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Questions and Answers
What is the primary focus of epidemiology?
What is the primary focus of epidemiology?
Which of the following best describes descriptive epidemiology?
Which of the following best describes descriptive epidemiology?
In analytical epidemiology, which method focuses on comparing groups with and without the disease?
In analytical epidemiology, which method focuses on comparing groups with and without the disease?
What are notifiable diseases?
What are notifiable diseases?
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Which term best describes the incidence of specific notifiable diseases?
Which term best describes the incidence of specific notifiable diseases?
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What is the role of experimental epidemiology?
What is the role of experimental epidemiology?
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Which of the following is NOT a characteristic of analytical epidemiology?
Which of the following is NOT a characteristic of analytical epidemiology?
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What is the significance of early epidemiologists like Snow and Nightingale?
What is the significance of early epidemiologists like Snow and Nightingale?
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Which type of disease is classified as easily spread between hosts?
Which type of disease is classified as easily spread between hosts?
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Which term describes infections that are always present in a specific environment?
Which term describes infections that are always present in a specific environment?
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What describes a disease that develops quickly and resolves rapidly?
What describes a disease that develops quickly and resolves rapidly?
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Which type of infection is limited to a small area of the body?
Which type of infection is limited to a small area of the body?
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Which condition is identified as a secondary infection?
Which condition is identified as a secondary infection?
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What term refers to infections characterized by the host not showing symptoms?
What term refers to infections characterized by the host not showing symptoms?
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What is a key characteristic of a pandemic?
What is a key characteristic of a pandemic?
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Which of the following best defines the term 'incidence' in disease classification?
Which of the following best defines the term 'incidence' in disease classification?
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Which of the following infections is an example of a chronic disease?
Which of the following infections is an example of a chronic disease?
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Which of these examples best represents an opportunistic infection?
Which of these examples best represents an opportunistic infection?
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Study Notes
Course Information
- Course title: NURS 236: Human-microbe interactions and epidemiology
- Course part: Principles of epidemiology and disease
Learning Objectives
- Explain the principles of the epidemiology of infectious diseases in humans.
- List Koch's postulates.
- Compare communicable and non-communicable diseases.
- Distinguish terms for the occurrence and severity of disease.
- Recognize the different impacts on the host.
Epidemiology
- Study of disease progression within a population (includes when and where)
- Similar to medical detectives, looking for non-medical factors that contribute to health changes
- Considers etiology, risk factors (including infections, societal practices, control of reservoirs, vectors)
- Early epidemiologists include Snow and Nightingale
- Snow: Cholera contaminated well
- Nightingale: Typhus in armies (food, sanitation, disease)
Epidemiology: Types
- Descriptive: Collects all data about the disease being examined (mostly retrospective, after an event—e.g., cholera after the Haitian earthquake)
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Analytical: Analyzes a disease to determine etiology—e.g., Case control & Cohort studies
- Case control: Compares groups with and without the disease to identify causes or risk factors
- Cohort: Groups with or without exposure to the disease
- Experimental: Hypothesis testing; how disease spreads, factors influencing spread and treatment; compares control vs. experimental groups, controlling other variables.
Epidemiology: Terms
- Notifiable diseases: Infections reported to public health bodies (http://dsol-smed.phac-aspc.gc.ca/dsol-smed/ndis/list-eng.php—Canada)
- Morbidity: Incidence of specific notifiable diseases
- Mortality: Deaths caused by notifiable diseases
- (NOTE: additional terms will likely be covered later in the course, given the learning objectives)
Koch's Postulates
- Microorganisms are isolated from a diseased/dead animal
- Microorganisms are grown in a pure culture
- Microorganisms are injected into a healthy host
- Disease is reproduced in the host
- Microorganisms are re-isolated from the host
Classifying Human Disease
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Communicable: Spreads between hosts (humans or animals); contagious=easily communicable (e.g., chickenpox, measles, herpes, typhoid fever)
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Non-communicable: Does not spread between hosts; normal microbiota that occasionally causes disease (opportunistic) OR microbes that normally live in the environment causing disease in humans (e.g., Clostridium tetani, Cryptococcus gattii, Naegleria fowleri)
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Classifying Human Disease: Occurrences
- Incidence: New infections;
- Prevalence: New and existing infections (more relevant for long-term infections)
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Classifying Human Disease: Frequency
- Sporadic: Only shows up occasionally (e.g., typhoid fever in the US)
- Endemic: Always present in an area –E.g. common cold, malaria in certain areas
- Epidemic: Many new infections in an area over a short period—e.g. seasonal influenza, MRSA in a hospital setting
- Pandemic: Epidemic disease at a global scale (e.g., AIDS, 1918 influenza)
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Classifying Human Disease: Severity/Duration
- Acute: Develops quickly and resolves quickly—e.g., influenza
- Chronic/Persistent: Develops slowly and is longer lasting—e.g., infectious mononucleosis, TB, hepatitis B
- Latent: Inactive period before producing symptoms—e.g., Shingles
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Classifying Human Disease: Host Involvement/Impact
- Local infections: Limited to a small area of the body—e.g., boils, pimples
- Systemic/generalized infections: Throughout the body—e.g., measles; spread by blood or lymph
- Primary infection: Initial infection
- Secondary infection: Infection that results from weakening of the immune system by a primary infection
- Subclinical/inapparent infection: Asymptomatic; carrier of an organism
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Description
This quiz focuses on the principles of epidemiology as they relate to infectious diseases in humans. You will explore key concepts such as Koch's postulates and the distinctions between communicable and non-communicable diseases. Delve into the historical contributions of early epidemiologists like Snow and Nightingale in understanding disease dynamics.