrenaline and serotonin transporters. which increases neurotransmission and improves attention and decreases impulsivness.
amphetamines MOA is they inhibit dopamine, noradrenaline and serotonin transporters. which increases neurotransmission and improves attention and decreases impulsivness.
atomoxetine for ADHD selectively inhibits presynaptic reuptake of noradrenaline in the CNS what are some of the effects.
atomoxetine for ADHD selectively inhibits presynaptic reuptake of noradrenaline in the CNS what are some of the effects.
parkinsons pathophysiology
parkinsons pathophysiology
match the following
match the following
what is he treatment goal for alzheimers disease
what is he treatment goal for alzheimers disease
donepezil, rivastigmine and glantamine are ____ and they decrease breakdown of ACH via binding to and inactivating acetylcholinesterase enzyme. memantine is ____ and it blocks the glutamate receptor via binding to it.
donepezil, rivastigmine and glantamine are ____ and they decrease breakdown of ACH via binding to and inactivating acetylcholinesterase enzyme. memantine is ____ and it blocks the glutamate receptor via binding to it.
what is glutamates role in epilepsy
what is glutamates role in epilepsy
match the following
match the following
MOA of VMAT2 inhibitors such as tetrabenazine
MOA of VMAT2 inhibitors such as tetrabenazine
match the following
match the following
Teriflunomide inhibits pyrimidine synthesis in T cells and B cells
Teriflunomide inhibits pyrimidine synthesis in T cells and B cells
MOA of sphingosine 1-phosphate receptor modulators
MOA of sphingosine 1-phosphate receptor modulators
match the following
match the following
what is the aim of treatment for schizophrenia
what is the aim of treatment for schizophrenia
lithium used for bipolar disorder _____ serotonin synthesis and release whilst ____ dopamine synthesis and release. it also has a ____ therapeutic range also ____ and ____ can decrease lithium excretion.
lithium used for bipolar disorder _____ serotonin synthesis and release whilst ____ dopamine synthesis and release. it also has a ____ therapeutic range also ____ and ____ can decrease lithium excretion.
pathophysiology of migraine
pathophysiology of migraine
what is the MOA of sumatriptan, zolmitriptan and rizatriptan and what are they used for
what is the MOA of sumatriptan, zolmitriptan and rizatriptan and what are they used for
there are two drugs for prophylaxis treatment ____ and ____, _____ works by binding directly to ____ so it cannot bind to its receptor. whereas ____ binds to the ____ receptor blocking ____ from binding.
there are two drugs for prophylaxis treatment ____ and ____, _____ works by binding directly to ____ so it cannot bind to its receptor. whereas ____ binds to the ____ receptor blocking ____ from binding.
drug class, indication and MOA of oxazepam, diazepam, temazepam
drug class, indication and MOA of oxazepam, diazepam, temazepam
difference between z-drugs and benzodiazepines
difference between z-drugs and benzodiazepines
match the following
match the following
adverse effects of combined and progesterone only contraceptives
adverse effects of combined and progesterone only contraceptives
process of acid secretion
process of acid secretion
MOA of proton pump inhibitors such as esomeprazole
MOA of proton pump inhibitors such as esomeprazole
pathophysiology of vomiting
pathophysiology of vomiting
all the laxatives and their MOA
all the laxatives and their MOA
match the following
match the following
describe each of the following drugs MOA, orlistat and phentermine
describe each of the following drugs MOA, orlistat and phentermine
islets of langerhans have ____ cells which produce ____, this promotes glucose release and ___ blood glucose levels. there is also ____ cells, which release ____, this promotes the uptake and gluconeogensis converting glucose to glycogen which ___ blood glucose levels.
islets of langerhans have ____ cells which produce ____, this promotes glucose release and ___ blood glucose levels. there is also ____ cells, which release ____, this promotes the uptake and gluconeogensis converting glucose to glycogen which ___ blood glucose levels.
process of insulin release in normal physiology
process of insulin release in normal physiology
vitamin D as ___ is used to help with the absorption of ___ in the kidney. increased ___ increases bone formation.
vitamin D as ___ is used to help with the absorption of ___ in the kidney. increased ___ increases bone formation.
match the following
match the following
Flashcards
What is the pathophysiology of Motor Neuron Disease (MND)?
What is the pathophysiology of Motor Neuron Disease (MND)?
The process of motor neurons dying due to excessive stimulation by glutamate.
How is MND treated?
How is MND treated?
Riluzole slows down the progression of MND by blocking glutamate release from neurons. It helps manage symptoms but cannot cure the disease.
What is glutamate and its role in MND?
What is glutamate and its role in MND?
A neurotransmitter that plays a crucial role in communication between nerve cells. It can cause damage to neurons when present in high concentrations.
