Nursing Application: Antilipemics Flashcards
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Questions and Answers

Which priority assessments should be completed before administering antilipemic medications to a patient? (Select all that apply)

  • Baseline vital signs (correct)
  • Known allergies (correct)
  • Last bowel movement (correct)
  • Drug-drug interactions (correct)
  • What should the nurse advise a client experiencing flushing after taking niacin?

    If you have some available, take an aspirin now.

    Place each antilipemic drug into the correct class:

    lovastatin = HMG-CoA Reductase Inhibitors simvastatin = HMG-CoA Reductase Inhibitors colesevelam = Bile Acid Sequestrants cholestyramine = Bile Acid Sequestrants gemfibrozil = Fibric Acid Derivatives fenofibrate = Fibric Acid Derivatives

    What data should the nurse collect prior to administering the first dose of a prescribed antilipemic medication? (Select all that apply)

    <p>Serum lipid levels</p> Signup and view all the answers

    What adverse effect should the nurse be aware of when a patient reports a sore abdomen and yellowish eyes?

    <p>Hepatic dysfunction</p> Signup and view all the answers

    What teaching should be included for a patient taking fenofibric acid and warfarin?

    <p>You will need to have your bleeding labs checked more frequently for a while.</p> Signup and view all the answers

    Which foods should a client taking cholestyramine restrict? (Select all that apply)

    <p>Cholesterol</p> Signup and view all the answers

    What laboratory result indicates effective treatment for a patient taking gemfibrozil?

    <p>The patient's cholesterol decreased.</p> Signup and view all the answers

    Which medication raises concern when prescribed with atorvastatin?

    <p>Erythromycin</p> Signup and view all the answers

    What statements should be included in patient education about cholestyramine? (Select all that apply)

    <p>Notify the physician if your stool becomes frothy or foul smelling.</p> Signup and view all the answers

    What medication does the nurse anticipate prescribing for a woman with hyperlipidemia planning to start a family?

    <p>New prescription for a bile acid sequestrant.</p> Signup and view all the answers

    What condition does ezetimibe help reduce risk for?

    <p>Atherosclerosis</p> Signup and view all the answers

    What indicates a patient understands their simvastatin dosing schedule?

    <p>I take this at night since my liver processes lipids in the early morning hours.</p> Signup and view all the answers

    What laboratory studies are likely to be ordered for a client on simvastatin for six months? (Select all that apply)

    <p>Liver function studies</p> Signup and view all the answers

    Match the following effects with their respective antilipemic categories:

    <p>Bind to bile, leading to decreased serum LDL = Bile Acid Sequestrants Activate lipoprotein lipase = Fibric Acid Derivatives Inhibit enzyme needed to synthesize cholesterol = HMG-CoA Reductase Inhibitors</p> Signup and view all the answers

    Study Notes

    Priority Assessments Before Antilipemic Medications

    • Assess known allergies to prevent adverse reactions.
    • Evaluate the last bowel movement to monitor gastrointestinal function.
    • Review potential drug-drug interactions for safety.
    • Establish baseline vital signs for ongoing monitoring.

    Reaction to Niacin (Nicotinic Acid)

    • Flushing and warmth after niacin indicates a common side effect, not an allergic reaction.
    • A recommended action is to take an aspirin to mitigate flushing effects.

    Classes of Antilipemic Drugs

    • HMG-CoA Reductase Inhibitors: Lovastatin, Simvastatin
    • Bile Acid Sequestrants: Colesevelam, Cholestyramine
    • Fibric Acid Derivatives: Gemfibrozil, Fenofibrate

    Data Collection Prior to Antilipemic Administration

    • Serum lipid levels should be checked to assess cholesterol before treatment.
    • Record the last bowel movement for gastrointestinal health.
    • Note the time of the last meal to ensure proper dosing timing.

    Adverse Effects of Antilipemics

    • Symptoms like abdominal pain and jaundice could indicate hepatic dysfunction.

    Teaching for Fenofibric Acid

    • Inform patients on warfarin to have bleeding labs monitored more frequently due to interaction risks.

    Food Restrictions with Cholestyramine

    • Advise avoidance of high carbohydrates, cholesterol, and fat to enhance medication efficacy.

    Effectiveness of Gemfibrozil

    • Decrease in cholesterol levels indicates successful treatment.

    Drug Interaction Concerns

    • Caution when prescribing atorvastatin alongside erythromycin due to potential interactions.

    Patient Education for Cholestyramine

    • Medication should be taken before meals.
    • Can be mixed with noncarbonated beverages.
    • Report frothy or foul-smelling stools to a physician.
    • Importance of adhering to a low-fat, low-cholesterol diet.

    Pregnancy Considerations with Simvastatin

    • Anticipate the use of bile acid sequestrants for women planning to conceive.

    Ezetimibe and Atherosclerosis Risk

    • Ezetimibe is aimed at reducing risks associated with atherosclerosis.

    Dosing Schedule for Simvastatin

    • Simvastatin is ideally taken at night to align with liver lipid processing.

    Teaching for Omega-3 Acid Ethyl Esters

    • Maintain a low-fat diet despite medication use.
    • Can be taken with meals to reduce gastrointestinal discomfort.
    • Stress control of diabetes for triglyceride management.
    • Encourage a balanced exercise routine alongside medication.

    Laboratory Studies for Simvastatin Monitoring

    • Monitor total cholesterol and triglycerides for treatment effectiveness.
    • Assess HDL and LDL levels to evaluate cardiovascular risk.
    • Conduct liver function tests to prevent hepatic issues.

    Mechanisms of Action for Antilipemics

    • Bile Acid Sequestrants: Bind bile to reduce LDL cholesterol by promoting hepatic absorption of serum cholesterol.
    • Fibric Acid Derivatives: Activate lipoprotein lipase to breakdown cholesterol.
    • HMG-CoA Reductase Inhibitors: Inhibit cholesterol synthesis effectively lowering serum cholesterol levels.

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    Test your knowledge on antilipemic medications with these informative flashcards. Assess key concepts such as priority assessments, patient education, and medication interactions relevant to nursing practice. Enhance your understanding to provide better patient care.

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