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Questions and Answers
What is the most common demographic for CEOT occurrences?
What is the most common demographic for CEOT occurrences?
Which area of the jaw is most frequently affected by CEOT?
Which area of the jaw is most frequently affected by CEOT?
What is a characteristic radiographic feature of CEOT?
What is a characteristic radiographic feature of CEOT?
Which of the following is NOT a common histological feature of CEOT?
Which of the following is NOT a common histological feature of CEOT?
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Which condition should be considered in the differential diagnosis if a lesion is pericoronal?
Which condition should be considered in the differential diagnosis if a lesion is pericoronal?
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Which type of odontogenic tumor is characterized as an epithelial-only tumor?
Which type of odontogenic tumor is characterized as an epithelial-only tumor?
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Which statement accurately describes conventional ameloblastoma?
Which statement accurately describes conventional ameloblastoma?
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What is NOT a characteristic radiographic feature of ameloblastoma?
What is NOT a characteristic radiographic feature of ameloblastoma?
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In which age group do ameloblastomas most commonly occur?
In which age group do ameloblastomas most commonly occur?
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Which odontogenic tumor is classified as ectomesenchymal only?
Which odontogenic tumor is classified as ectomesenchymal only?
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Which list correctly identifies odontogenic tumors that are both epithelial and ectomesenchymal?
Which list correctly identifies odontogenic tumors that are both epithelial and ectomesenchymal?
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What common effect might be seen due to the growth of an ameloblastoma?
What common effect might be seen due to the growth of an ameloblastoma?
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How does ameloblastoma typically present radiographically?
How does ameloblastoma typically present radiographically?
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What is the most common histologic pattern observed in ameloblastoma?
What is the most common histologic pattern observed in ameloblastoma?
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Which age group is most commonly affected by unicystic ameloblastoma?
Which age group is most commonly affected by unicystic ameloblastoma?
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What is a common radiographic feature of unicystic ameloblastoma?
What is a common radiographic feature of unicystic ameloblastoma?
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What is the primary treatment for intraosseous ameloblastoma?
What is the primary treatment for intraosseous ameloblastoma?
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What distinguishes extraosseous ameloblastoma from other forms?
What distinguishes extraosseous ameloblastoma from other forms?
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What is the recurrence rate after treatment of extraosseous ameloblastoma?
What is the recurrence rate after treatment of extraosseous ameloblastoma?
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Which feature is characteristic of the histology of unicystic ameloblastoma?
Which feature is characteristic of the histology of unicystic ameloblastoma?
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What common sign may indicate the presence of ameloblastoma?
What common sign may indicate the presence of ameloblastoma?
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What is a common differential diagnosis for unicystic ameloblastoma when pericoronal?
What is a common differential diagnosis for unicystic ameloblastoma when pericoronal?
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What is the prognosis for unicystic ameloblastoma compared to the traditional ameloblastoma?
What is the prognosis for unicystic ameloblastoma compared to the traditional ameloblastoma?
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What is the primary treatment for Ameloblastic Fibroma?
What is the primary treatment for Ameloblastic Fibroma?
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Which type of Odontoma primarily produces small tooth-like structures?
Which type of Odontoma primarily produces small tooth-like structures?
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What is a distinguishing characteristic of Complex Odontoma on radiographic examination?
What is a distinguishing characteristic of Complex Odontoma on radiographic examination?
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During which decades of life do odontomas typically present?
During which decades of life do odontomas typically present?
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Which histological feature is characteristic of Ameloblastic Fibroma?
Which histological feature is characteristic of Ameloblastic Fibroma?
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What is the prognosis for a well-developed odontoma after excision?
What is the prognosis for a well-developed odontoma after excision?
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Which condition can Ameloblastic Fibroma rarely transform into?
Which condition can Ameloblastic Fibroma rarely transform into?
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What type of tissue do odontomas primarily produce?
What type of tissue do odontomas primarily produce?
