Podcast
Questions and Answers
Which type of cells are used in cell therapy to treat diseases or conditions?
Which type of cells are used in cell therapy to treat diseases or conditions?
- Differentiated cells (correct)
- Autologous cells
- Pluripotent stem cells
- HLA markers
What is the main advantage of using autologous cells in cell therapy?
What is the main advantage of using autologous cells in cell therapy?
- Longer life span
- Low immunogenicity (correct)
- Abundant source
- Faster FDA approval
What is the minimum number of HLAs that should match for a successful bone marrow transplant?
What is the minimum number of HLAs that should match for a successful bone marrow transplant?
- 2
- 4
- 8
- 6 (correct)
What is the main disadvantage of using autologous cells in cell therapy?
What is the main disadvantage of using autologous cells in cell therapy?
Which type of cells are collected from young, healthy donors and used to treat patients in cell therapy?
Which type of cells are collected from young, healthy donors and used to treat patients in cell therapy?
What is the risk associated with allogeneic cell therapy that can potentially shut down organs and be fatal?
What is the risk associated with allogeneic cell therapy that can potentially shut down organs and be fatal?
What is the advantage of allogeneic cells in cell therapy?
What is the advantage of allogeneic cells in cell therapy?
What are the two main types of lymphocytes involved in the immune response?
What are the two main types of lymphocytes involved in the immune response?
Which of the following is a key feature of CAR-T cell therapy products?
Which of the following is a key feature of CAR-T cell therapy products?
What is the main reason for sustained protein expression in CAR-T cell therapy?
What is the main reason for sustained protein expression in CAR-T cell therapy?
Which antigen do CAR-T cell therapies like Kymriah, Yescarta, Tecartus, and Breyanzi target?
Which antigen do CAR-T cell therapies like Kymriah, Yescarta, Tecartus, and Breyanzi target?
What are the common side effects of CAR-T cell therapy?
What are the common side effects of CAR-T cell therapy?
Which type of tumor is characterized by growths in organs or tissues that form lumps and can spread to other body parts if they metastasize?
Which type of tumor is characterized by growths in organs or tissues that form lumps and can spread to other body parts if they metastasize?
What is the function of Helper T-cells in the immune response?
What is the function of Helper T-cells in the immune response?
What is the role of cytotoxic granules released by immune cells in the immune response against cancer cells?
What is the role of cytotoxic granules released by immune cells in the immune response against cancer cells?
What type of tumor antigen is located on both normal cells and cancer cells but is abnormally expressed on cancer cells?
What type of tumor antigen is located on both normal cells and cancer cells but is abnormally expressed on cancer cells?
Which of the following is true about CAR-T cell therapy?
Which of the following is true about CAR-T cell therapy?
What is the function of the Transmembrane Domain in the Chimeric Antigen Receptor (CAR)?
What is the function of the Transmembrane Domain in the Chimeric Antigen Receptor (CAR)?
What is the purpose of the Linker in the Chimeric Antigen Receptor (CAR)?
What is the purpose of the Linker in the Chimeric Antigen Receptor (CAR)?
What is the role of CAR-T cell therapy in cancer treatment?
What is the role of CAR-T cell therapy in cancer treatment?
Which of the following is NOT true about blood transfusions?
Which of the following is NOT true about blood transfusions?
Who is credited with discovering blood types?
Who is credited with discovering blood types?
What is the main component in red blood cells that carries oxygen?
What is the main component in red blood cells that carries oxygen?
What is the purpose of bone marrow transplants?
What is the purpose of bone marrow transplants?
Which of the following is a challenge that impacts the efficacy of CAR-T cell therapy?
Which of the following is a challenge that impacts the efficacy of CAR-T cell therapy?
What happens when CAR-T cells face constant stimulation or overstimulation and release excessive cytokines?
What happens when CAR-T cells face constant stimulation or overstimulation and release excessive cytokines?
What is the term used to describe the turning off of CAR-T cells by a negative feedback mechanism?
What is the term used to describe the turning off of CAR-T cells by a negative feedback mechanism?
What impact does dysfunctional T-cells harvested from the patient have on CAR-T cell therapy?
What impact does dysfunctional T-cells harvested from the patient have on CAR-T cell therapy?
What is the role of inhibitory receptors on CAR-T cells in CAR-T cell exhaustion?
What is the role of inhibitory receptors on CAR-T cells in CAR-T cell exhaustion?
Which of the following is NOT a challenge that impacts the efficacy of CAR-T cell therapy?
Which of the following is NOT a challenge that impacts the efficacy of CAR-T cell therapy?
