Nucleotides Composition and Structure

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What are the two families of nitrogenous bases?

Pyrimidines and purines

Which type of sugar is found in DNA nucleotides?

Deoxyribose

What type of bonds join adjacent nucleotides in a polynucleotide?

Phosphodiester linkages

What is the name given to nitrogenous bases that can bond together due to their shapes?

Complementary bases

In a DNA molecule, how do the two polynucleotides run in relation to each other?

Antiparallel

Why is DNA used for long-term information storage in cells instead of RNA?

DNA is more stable and less prone to degradation

How many covalent bonds can carbon form?

4

Which atoms are involved in forming covalent bonds in organic molecules?

Carbon, hydrogen, nitrogen

What gives organic molecules different chemical properties?

Functional groups

How are macromolecules formed from monomers?

Condensation reactions

What is the general term for the building blocks of proteins?

Amino acids

What is the term for the long molecules formed by many amino acids linked together?

Polypeptides

What is a structural difference between DNA and RNA?

In DNA, the nitrogenous base thymine is replaced by uracil in RNA.

Which pentose sugar is found in DNA?

Deoxyribose

What are the major functions of carbohydrates?

Fuel, building material, and cell identity markers

What type of bond is formed between two monosaccharides during polymerization?

Glycosidic bond

Which nitrogenous base is unique to RNA and not found in DNA?

Uracil

What is the general term for the monomers of carbohydrates?

Monosaccharides

Which type of polysaccharide is primarily used by animals for energy storage?

Glycogen

What is the function of cellulose in plant cell walls?

Structural support

Which class of large biological molecules do not form polymers?

Lipids

What is the primary reason why lipids are hydrophobic?

Consist mostly of carbon-hydrogen bonds

Which lipid is important for cell membranes due to its amphipathic nature?

Phospholipids

What do lipids primarily function as in biological systems?

Energy storage

How is the primary structure of a protein determined?

By the unique sequence of amino acids in a protein

What can radically alter protein function?

A single amino acid change

What is responsible for forming a protein's secondary structure?

Hydrogen bonds between the carboxyl group and the amino group

What contributes to the distinctive three-dimensional shape of a polypeptide?

Interactions between R-groups and the peptide backbone

When does a protein acquire its unique three-dimensional shape?

At the primary structure level

What results in quaternary structure in proteins?

Two or more polypeptide chains coming together

Where does protein synthesis take place in a eukaryotic cell?

Cytosol

Which component of the endomembrane system is mainly involved in the synthesis of lipids?

Endoplasmic reticulum

What is the function of rough endoplasmic reticulum (ER) in protein synthesis?

It has ribosomes attached and is involved in protein synthesis

Which region of the endoplasmic reticulum lacks ribosomes?

Smooth ER

What is the main function of smooth endoplasmic reticulum (ER) in a eukaryotic cell?

Detoxification of chemicals

Which organelle is responsible for modifying, packaging, and transporting lipids and proteins in a eukaryotic cell?

Golgi apparatus

What is the primary function of microfilaments in cell division of animal cells?

Pulling the duplicated chromosomes to opposite ends of the dividing cell

What structures are found in the centrosome of animal cells?

Pairs of centrioles

What happens during cytokinesis in animal cells?

Cytoplasm is equally distributed into two daughter cells

What is the role of centrioles in cell division?

Pulling duplicated chromosomes to opposite ends of the dividing cell

Why is the exact function of centrioles in cell division unclear?

Even without centrosomes, cells can still divide

What is the main function of the Golgi apparatus?

Modification, sorting, and packaging of macromolecules

What would be the consequence if the lysosomal membrane breaks down?

Release of inactive hydrolytic enzymes at neutral pH

At what pH are the hydrolytic enzymes within lysosomes active?

pH 5

What is the primary function of lysosomes in a cell?

Digestion of macromolecules

Which organelle in a eukaryotic cell is primarily responsible for packaging materials into transport vesicles?

Golgi apparatus

What maintains the acidic internal pH of lysosomes?

Proton pump in the lysosomal membrane

Which molecules can cause oxidative stress in cells by reacting with and damaging DNA and lipid-based molecules?

ROSs

Which component of the cytoskeleton is responsible for anchoring the nucleus and certain organelles in a cell?

Intermediate filaments

What is the function of microfilaments within a cell?

Cytoplasmic streaming

Which components control the beating of cilia and flagella in cells?

Microtubules

What is the primary role of catalases and peroxidases within cells?

Breaking down ROSs

In what cellular activity are microtubules, microfilaments, and intermediate filaments all involved?

Cell motility

What distinguishes plant cells from animal cells in terms of their extracellular structure?

Plant cells have a cell wall while animal cells have an extracellular matrix (ECM)

Which protein is the most abundant in the extracellular matrix (ECM) of most animal cells?

Collagen

What are some key functions of the extracellular matrix (ECM) of animal cells?

Structural support, cell movement, and cell-to-cell signaling

Which molecule is responsible for protecting the plant cell, maintaining its shape, and preventing excessive water uptake?

Cellulose fibers

What do ECM proteins bind to in the plasma membrane of animal cells?

Integrins

What type of carbohydrates are plant cell walls primarily made of?

Polysaccharides

Learn about the components of nucleotides, including nitrogenous bases, pentose sugar, and phosphate group. Explore the two families of nitrogenous bases - pyrimidines (cytosine, thymine, and uracil) and purines (adenine and guanine). Understand the differences between DNA and RNA in terms of sugar composition.

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