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What is the primary treatment for cementoblastoma?
What is the primary treatment for cementoblastoma?
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What is a common age range for the occurrence of cementoblastoma?
What is a common age range for the occurrence of cementoblastoma?
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Which feature is NOT characteristic of odontogenic myxoma?
Which feature is NOT characteristic of odontogenic myxoma?
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Which characteristic is associated with primary intraosseous carcinoma of the jaws?
Which characteristic is associated with primary intraosseous carcinoma of the jaws?
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What is the typical location for an ameloblastic fibroma?
What is the typical location for an ameloblastic fibroma?
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Which histologic feature is characteristic of odontogenic myxoma?
Which histologic feature is characteristic of odontogenic myxoma?
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What percentage of cementoblastomas occur in the mandible?
What percentage of cementoblastomas occur in the mandible?
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What's a common radiographic feature of cementoblastoma?
What's a common radiographic feature of cementoblastoma?
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Which of the following best describes the prognosis for odontogenic myxoma?
Which of the following best describes the prognosis for odontogenic myxoma?
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What type of tumor is described as benign and resembling developing tooth microscopically?
What type of tumor is described as benign and resembling developing tooth microscopically?
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What is the most common location for Adenomatoid Odontogenic Tumor (AOT)?
What is the most common location for Adenomatoid Odontogenic Tumor (AOT)?
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What is the defining characteristic that differentiates AOTs from Dentigerous cysts radiographically?
What is the defining characteristic that differentiates AOTs from Dentigerous cysts radiographically?
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Which of the following radiographic features is NOT typically associated with Adenomatoid Odontogenic Tumor (AOT)?
Which of the following radiographic features is NOT typically associated with Adenomatoid Odontogenic Tumor (AOT)?
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Which of the following is NOT a differential diagnosis for Adenomatoid Odontogenic Tumor (AOT) based on radiographic features?
Which of the following is NOT a differential diagnosis for Adenomatoid Odontogenic Tumor (AOT) based on radiographic features?
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What type of cells are characteristically found in the histologic examination of an Adenomatoid Odontogenic Tumor (AOT)?
What type of cells are characteristically found in the histologic examination of an Adenomatoid Odontogenic Tumor (AOT)?
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What is the primary treatment method for Adenomatoid Odontogenic Tumor (AOT)?
What is the primary treatment method for Adenomatoid Odontogenic Tumor (AOT)?
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Which of the following is NOT a characteristic clinical feature of a Primary Intraosseous Carcinoma of the Jaws?
Which of the following is NOT a characteristic clinical feature of a Primary Intraosseous Carcinoma of the Jaws?
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What is the most likely source of a Primary Intraosseous Carcinoma of the Jaws?
What is the most likely source of a Primary Intraosseous Carcinoma of the Jaws?
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Flashcards
CEOT Clinical Features
CEOT Clinical Features
Slow, painless jaw enlargement common in adults, especially in the mandible.
CEOT Radiographic Features
CEOT Radiographic Features
Well-defined unilocular/multilocular lesions typically in the alveolar process.
Cortical Expansion
Cortical Expansion
Common effect of CEOT, leading to bone expansion and root resorption.
