Nylon Suture Degradation Study

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Questions and Answers

Which type of coating serves to increase pliability, reduce tissue drag, and improve tying characteristics?

  • Water-soluble coating
  • Proprietary silicon coating
  • Water-insoluble coating (correct)
  • Antibiotic coating

What is the purpose of the water-soluble coating on polyglycolic acid suture (Dexon II)?

  • Enhance tissue drag
  • Reduce knot security
  • Improve pliability
  • Facilitate knot formation (correct)

How do water-insoluble coatings affect knot security compared to uncoated suture?

  • Increase knot security
  • Have no effect on knot security
  • Make tissue drag worse
  • Reduce knot security (correct)

What is the effect of an alkaline environment on sutures with a glycolide component?

<p>They degrade rapidly (C)</p> Signup and view all the answers

What happens to sutures with a dioxanone component in an acid environment?

<p>They lose tensile strength rapidly (A)</p> Signup and view all the answers

How does polypropylene, a nonabsorbable suture, react in acidic conditions?

<p>It remains unaffected (C)</p> Signup and view all the answers

How does nylon suture, generally non-absorbable, react in acidic conditions?

<p>It loses tensile strength (D)</p> Signup and view all the answers

In what conditions does polyglactin 910 (Vicryl) have the least reduction in tensile strength?

<p>Neutral solution (A)</p> Signup and view all the answers

How does polyglactin 910 (Vicryl) behave in alkaline solutions?

<p>It loses tensile strength rapidly (B)</p> Signup and view all the answers

What impact do bodily fluids like pancreatic secretions have on suture degradation?

<p>Variety of impacts (A)</p> Signup and view all the answers

How does exposure to infected milk impact suture strength?

<p>Reduces strength (D)</p> Signup and view all the answers

True or False: Catgut suture is uniform in diameter throughout its length.

Signup and view all the answers

True or False: Catgut undergoes additional curing processes with chromium trioxide salts which decreases collagen cross-linkages.

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How does the presence of synovial fluid impact the rate of suture absorption?

<p>Increases absorption rate (A)</p> Signup and view all the answers

How does the rate of application and amount of strain affect the ability of suture to withstand tensile load over time?

<p>Increases ability to withstand load (C)</p> Signup and view all the answers

Which suture material is suitable for ligation of small vessels or suturing rapidly healing tissues?

<p>Catgut (C)</p> Signup and view all the answers

What is the approximate time it takes for Polyglycolic acid to be completely absorbed?

<p>60 to 90 days (A)</p> Signup and view all the answers

Which suture type had the highest breaking stress when compared against other materials?

<p>Polyglycolic acid (C)</p> Signup and view all the answers

Which suture material is coated with calcium stearate and polyglactic acid to improve handling characteristics?

<p>Polyglactin 910 (D)</p> Signup and view all the answers

In what period does Poliglecaprone 25 lose approximately 50% of its strength after implantation in rat subcutis?

<p>1 week (D)</p> Signup and view all the answers

Which suture material has lesser knot security when compared to chromic gut?

<p>Polyglytone 6211 (D)</p> Signup and view all the answers

What is a significant benefit of using triclosan impregnated sutures in human surgery according to the text?

<p>Decrease in rate of incisional infection (C)</p> Signup and view all the answers

How are natural absorbable sutures like catgut primarily absorbed in living tissue?

<p>Enzymatic actions of cellular proteases and collagenases (B)</p> Signup and view all the answers

Which compound mentioned in the text is NOT used to coat sutures for improving wound healing?

<p>Acetic acid (A)</p> Signup and view all the answers

What is a significant factor affecting the rate of suture absorption mentioned in the text?

<p>The biochemical environment (D)</p> Signup and view all the answers

In the study mentioned, how did polydioxanone (PDS) suture behave when exposed to sterile urine?

<p>Lost all strength in 3 days (A)</p> Signup and view all the answers

What role do acid phosphatase and leucine aminopeptidase play in the enzymatic absorption of catgut suture according to the text?

<p>They play major enzymatic roles (C)</p> Signup and view all the answers

What happens to polyglycolic acid (Dexon) suture when exposed to Proteus-infected urine?

<p>Lost all strength after 1 day (A)</p> Signup and view all the answers

'Absorbable suture' is commonly defined as suture that loses most of its tensile strength within how many days in living mammalian tissue?

<p>~60 to 90 days (D)</p> Signup and view all the answers

'Absorbable suture' as defined by USP is absorbed by what type of tissue according to the text?

<p>'Living, mammalian tissue' (A)</p> Signup and view all the answers

In what way are synthetic absorbable sutures primarily absorbed according to the text?

<p>Hydrolysis by random main-chain scission of ester linkages (D)</p> Signup and view all the answers

What factors can result in considerable variation in the rate of suture absorption according to the text?

<p>Material, coatings, size, and biochemical environment (D)</p> Signup and view all the answers

How did catgut suture behave when exposed to infected urine compared to sterile urine?