Differential Diagnosis
Differential Diagnosis
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Histologic Features of CEOT
Histologic Features of CEOT
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Ameloblastoma
Ameloblastoma
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Histologic Features
Histologic Features
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Unicystic Ameloblastoma
Unicystic Ameloblastoma
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Clinical Features of Unicystic Ameloblastoma
Clinical Features of Unicystic Ameloblastoma
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Radiographic Features
Radiographic Features
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Treatment for Unicystic Ameloblastoma
Treatment for Unicystic Ameloblastoma
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Extraosseous Ameloblastoma
Extraosseous Ameloblastoma
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Clinical Features of Extraosseous Ameloblastoma
Clinical Features of Extraosseous Ameloblastoma
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Differential Diagnosis of Extraosseous Ameloblastoma
Differential Diagnosis of Extraosseous Ameloblastoma
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Calcifying Epithelial Odontogenic Tumor (CEOT)
Calcifying Epithelial Odontogenic Tumor (CEOT)
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Odontogenic Tumors
Odontogenic Tumors
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Types of Ameloblastoma
Types of Ameloblastoma
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Conventional Ameloblastoma
Conventional Ameloblastoma
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Radiographic Features of Ameloblastoma
Radiographic Features of Ameloblastoma
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Common Effects of Ameloblastoma
Common Effects of Ameloblastoma
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Epithelial Only Odontogenic Tumors
Epithelial Only Odontogenic Tumors
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Mixed Odontogenic Tumors
Mixed Odontogenic Tumors
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Liesegang rings
Liesegang rings
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Congo red stain
Congo red stain
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Amyloid-like material
Amyloid-like material
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Adenomatoid Odontogenic Tumor (AOT)
Adenomatoid Odontogenic Tumor (AOT)
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AOT demographic
AOT demographic
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Differential diagnosis for AOT
Differential diagnosis for AOT
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Primary Intraosseous Carcinoma
Primary Intraosseous Carcinoma
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5-year survival rate
5-year survival rate
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Cementoblastoma
Cementoblastoma
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Cementoblastoma symptoms
Cementoblastoma symptoms
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Cementoblastoma radiographic features
Cementoblastoma radiographic features
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Cementoblastoma treatment
Cementoblastoma treatment
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Odontogenic Myxoma
Odontogenic Myxoma
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Odontogenic Myxoma symptoms
Odontogenic Myxoma symptoms
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Histologic features of Odontogenic Myxoma
Histologic features of Odontogenic Myxoma
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Ameloblastic Fibroma
Ameloblastic Fibroma
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Differential Diagnosis: Ameloblastic Fibroma
Differential Diagnosis: Ameloblastic Fibroma
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Histologic Features: Ameloblastic Fibroma
Histologic Features: Ameloblastic Fibroma
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Treatment: Ameloblastic Fibroma
Treatment: Ameloblastic Fibroma
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Odontoma
Odontoma
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Clinical Features: Odontoma
Clinical Features: Odontoma
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Odontoma Types: Compound vs Complex
Odontoma Types: Compound vs Complex
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Prognosis: Odontoma
Prognosis: Odontoma
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Study Notes
Odontogenic Tumors
- Odontogenic tumors are tumors arising from tissues associated with teeth.
Odontogenic Epithelium and Ectomesenchyme
- Outer enamel epithelium, stellate reticulum, stratum intermedium, inner enamel epithelium, dental papilla, and dental follicle are crucial components involved in tooth development.
- These structures are crucial for understanding odontogenic tumors' origins.
Tissue of Origin
- Epithelial only: Ameloblastoma, CEOT (Calcifying epithelial odontogenic tumor), AOT (Adenomatoid odontogenic tumor).
- Ectomesenchymal only: Cementoblastoma, Odontogenic myxoma.
- Epithelial and ectomesenchymal: Ameloblastic fibroma, Odontoma.
- Primary intraosseous carcinoma of the jaws are also included in the classifications of odontogenic tumors.
Ameloblastoma
- Benign tumor with persistent and aggressive growth.
- Originates from the enamel organ.
- 2022 WHO Classification: Conventional ameloblastoma, Unicystic ameloblastoma, Extraosseous/peripheral ameloblastoma.
Conventional Ameloblastoma: Clinical Features
- Accounts for about 80% of ameloblastomas.
- Most commonly present in the 4th and 5th decades.
- Found mostly in the mandible's posterior body and ramus, affecting 85% of cases.
- Characterized by slow, painless expansion in the buccal/lingual dimension.
Ameloblastoma: Radiographic Features
- Solitary lesion, usually arising in the alveolar process, but sometimes pericoronal.
- Radiographic appearance: well-defined, corticated, and irregular radiolucency, ranging from 1 to 10 cm or larger.
- Often unilocular, especially in smaller lesions, or multilocular with coarse trabeculae.
- Irregular outline expanding and eventually resorbing the cortex.
- Tooth displacement and root resorption are common.
Unicystic Ameloblastoma
- Accounts for approximately 15% of ameloblastomas.
- Develops from odontogenic cyst epithelium, or de novo as a neoplasm.
- Usually a cystic lesion appearing in the second or third decade (younger than conventional ameloblastoma).
- Occurs predominantly in the mandible, usually posterior.
- Typically asymptomatic, but large lesions can cause jaw expansion.
- Often pericoronal, well-defined, corticated, round or oval radiolucency, typically unilocular.
- May cause tooth displacement, root resorption, and cortical resorption.
Extraosseous/Peripheral Ameloblastoma
- Accounts for about 1% of all ameloblastomas.
- Originates from odontogenic epithelial rests in the gingiva, or occasionally from basal cells of surface epithelium.
- Mostly found in middle-aged adults (average age 52).
- Characterized by a painless, sessile, or pedunculated mass on the gingiva, most commonly found in the posterior mandible.
Calcifying Epithelial Odontogenic Tumor (CEOT)
- Benign odontogenic tumor that resembles ameloblastoma clinically and radiographically.
- Originates from the enamel organ.
- Commonly found in adults during the 4th and 5th decades, with the majority (75%) in the mandible, specifically the molar-ramus area.
- Characterized by slow, painless enlargement of the jaw, often evident as a prominent buccal-lingual expansion.
- Radiographic appearance: solitary lesion in the alveolar process (50% pericoronal), well-defined, unilocular or multilocular lesion, frequently corticated.
- May exhibit radiolucent areas alone, or radiolucent areas with radiopaque foci that may cluster near the crown of a pericoronal lesion.
- Common general effects include cortical expansion and resorption, with root resorption and displacement.
- Exhibit "Driven snow" pattern in radiographic imaging.
- Histological features include sheets of large, polygonal eosinophilic cells; pleomorphic cells with large nuclei (but benign); and concentric calcifications (Liesegang rings).
- Amyloid-like material is often present, staining with Congo red and thioflavin T.
- Treatment involves conservative excision, which is often effective. Has better prognosis than ameloblastoma.
Adenomatoid Odontogenic Tumor (AOT)
- Benign odontogenic tumor of epithelial origin, arising from the enamel organ.
- Epithelial cells form patterns resembling glandular tumors.uu
- Primarily in the first and second decades, exceedingly rare after 30.
- Predominantly found in females (2:1 ratio). Usually in the anterior maxilla.
- Generally small (less than 3 cm). Larger lesions can cause buccal-lingual expansion and are often asymptomatic.
- Radiographic appearance: solitary, well-defined, often corticated unilocular or multilocular lesion (75% pericoronal). Pericoronal lesions typically extend apically beyond the cementoenamel junction, differentiating it from dentigerous cysts.
- Treatment typically involves sufficient enucleation due to the tumor's thick capsule.
- Prognosis is excellent with a rare recurrence rate.
Primary Intraosseous Carcinoma of the Jaws
- Carcinoma in the jaw with no connection to oral or skin epithelium.
- Often termed odontogenic carcinoma.
- May arise de novo, or in a pre-existing cyst, tumor.
- Residual radicular cysts and dentigerous cysts are potential sources.
- Mucoepidermoid carcinomas may originate from mucus cells in dentigerous cysts.
- Mostly affecting older adults in their 60s. Predominantly found in males.
- Common symptoms include pain and swelling.
- Radiographically: Radiolucency with irregular, ragged periphery.
- Histologically: Squamous cell carcinoma originating from the bone's epithelial lining, and mucoepidermoid carcinomas can be seen, originating from dentigerous cysts.
- Treatment involves resection, with or without chemotherapy and/or radiation.