<p>Showed increased absorption rates in infected urine (D)</p> Signup and view all the answers

What is a potential issue with using nylon sutures for implantation?

<p>Susceptibility to degradation (B)</p> Signup and view all the answers

Why is caution advised when using nylon leader line in veterinary orthopedic repair?

<p>It is prone to elongation (D)</p> Signup and view all the answers

Which sterilization technique results in an increase in elongation of monofilament nylon leader line?

<p>Steam sterilization (C)</p> Signup and view all the answers

Why is polymerized caprolactam suture not recommended for implantation in tissues?

<p>Can cause sinus formation (C)</p> Signup and view all the answers

Which characteristic makes Ethibond Excel a preferred suture for musculoskeletal surgery?

<p>Polybutylate coating for handling qualities (C)</p> Signup and view all the answers

What is the composition of Ti-Cron sutures?

<p>Long-chain, high-molecular-weight, linear polyester fibers (B)</p> Signup and view all the answers

How do steam sterilization and ethylene oxide sterilization affect the mechanical properties of fishing line differently?

<p>Steam sterilization increases elongation, while ethylene oxide sterilization does not affect ultimate strength. (C)</p> Signup and view all the answers

What distinguishes leader line from regular fishing line?

<p>Material composition (A)</p> Signup and view all the answers

What makes Surgidac a versatile suture choice?

<p>Available as monofilament or multifilament with different coatings (A)</p> Signup and view all the answers

Why is caution advised when using nylon leader line as an implantable biomaterial?

<p>It loses tensile strength after implantation due to hydration and degradation (B)</p> Signup and view all the answers

How does nylon leader line differ from regular fishing line in its intended use?

<p>Nylon leader line is primarily used in saltwater fishing for larger fish with strong jaws and sharp teeth (D)</p> Signup and view all the answers

Which suture material has better handling and less memory compared to polyglyconate?

<p>Polydioxanone (D)</p> Signup and view all the answers

What is the approximate strength retention of polyglyconate after 4 to 5 weeks?

<p>50% (D)</p> Signup and view all the answers

Which suture material is slowly degraded by hydration even though it's considered nonabsorbable?

<p>Silk (C)</p> Signup and view all the answers

Among silk, nylon, polyester, and gut, which suture material has the highest energy to break point?

<p>Nylon (A)</p> Signup and view all the answers

Which suture material has the highest knot strength among polyglyconate, polydioxanone, and polypropylene?

<p>Polyglyconate (D)</p> Signup and view all the answers

What is the monofilament absorbable suture composed of glycolide, dioxanone, and trimethylene carbonate?

<p>Glycomer 631 (D)</p> Signup and view all the answers

'Silk should be avoided in any application where excessive inflammation is undesirable' - Which characteristic of silk supports this statement?

<p>'Silk having a relatively high tissue reactivity' (A)</p> Signup and view all the answers

'Silk is used frequently for ligation of large vessels' - Why does silk have this specific application according to the text?

<p>'Silk being a natural, braided suture' (D)</p> Signup and view all the answers

Which nonabsorbable suture material is most slowly degraded by hydration?

<p>Silk (A)</p> Signup and view all the answers

What makes silk a preferred choice for ligation of large vessels?

<p>Good knot security (B)</p> Signup and view all the answers

Which suture material has poor knot tying characteristics when used within arthroscopic cannulas?

<p>Surgidac (A)</p> Signup and view all the answers

What is the distinguishing characteristic of polybutester suture among most sutures?

<p>Marked elasticity (D)</p> Signup and view all the answers

Which suture material elongates approximately 4 times more than nylon at 2 N of force?

<p>Polybutester (D)</p> Signup and view all the answers

What are Polydek and Tevdek examples of?

<p>Coated and braided polyethylene sutures (C)</p> Signup and view all the answers

Which composite suture has a multifilament ultra-high-molecular-weight polyethylene core?

<p>FiberWire (A)</p> Signup and view all the answers

What is the distinguishing feature of FiberWire compared to braided polyester sutures?

<p>Greater knot security and abrasion resistance (C)</p> Signup and view all the answers

What is the primary application of stainless steel sutures?

<p>Musculoskeletal applications (C)</p> Signup and view all the answers

Which suture material has characteristics theorized to be advantageous when closing postoperatively swelling wounds?

<p>Polybutester (D)</p> Signup and view all the answers

What is the key difference between Polydek and Tevdek sutures regarding their coating with polytetrafluoroethylene?

<p>Polydek is impregnated, Tevdek is lightly coated (C)</p> Signup and view all the answers

Which composite suture maintains stiffness until ultimate failure, unlike Stainless Steel?

<p>FiberWire (A)</p> Signup and view all the answers

What is the primary reason for the replacement of Stainless Steel suture by polyblend composite sutures?

<p>Strength (B)</p> Signup and view all the answers

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