Cementoblastoma
- Benign odontogenic tumor arising from cementoblasts.
- Commonly detected in late teens to early 20s.
- Most prevalent in the mandible, specifically the area of the first molar, with 75% occurring in the mandible, and 90% associated with the molar/premolar region.
- Typically painless but may exhibit symptoms of pain and swelling.
- Radiographically: Solitary lesion attached to tooth root. Commonly the first molar. Calcified mass attached to the tooth root, obscuring the root's outline. Radiopacity is often lobulated or radiating. Peripheral radiolucency is frequently present.
- Treatment involves removal of both the tooth and the attached tumor.
- Has excellent prognosis if completely removed.
- Histological features show sheets and trabeculae of cementum fused to the root with irregular lacunae. Multinucleated cells/blast cells line the trabeculae. Cellular fibrovascular connective tissue typically exists in-between the trabeculae.
Odontogenic Myxoma
- Benign ectomesenchymal odontogenic tumor.
- Resembles developing tooth microscopically.
- Most common in young adults (mean age 25-30), with a wide age range.
- Found slightly more often in mandible.
- Equally common in anterior and posterior locations.
- Generally asymptomatic, though larger lesions can cause slow, painless expansion, with potential for quick growth due to accumulated ground substance.
- Can cause pain, tooth and root resorption.
- Radiographically: Solitary lesion in the alveolar process, typically unilocular or multilocular, with an often irregular radiolucency. May exhibit delicate trabeculae, a "honeycomb" pattern. Can be large.
- Histologically: Characterized by delicate myxomatous connective tissue containing a ground substance matrix, mainly hyaluronic acid and chondroitin sulfate. Also has a few spindle shaped fibroblasts without a capsule. Resembles a dental papilla.
- Treatment involves curettage for small lesions or excision for larger ones.
Ameloblastic Fibroma
- Benign tumor of epithelial and ectomesenchymal odontogenic tissue.
- Most prevalent in the first and second decades of life.
- Equal frequency in males and females.
- Predominantly found in the posterior mandible (molar-ramus region) or maxilla.
- Asymptomatic. However, larger lesions can result in jaw expansion
- Radiographically: Solitary pericoronal (75%) lesion. Often well-defined, corticated radiolucency of variable size. Unilocular or multilocular.
- Potential for extending lesions into the jaw's ramus and body. Displacement of teeth and root resorption may occur in lesions.
- Histologically: Cords and islands of cuboidal odontogenic epithelium resembling ameloblastoma. Fibrous stroma with delicate tissue and mesenchymal cells similar to dental papilla.
- Treatment can be conservative excision, which is usually sufficient, with wider excision in recurrence cases.
- Rare transformation to ameloblastic fibrosarcoma.
Odontoma
- Benign odontogenic lesion of ectodermal and ectomesenchymal origin.
- Often considered a hamartoma rather than a neoplasm.
- Characterized by producing dental tissues (enamel, dentin, pulp) - commonly referred to as a "tooth tumor".
- Most common odontogenic lesion. Two types: compound and complex.
- Compound Odontomas are usually found in the anterior maxilla. These produce little teeth arranged in a well-organized manner, containing enamel, dentin, and pulp.
- Complex Odontomas typically occur in the posterior mandible or maxilla. They form an amorphous, jumbled mass of dental hard and soft tissues without distinct tooth forms.
- Radiographically: Compound Odontomas show multiple small tooth-forms, and complex Odontomas show an amorphous, radiopaque mass of dental tissues.
- Treatment involves excision; peripheral fibrous connective tissue capsule usually allows for complete removal.
- Recurrence rate is very rare.
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Description
Test your knowledge on odontogenic tumors, including their characteristics, demographics, and radiographic features. This quiz covers various aspects of tumors such as CEOT and ameloblastoma, as well as differential diagnoses. Perfect for dental students and professionals looking to reinforce their understanding of these conditions.